Detection of potential drug-drug interactions among ovarian cancer patients in a tertiary care teaching hospital in South India- A retrospective approach by Kala Bahadur Rawal, Uday Venkat Mateti, Vijith Shetty, M.K. Unnikrishnan, C.S. Shastry

Subjects: “…Drug-interactions…”
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Individual Pharmacotherapy Management (IPM)—IV: Optimized Usage of Approved Antimicrobials Addressing Under-Recognized Adverse Drug Reactions and Drug-Drug Interactions in Polypharmacy by Ursula Wolf, Henning Baust, Rüdiger Neef, Thomas Steinke

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Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL−35 by Chengming Wen, Haoyang Hu, Wenwen Zhang, Xin Liu, Xuehua Jiang, Ling Wang

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Recent Advances in Synthetic Drugs and Natural Actives Interacting with OAT3 by Ying Chen, Hongyan Li, Ke Wang, Yousheng Wang

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P586: POTENTIAL DRUG-DRUG INTERACTIONS OF ANTIFUNGAL PROPHYLAXIS AND MIDOSTAURIN IN FLT3-MUTATED ACUTE MYELOID LEUKEMIA – CLINICAL IMPLICATIONS OF THERAPEUTIC DRUG MONITORING by Carolin Joisten, Carsten Müller, Sibylle Mellinghoff, Christian Maurer, Karl-Anton Kreuzer, Martin Wiesen, Philipp Koehler, Oliver A. Cornely, Jannik Stemler

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Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors by Toshihisa Ishikawa, Shin-ichi Miyatake, Toshihiko Kuroiwa, Shun-ichiro Ogura, Yuichiro Hagiya, Yoshinaga Kajimoto, Naokado Ikeda, Kenkichi Takahashi

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A pharmacoepidemiologic study of drug interactions in a Brazilian teaching hospital Um estudo farmacoepidemiológico de interações medicamentosas em um hospital universitário brasileiro by Joice Mara Cruciol-Souza, João Carlos Thomson

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Interações medicamentosas em prescrições de idosos hipertensos: prevalência e significância clínica [Drug interactions in prescriptions for elderly hypertensive patients: prevalence and clinical significance] by Natália Balera Ferreira Pinto, Liliana Batista Vieira, Fernanda Maria Vieira Pereira, Adriano Max Moreira Reis, Silvia Helena De Bortoli Cassiani

Subjects: “…atenção primária à saúde [drug interactions…”
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Frequency, severity, and factors associated with clinically significant drug-drug interactions among patients with cancer attending Mbarara Regional Referral Hospital Cancer Unit, Uganda by Bonny Luzze, Barnabas Atwiine, Henry Mark Lugobe, Tadele Mekuriya Yadesa

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Identification of Drugs Acting as Perpetrators in Common Drug Interactions in a Cohort of Geriatric Patients from Southern Italy and Analysis of the Gene Polymorphisms That Affect Their Interacting Potential by Mauro Cataldi, Camilla Celentano, Leonardo Bencivenga, Michele Arcopinto, Chiara Resnati, Annalaura Manes, Loreta Dodani, Lucia Comnes, Robert Vander Stichele, Dipak Kalra, Giuseppe Rengo, Francesco Giallauria, Ugo Trama, Nicola Ferrara, Antonio Cittadini, Maurizio Taglialatela

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Simultaneous Pharmacokinetic Evaluation of Pantoprazole and Vitamin B Complex for Assessing Drug–Drug Interactions in Healthy Bangladeshi Adults by a Newly Developed and Validated HPLC Method by Sherejad Sanam, Shimul Halder, S. M. Abdur Rahman

Subjects: “…drug interactions…”
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Drug–drug interaction signals between loop diuretics and teicoplanin during acute kidney injury evaluated using Japanese spontaneous adverse drug event reports by Toshinori Hirai, Yuki Kondo, Yuka Sakazaki, Ayaka Seki, Yoichi Ishitsuka, Takuya Iwamoto

