Assessment of risk factors associated with potential drug-drug interactions among patients suffering from chronic disorders. by Muhammad Fawad Rasool, Anees Ur Rehman, Irfanullah Khan, Muhammad Latif, Imran Ahmad, Sadia Shakeel, Muhammad Sadiq, Khezar Hayat, Shahid Shah, Waseem Ashraf, Abdul Majeed, Iltaf Hussain, Rabia Hussain

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Caenorhabditis elegans as a valuable model for the study of anthelmintic pharmacodynamics and drug-drug interactions: The case of ivermectin and eprinomectin by Gonzalo Suárez, Ignacio Alcántara, Gustavo Salinas, Gustavo Salinas

“…The results highlight the utility of C. elegans to address pharmacodynamics studies, particularly for drug-drug interactions. Models in vitro can be integrated to facilitate preclinical and clinical translational studies and help researchers to understand drug-drug interactions and achieve rational therapeutic regimes.…”
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Potential drug–drug interactions in inpatients treated at the Internal Medicine ward of Tikur Anbessa Specialized Hospital by Tesfaye ZT, Nedi T

Subjects: “…drug-drug interactions…”
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Rationale, design, and methodology of the EPIC (Epidemiology of Polypharmacy and Potential Drug-Drug Interactions in Elderly Cardiac Outpatients) study by Eda Özlek, Edip Güvenç Çekiç, Bülent Özlek, Cem Çil, Oğuzhan Çelik, Volkan Doğan, Özcan Başaran, Veysel Ozan Tanık, Halil İbrahim Özdemir, Yunus Çelik, Caner Kaçmaz, Zeki Şimşek, Hacı Murat Güneş, Özgen Şafak, Buğra Özkan, Onur Tasar, Çağatay Önal, Lütfü Bekar, Murat Biteker

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Leveraging National Claims and Hospital Big Data: Cohort Study on a Statin-Drug Interaction Use Case by Aurélie Bannay, Mathilde Bories, Pascal Le Corre, Christine Riou, Pierre Lemordant, Pascal Van Hille, Emmanuel Chazard, Xavier Dode, Marc Cuggia, Guillaume Bouzillé

“…Only 121 patients had the most severe level of statin-drug interaction. Hospital stay burden (length of stay and in-hospital mortality) was more severe in patients with statin-drug interactions during hospitalization. …”
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Cognitive task analysis of clinicians’ drug–drug interaction management during patient care and implications for alert design by Nervana Elkhadragy, Amanda P Ifeachor, Julie B Diiulio, Karen J Arthur, Michael Weiner, Laura G Militello, Peter A Glassman, Alan J Zillich, Alissa L Russ-Jara

“…Background Drug–drug interactions (DDIs) are common and can result in patient harm. …”
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Assessment of risk factors associated with potential drug-drug interactions among patients suffering from chronic disorders by Muhammad Fawad Rasool, Anees ur Rehman, Irfanullah Khan, Muhammad Latif, Imran Ahmad, Sadia Shakeel, Muhammad Sadiq, Khezar Hayat, Shahid Shah, Waseem Ashraf, Abdul Majeed, Iltaf Hussain, Rabia Hussain

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Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects by JungJin Oh, Eunsol Yang, In-Jin Jang, Hyejung Lee, Hokyun Yoo, Jae-Yong Chung, SeungHwan Lee, Jaeseong Oh

Subjects: “…drug interactions…”
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Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice by Malavika Deodhar, Sweilem B Al Rihani, Meghan J. Arwood, Lucy Darakjian, Pamela Dow, Jacques Turgeon, Veronique Michaud

Subjects: “…drug–drug interactions…”
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Potentially clinically significant drug-drug interactions in older patients admitted to the hospital: A cross-sectional study by Zuzana Očovská, Martina Maříková, Martina Maříková, Jiří Vlček, Jiří Vlček

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Assessment of drug–drug interaction potential with EDP‐305, a farnesoid X receptor agonist, in healthy subjects by Alaa Ahmad, Nathalie Adda

“…Four studies were conducted in healthy volunteers to evaluate the drug–drug interaction (DDI) potential of EDP‐305 co‐administered with drugs known to be substrates for drug metabolizing enzymes or transporters, and to assess the effect of inhibitors and inducers of CYP3A4 on EDP‐305. …”
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Drug Interaction between Dexamethasone and Ketoprofen with Thiopental in Male Dogs: Effect on the Recovery from Anesthesia and Pharmacokinetics Parameters by Mahdieh Raeeszadeh, Mohammad Pouya Ghaffari

“…Drug-drug interactions (DDIs) are an important part of clinical veterinary pharmacology. …”
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Evaluation and Management of Drug-Drug Interactions in Patients Hospitalized in Nephrology and Post-Transplant Wards in a Teaching Hospital by Mojtaba Shafiekhani, Sara Tarighati, Ehsan Mirzaei, Soha Namazi

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Factors associated with a basic common drug-drug interaction knowledge among emergency department medical personnel by Theerapon Tangsuwanaruk, Borwon Wittayachamnankul

Subjects: “…Drug interactions…”
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Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat by Sebastian Frechen, Ibrahim Ince, André Dallmann, Michael Gerisch, Natalia A. Jungmann, Corina Becker, Maximilian Lobmeyer, Maria E. Trujillo, Shiyao Xu, Rolf Burghaus, Michaela Meyer

“…Preclinical studies have demonstrated that the primary route of metabolism for vericiguat is glucuronidation, mainly catalyzed by uridine diphosphate‐glucuronosyltransferase (UGT)1A9 and to a lesser extent UGT1A1. Whereas a drug–drug interaction (DDI) study of the UGT1A9 inhibitor mefenamic acid showed a 20% exposure increase, the effect of UGT1A1 inhibitors has not been assessed clinically. …”
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Modulatory Effects of Atractylodin and β-Eudesmol on Human Cytochrome P450 Enzymes: Potential Drug-Drug Interactions by Artitaya Thiengsusuk, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang

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Evaluation of potential drug-drug interactions in hospitalized patients at a tertiary care hospital: A pilot study by Yesim Kaya Yasar, Seckin Engin, Elif Nur Barut, Serhat Sevgi, Gamze Eroglu, Feride Sena Sezen

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Islatravir Is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions via Major Drug-Metabolizing Enzymes or Transporters by Kelly Bleasby, Robert Houle, Michael Hafey, Meihong Lin, Jingjing Guo, Bing Lu, Rosa I. Sanchez, Kerry L. Fillgrove

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Adverse drug reactions and correlations with drug–drug interactions: A retrospective study of reports from 2011 to 2020 by Huaqiao Jiang, Yanhua Lin, Weifang Ren, Zhonghong Fang, Yujuan Liu, Xiaofang Tan, Xiaoqun Lv, Ning Zhang

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Reporting a lethal drug interaction occurred during evaluation of insulin resistance in mice polycystic ovary model by Seyyed Amir Yasin Ahmadi, Afshin Hasanvand, Amin Hasanvand, Mandana Beigi Boroujeni, Fatemeh Yari

Subjects: “…Drug interaction…”
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