Status Epilepticus in the Elderly by Lu-An Chen, Shuo-Bin Jou

“…The newer intravenous antiepileptic drugs, which have fewer adverse effects and drug interactions, appear to be reasonable treatment options for elderly patients. …”
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A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer. by Muellner, M, Uras, I, Gapp, B, Kerzendorfer, C, Smida, M, Lechtermann, H, Craig-Mueller, N, Colinge, J, Duernberger, G, Nijman, S

“…However, there has been no systematic approach for analyzing gene-drug interactions in human cells. Here we establish a multiplexed assay to study the cellular fitness of a panel of engineered isogenic cancer cells in response to a collection of drugs, enabling the systematic analysis of thousands of gene-drug interactions. …”

Clinical safety and tolerability issues in use of triazole derivatives in management of fungal infections by Dionissios Neofytos, Edina Avdic, Anna-Pelagia Magiorakos

“…Moreover, knowledge of the drug–drug interactions and potential toxicities of each agent is critical prior to administering a triazole. …”
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Machine learning and structure-based modeling for the prediction of UDP-glucuronosyltransferase inhibition by Balint Dudas, Youcef Bagdad, Milan Picard, David Perahia, Maria A. Miteva

“…Strong inhibition of UGT1A1 may trigger adverse drug/herb-drug interactions, or result in disorders of endobiotic metabolism. …”
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Current and future use of colchicine in patients with COVID-19 by Yu. Yu. Kiselev, A. V. Matveev, D. A. Sychev

“…If prescribing colchicine, the one should perform clinical and hematological monitoring and avoid drug interactions.…”
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Epilepsy in the Elderly by Lu-An Chen, Shih-Jung Cheng, Shuo-Bin Jou

“…Decision-making for AED choice depends on many different factors, including pharmacological properties, efficacy, tolerability from side effects, drug interactions, and medical comorbidities. The newer AEDs with lesser adverse effects and fewer drug interactions appear to be reasonable treatment options for elderly patients. …”
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The use of telaprevir for the treatment of hepatitis C in patients undergoing liver transplantation (Literature review and clinical experience) by M. Sh. Khubutiya, V. E. Syutkin, N. I. Geyvandova, A. A. Salienko, T. V. Gudzovskaya, M. S. Novruzbekov

“…Efficacy and adverse events have been analyzed with peculiar attention to drug-drug interactions between calcineurin inhibitors and HCV protease inhibitors. …”
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Hyperkalemia: A persisting risk. A case report and update on current management by Sebastian Schnaubelt, Jan Niederdoeckl, Christian Schoergenhofer, Filippo Cacioppo, Nikola Schuetz, Alexander O. Spiel, Manfred Hecking, Hans Domanovits

“…Potentially life‐threatening hyperkalemia is often induced by drug interactions. ECG features may be crucial for diagnosis, and treatment depends on setting and resources.…”
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Knowledge, Attitude and Performance of Community Pharmacists towards Prescriptions in Mazandaran Province, Iran by Mohammad Eslamijouybari, Mina Amini, Zeinab Esfahani, Atefeh Asadollahpour, Saba Hosseini, Mohammad Hossein Hosseinzadeh

“…Conclusion: At the community pharmacy, pharmacists usually focus on dispensing correct medication and pay less attention to pharmacy counseling. Trainings on drug interactions and adverse drug reactions could increase the awareness and knowledge of pharmacists.…”
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Drug Thrombus Resulting in Superior Vena Cava Syndrome: A Case Report by Vanstraelen Stijn, Vandenbrande Jeroen, Yilmaz Alaaddin

“…Superior vena cava syndrome is one of the more serious complications of central venous catheter insertion. Drug interactions of administered drugs used in association with these catheters can lead to formation of precipitations and consequently thrombus formation. …”
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Pharmacist interventions for appropriate COVID-19 antiviral therapy in long-term care facilities: A public health initiative by Jenna Preusker, Daniel Schroeder, Scott Bergman, Mark Rupp, Brandon Scott, Trevor Van Schooneveld, Andrew Watkins, Matthew Donahue, Muhammad Salman Ashraf

“…An ASAP pharmacist reviewed each survey submission for renal and hepatic function, drug–drug interactions, date of symptom onset, and ability to take oral medications. …”
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Drug cocktail optimization in chemotherapy of cancer. by Saskia Preissner, Mathias Dunkel, Michael F Hoffmann, Sarah C Preissner, Nikolai Genov, Wen Wei Rong, Robert Preissner, Karlheinz Seeger

“…OBJECTIVE: The aim of this work was to find drug interactions and to avoid side effects or ineffective therapy in chemotherapy. …”
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Estratégias terapêuticas em epilepsia. by J Pimentel

“…With the advances in the so-called classic antiepileptic drugs (AED)--carbamazepine, phenobarbital, phenytoin and valproate--monotherapy has become the most popular strategy for the treatment of epilepsies, based on their unquestionable clinical efficacy and on frequent drug interactions and teratogenesis caused by polypharmacy. …”
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The Importance of Pharmaceutical Dosage Forms in Administration via Enteral Feeding Tubes by Kutay Demirkan, Aygin Bayraktar Ekincioğlu

“…The risk of the drug interactions arises in patients who have nutritional support. …”
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Natural products in drug discovery: meeting the urgency for new antimicrobials for human and veterinary use by Marcus Vinícius Dias-Souza, Arthur Azevedo Perpétuo, Gabriel Souza dos Santos, Luiz Felipe Carreiro Machado, Renan Martins dos Santos

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Evaluasi Data Peresepan Elektronik di Pu skesmas Gunung Kidul Tahun 2011 by , Zakiyah Oktafiani, , dr. Lutfan Lazuardi, M.Kes, PhD

“…Duplication of therapy in prescribing occurred in 15 recipes. Drug interactions occur in 48 recipes. Evaluation of the results of the overall prescribing see a trend in the use of drugs known as corticosteroids.…”

PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY by , Elena Yustina, S.T., , Prof. Drs. Subanar, Ph.D

“…Drug interactions is the interaction occurs between drugs that consumption simultaneously. …”

Evaluation of the Expression Profile of Irinotecan-Induced Diarrhea in Patients with Colorectal Cancer by Mashiro Okunaka, Daisuke Kano, Reiko Matsui, Toshikatsu Kawasaki, Yoshihiro Uesawa

“…Firstly, we searched for suspected drugs related to the occurrence of diarrhea using reported odds ratio and calculated the signal score to assess drug–drug interactions. Subsequently, we conducted a time-to-onset analysis using Weibull distribution. …”
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Pharmacokinetic Pharmacodynamic Modelling Contributions to Improve Paediatric Anaesthesia Practice by James D. Morse, Luis Ignacio Cortinez, Brian J. Anderson

“…Quantification of drug interactions has improved the understanding of the effects of drug combinations. …”
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Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition by Yaochen Xie, Qian Zhou, Qiaojun He, Xiaoyi Wang, Jincheng Wang

“…This review may facilitate clinical decision making based on patients' physical conditions and the avoidance of drug–drug interactions. Moreover, the identification and development of novel drugs with appropriate physiological dispositions might be inspired.…”
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