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A Novel Method for Predicting the Human Inherent Clearance and Its Application in the Study of the Pharmacokinetics and Drug–Drug Interaction between Azidothymidine and Fluconazole Mediated by UGT Enzyme by Yawen Yuan, Jun Zhang, Boyu Fang, Xiaoqiang Xiang, Guo Ma, Shunguo Zhang, Bin Zhu, Weimin Cai

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The clinical impact of rifampicin-based anti-TB therapy and tenofovir alafenamide-containing ARV regimen drug Interaction in people living with HIV: Case series report by Yahya Ali Mohzari, Mohammed AL Musawa, Ahmad Alrashed, Bandar Zaeri, Nader Damfu, Peter Cahusac, Sana Alwafai, Ahmad Alamer, Abdulaziz Almulhim

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Role of Persistent Organic Pollutants in Breast Cancer Progression and Identification of Estrogen Receptor Alpha Inhibitors Using In-Silico Mining and Drug-Drug Interaction Network Approaches by Bibi Zainab, Zainab Ayaz, Umer Rashid, Dunia A. Al Farraj, Roua M. Alkufeidy, Fatmah S. AlQahtany, Reem M. Aljowaie, Arshad Mehmood Abbasi

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Bile Acid–Drug Interaction via Organic Anion-Transporting Polypeptide 4C1 Is a Potential Mechanism of Altered Pharmacokinetics of Renally Excreted Drugs by Minami Yamauchi, Toshihiro Sato, Ayana Otake, Masaki Kumondai, Yu Sato, Masafumi Kikuchi, Masamitsu Maekawa, Hiroaki Yamaguchi, Takaaki Abe, Nariyasu Mano

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A Whole-Body Physiologically Based Pharmacokinetic Model Characterizing Interplay of OCTs and MATEs in Intestine, Liver and Kidney to Predict Drug-Drug Interactions of Metformin with Perpetrators by Yiting Yang, Zexin Zhang, Ping Li, Weimin Kong, Xiaodong Liu, Li Liu

Subjects: “…drug–drug interaction (DDI)…”
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Tiered approach to evaluate the CYP3A victim and perpetrator drug–drug interaction potential for vonoprazan using PBPK modeling and clinical data to inform labeling by Darcy J. Mulford, Diane Ramsden, Liming Zhang, Ingrid Michon, Eckhard Leifke, Neila Smith, Hannah M. Jones, Carmelo Scarpignato

“…A tiered approach was applied to understand the CYP3A victim and perpetrator drug–drug interaction (DDI) potential for vonoprazan. Mechanistic static modeling suggested vonoprazan is a potential clinically relevant CYP3A inhibitor. …”
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A comprehensive evaluation in clinic and physiologically‐based pharmacokinetic modeling and simulation to confirm lack of cytochrome P450–mediated drug–drug interaction potential for pomotrelvir by Ziping Yang, Nathalie Rioux, Ludwig Vincent, Hannah M. Jones, David Cha, Andrew Plummer, David Wilfret, Brian P. Kearney

“…Here the cytochrome P450 (CYP)–mediated drug–drug interaction (DDI) potential of pomotrelvir was evaluated for major CYP isoforms, starting with in vitro assays followed by the basic static model assessment. …”
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Cenobamate as add-on therapy for drug resistant epilepsies: effectiveness, drug to drug interactions and neuropsychological impact. What have we learned from real word evidence? by Nicola Pietrafusa, Giovanni Falcicchio, Emilio Russo, Simona Lattanzi, Bianca Goffredo, Raffaele Simeoli, Sara Cairoli, Tiziana Corsetti, Roberta Roberti, Marina De Tommaso, Federico Vigevano, Angela La Neve, Nicola Specchio

“…Plasma levels measurements confirm that CNB acts both as “victim” and as “perpetrator” of drug-drug interactions.…”
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