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Caenorhabditis elegans as a valuable model for the study of anthelmintic pharmacodynamics and drug-drug interactions: The case of ivermectin and eprinomectin
Published 2022-10-01“…The results highlight the utility of C. elegans to address pharmacodynamics studies, particularly for drug-drug interactions. Models in vitro can be integrated to facilitate preclinical and clinical translational studies and help researchers to understand drug-drug interactions and achieve rational therapeutic regimes.…”
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423
Potential drug–drug interactions in inpatients treated at the Internal Medicine ward of Tikur Anbessa Specialized Hospital
Published 2017-08-01Subjects: “…drug-drug interactions…”
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424
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425
Leveraging National Claims and Hospital Big Data: Cohort Study on a Statin-Drug Interaction Use Case
Published 2021-12-01“…Only 121 patients had the most severe level of statin-drug interaction. Hospital stay burden (length of stay and in-hospital mortality) was more severe in patients with statin-drug interactions during hospitalization. …”
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426
Cognitive task analysis of clinicians’ drug–drug interaction management during patient care and implications for alert design
Published 2023-12-01“…Background Drug–drug interactions (DDIs) are common and can result in patient harm. …”
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427
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Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects
Published 2023-02-01Subjects: “…drug interactions…”
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429
Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice
Published 2020-09-01Subjects: “…drug–drug interactions…”
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430
Potentially clinically significant drug-drug interactions in older patients admitted to the hospital: A cross-sectional study
Published 2023-02-01Subjects: Get full text
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431
Assessment of drug–drug interaction potential with EDP‐305, a farnesoid X receptor agonist, in healthy subjects
Published 2022-09-01“…Four studies were conducted in healthy volunteers to evaluate the drug–drug interaction (DDI) potential of EDP‐305 co‐administered with drugs known to be substrates for drug metabolizing enzymes or transporters, and to assess the effect of inhibitors and inducers of CYP3A4 on EDP‐305. …”
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432
Drug Interaction between Dexamethasone and Ketoprofen with Thiopental in Male Dogs: Effect on the Recovery from Anesthesia and Pharmacokinetics Parameters
Published 2022-01-01“…Drug-drug interactions (DDIs) are an important part of clinical veterinary pharmacology. …”
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433
Evaluation and Management of Drug-Drug Interactions in Patients Hospitalized in Nephrology and Post-Transplant Wards in a Teaching Hospital
Published 2020-03-01Subjects: Get full text
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434
Factors associated with a basic common drug-drug interaction knowledge among emergency department medical personnel
Published 2022-10-01Subjects: “…Drug interactions…”
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435
Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat
Published 2024-01-01“…Preclinical studies have demonstrated that the primary route of metabolism for vericiguat is glucuronidation, mainly catalyzed by uridine diphosphate‐glucuronosyltransferase (UGT)1A9 and to a lesser extent UGT1A1. Whereas a drug–drug interaction (DDI) study of the UGT1A9 inhibitor mefenamic acid showed a 20% exposure increase, the effect of UGT1A1 inhibitors has not been assessed clinically. …”
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436
Modulatory Effects of Atractylodin and β-Eudesmol on Human Cytochrome P450 Enzymes: Potential Drug-Drug Interactions
Published 2023-03-01Subjects: Get full text
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437
Evaluation of potential drug-drug interactions in hospitalized patients at a tertiary care hospital: A pilot study
Published 2020-06-01Subjects: Get full text
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438
Islatravir Is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions via Major Drug-Metabolizing Enzymes or Transporters
Published 2021-08-01Subjects: Get full text
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439
Adverse drug reactions and correlations with drug–drug interactions: A retrospective study of reports from 2011 to 2020
Published 2022-08-01Subjects: Get full text
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440
Reporting a lethal drug interaction occurred during evaluation of insulin resistance in mice polycystic ovary model
Published 2018-05-01Subjects: “…Drug interaction…”
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