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A dual graph neural network for drug-drug interactions prediction based on molecular structure and interactions.
Published 2023-01-01“…Second, in order to improve the final features, we separated the drug-drug interactions into pairwise interactions between each drug's unique substructures. …”
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382
Editorial: The pharmacotherapy of depression-searching for new mechanisms and drug interactions. Basic and clinical research, volume II
Published 2024-03-01Subjects: Get full text
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383
Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses
Published 2024-03-01“…Here, we tested the hypothesis that drug-drug interactions vary in different media, and determined which in vitro models best predict drug interactions in the lungs. …”
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384
A dual graph neural network for drug–drug interactions prediction based on molecular structure and interactions
Published 2023-01-01“…Author summary Drug-drug interactions (DDIs) may cause adverse effects that damage the body. …”
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385
Prevalence of Drug–Drug Interactions in Primary Care Prescriptions in Egypt: A Cross-Sectional Retrospective Study
Published 2023-06-01Subjects: “…drug interactions…”
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386
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Contemplating cannabis? The complex relationship between cannabinoids and hepatic metabolism resulting in the potential for drug-drug interactions
Published 2023-01-01Subjects: Get full text
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389
Potential drug–drug interactions in patients with cardiovascular diseases: findings from a prospective observational study
Published 2021-12-01Subjects: Get full text
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390
Prediction of Drug-Drug Interaction Using an Attention-Based Graph Neural Network on Drug Molecular Graphs
Published 2022-05-01Subjects: “…drug-drug interaction…”
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391
Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants
Published 2024-02-01“…Cumulative safety and no clinically meaningful PK drug interactions observed in this study supported co‐administration of these two novel agents in additional studies exploring efficacy and safety in the management of NAFLD.…”
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392
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Potential Cytochrome P450 Drug-Drug Interaction Among Adult and Adolescent Patients Undergoing Tonsillectomy
Published 2020-06-01“…Objective To assess the frequency of potential drug-drug interactions affecting cytochrome P450 (CYP)–mediated metabolism of opioids among adult and adolescent patients who underwent adenotonsillectomy. …”
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394
Importance of Therapeutic Drug Monitoring to Detect Drug Interaction between Pazopanib and Warfarin: A Case Report
Published 2020-05-01“…In this case, blood levels of pazopanib were abnormally high, possibly causing liver dysfunction and drug interactions, leading to his PT-INR prolongation. …”
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395
Evaluation of the drug–drug interaction potential of brigatinib using a physiologically‐based pharmacokinetic modeling approach
Published 2024-04-01“…In vitro studies indicated that brigatinib is primarily metabolized by CYP2C8 and CYP3A4 and inhibits P‐gp, BCRP, OCT1, MATE1, and MATE2K. Clinical drug–drug interaction (DDI) studies with the strong CYP3A inhibitor itraconazole or the strong CYP3A inducer rifampin demonstrated that CYP3A‐mediated metabolism was the primary contributor to overall brigatinib clearance in humans. …”
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396
Adverse drug reactions and drug interactions in the treatment of hospitalized patients with coronavirus disease 2019 (COVID-19)
Published 2021-01-01Subjects: Get full text
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397
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Prevalence of drug-drug interactions in oncology patients enrolled on National Clinical Trials Network oncology clinical trials
Published 2018-11-01Subjects: “…Oncology clinical trial drug interaction…”
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400
Major Interaction between Warfarin and Na Valproate: A Case Report
Published 2015-10-01Subjects: Get full text
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