Metabolites Analysis of Anti-Myocardial Ischemia Active Components of <i>Saussurea involucrata</i> Based on Gut Microbiota—Drug Interaction by Hang Yu, Jie Fu, Hui-Hui Guo, Li-Bin Pan, Hui Xu, Zheng-Wei Zhang, Jia-Chun Hu, Xin-Yu Yang, Hao-Jian Zhang, Meng-Meng Bu, Yuan Lin, Jian-Dong Jiang, Yan Wang

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Risk management strategy for preventing the reduced treatment effectiveness from the position of drug interactions and polypharmacy in patients with coronary heart disease by Anna A. Gruzdeva, Alexander L. Khokhlov, Mikhail V. Ilyin

“…Results and discussion: In these patients, the evaluation of drug interactions revealed 580 variants (48 were dangerous, 428 – significant, 104 – insignificant). …”
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Drug–Drug Interactions and Pharmacogenomic Evaluation in Colorectal Cancer Patients: The New Drug-PIN^® System Comprehensive Approach by Michela Roberto, Alessandro Rossi, Martina Panebianco, Leda Marina Pomes, Giulia Arrivi, Debora Ierinò, Maurizio Simmaco, Paolo Marchetti, Federica Mazzuca

“…Drug–drug interactions (DDIs) can affect both treatment efficacy and toxicity. …”
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Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction by Luna Prieto Garcia, Anna Lundahl, Christine Ahlström, Anna Vildhede, Hans Lennernäs, Erik Sjögren

“…Both platforms predicted equally well the observed simvastatin (lactone and acid) pharmacokinetics (20–80 mg), BCRP and OATP1B1 drug–gene interactions (DGIs), and drug–drug interactions (DDIs) when co‐administered with CYP3A4 and OATP1B1 inhibitors/inducers. …”
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Critical review of radiopharmaceutical-drug interactions, unexpected new age for a Tupiguarani settlement, and the h-index in the Brazilian Academy of Sciences by Alexander W.A. Kellner

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The Contribution of Pharmacogenetic Drug Interactions to 90-Day Hospital Readmissions: Preliminary Results from a Real-World Healthcare System by Sean P. David, Lavisha Singh, Jaclyn Pruitt, Andrew Hensing, Peter Hulick, David O. Meltzer, Peter H. O’Donnell, Henry M. Dunnenberger

“…The presence of at least one pharmacogenetic indicator for a medication prescribed within 30 days of hospital admission was considered a gene-x-drug interaction. Multivariable logistic regression analyzed the association between one or more gene-x-drug interactions with 90-day readmission. …”
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Potential Clinically Relevant Effects of Sialylation on Human Serum AAG-Drug Interactions Assessed by Isothermal Titration Calorimetry: Insight into Pharmacoglycomics? by Robert Kerep, Tino Šeba, Valentina Borko, Tin Weitner, Toma Keser, Gordan Lauc, Mario Gabričević

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Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels by Jéssica Veiga-Matos, Ana I. Morales, Marta Prieto, Fernando Remião, Renata Silva

“…These modulators can act as inhibitors, inducers, or activators, potentially causing drug–drug interactions (DDIs). This comprehensive review explores diverse models and techniques used to assess drug-induced P-gp modulation. …”
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Evaluating the Counseling Standards and Ability of Pharmacy Staff to Detect Antibiotic-Drugs Interactions: A Simulated Client Study from Pakistan by Muhammad Majid Aziz, Muhammad Fawad Rasool, Muteb Alanazi, Tareq Nafea Alharby, Jowaher Alanazi, Bader Huwaimel

“…Scenario2 indicated counseling provision for prescribed antibiotics that have possible antibiotic–drug interactions. The evaluation of counseling skills was also conducted. …”
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A Shared Decision-making Tool for Drug Interactions Between Warfarin and Nonsteroidal Anti-inflammatory Drugs: Design and Usability Study by Thomas J Reese, Guilherme Del Fiol, Keaton Morgan, Jason T Hurwitz, Kensaku Kawamoto, Ainhoa Gomez-Lumbreras, Mary L Brown, Henrik Thiess, Sara R Vazquez, Scott D Nelson, Richard Boyce, Daniel Malone

“… BackgroundExposure to life-threatening drug-drug interactions (DDIs) occurs despite the widespread use of clinical decision support. …”
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Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug–drug interaction studies by Jayaprakasam Bolleddula, Sathej Gopalakrishnan, Ping Hu, Jennifer Dong, Karthik Venkatakrishnan

“…Hence, rifampicin is used extensively in clinical studies to assess drug–drug interactions (DDIs). Despite NA impurities being reported in rifampicin and rifapentine above the acceptable limits, these critical anti‐infective drugs are available for therapeutic use considering their benefit–risk profile. …”
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Opioid Use Disorders in People Living with HIV/AIDS: A Review of Implications for Patient Outcomes, Drug Interactions, and Neurocognitive Disorders by Alina Cernasev, Michael P. Veve, Theodore J. Cory, Nathan A. Summers, Madison Miller, Sunitha Kodidela, Santosh Kumar

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Randomized prospective trial to detect and distinguish between medication nonadherence, drug-drug interactions, and disease progression in chronic cardiometabolic disease by John W Peabody, Divya Ganesan, Czarlota Valdenor, David Paculdo, Joshua Schrecker, Christopher Westerfield, Rebecca Heltsley

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Opioid analgesics-related pharmacokinetic drug interactions: from the perspectives of evidence based on randomized controlled trials and clinical risk management by Feng XQ, Zhu LL, Zhou Q

Subjects: “…drug-drug interactions…”
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Beverage–Drug Interaction: Effects of Green Tea Beverage Consumption on Atorvastatin Metabolism and Membrane Transporters in the Small Intestine and Liver of Rats by Hsien-Tsung Yao, Ya-Ru Hsu, Mei-Ling Li

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Drug–Drug Interactions with Oral Anticoagulants as Potentially Inappropriate Medications: Prevalence and Outcomes in Elderly Patients in Primary Care and Hospital Settings by Mathilde Bories, Guillaume Bouzillé, Marc Cuggia, Pascal Le Corre

Subjects: “…drug–drug interactions…”
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A Drug&ndash;Drug Interaction Study to Evaluate the Impact of Simvastatin and Itraconazole on Erlotinib Pharmacokinetics in Rats by UPLC-MS/MS by Fan Z, Gao X, Wang M, Tian Z

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PB2219: POLYPHARMACY AND DRUG-TO-DRUG INTERACTIONS MAY HAVE A NEGATIVE EFFECT ON SURVIVAL IN PATIENTS WITH CHRONIC MYELOPROLIFERATIVE NEOPLASMS by Ivan Krecak, Ljerka Pivac, Eva Cubric, Marko Lucijanic, Marko Skelin

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BioChemDDI: Predicting Drug–Drug Interactions by Fusing Biochemical and Structural Information through a Self-Attention Mechanism by Zhong-Hao Ren, Chang-Qing Yu, Li-Ping Li, Zhu-Hong You, Jie Pan, Yong-Jian Guan, Lu-Xiang Guo

Subjects: “…drug–drug interactions…”
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Five-Year Trends in Potential Drug Interactions with Direct-Acting Oral Anticoagulants in Patients with Atrial Fibrillation: An Australian-Wide Study by Woldesellassie M. Bezabhe, Luke R. Bereznicki, Jan Radford, Barbara C. Wimmer, Mohammed S. Salahudeen, Ivan Bindoff, Edward Garrahy, Gregory M. Peterson

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