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1701
Status Epilepticus in the Elderly
Published 2016-03-01“…The newer intravenous antiepileptic drugs, which have fewer adverse effects and drug interactions, appear to be reasonable treatment options for elderly patients. …”
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1702
A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.
Published 2011“…However, there has been no systematic approach for analyzing gene-drug interactions in human cells. Here we establish a multiplexed assay to study the cellular fitness of a panel of engineered isogenic cancer cells in response to a collection of drugs, enabling the systematic analysis of thousands of gene-drug interactions. …”
Journal article -
1703
Clinical safety and tolerability issues in use of triazole derivatives in management of fungal infections
Published 2010-04-01“…Moreover, knowledge of the drug–drug interactions and potential toxicities of each agent is critical prior to administering a triazole. …”
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1704
Machine learning and structure-based modeling for the prediction of UDP-glucuronosyltransferase inhibition
Published 2022-11-01“…Strong inhibition of UGT1A1 may trigger adverse drug/herb-drug interactions, or result in disorders of endobiotic metabolism. …”
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1705
Current and future use of colchicine in patients with COVID-19
Published 2020-10-01“…If prescribing colchicine, the one should perform clinical and hematological monitoring and avoid drug interactions.…”
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Article -
1706
Epilepsy in the Elderly
Published 2012-06-01“…Decision-making for AED choice depends on many different factors, including pharmacological properties, efficacy, tolerability from side effects, drug interactions, and medical comorbidities. The newer AEDs with lesser adverse effects and fewer drug interactions appear to be reasonable treatment options for elderly patients. …”
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1707
The use of telaprevir for the treatment of hepatitis C in patients undergoing liver transplantation (Literature review and clinical experience)
Published 2016-02-01“…Efficacy and adverse events have been analyzed with peculiar attention to drug-drug interactions between calcineurin inhibitors and HCV protease inhibitors. …”
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1708
Hyperkalemia: A persisting risk. A case report and update on current management
Published 2020-09-01“…Potentially life‐threatening hyperkalemia is often induced by drug interactions. ECG features may be crucial for diagnosis, and treatment depends on setting and resources.…”
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1709
Knowledge, Attitude and Performance of Community Pharmacists towards Prescriptions in Mazandaran Province, Iran
Published 2020-05-01“…Conclusion: At the community pharmacy, pharmacists usually focus on dispensing correct medication and pay less attention to pharmacy counseling. Trainings on drug interactions and adverse drug reactions could increase the awareness and knowledge of pharmacists.…”
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1710
Drug Thrombus Resulting in Superior Vena Cava Syndrome: A Case Report
Published 2020-05-01“…Superior vena cava syndrome is one of the more serious complications of central venous catheter insertion. Drug interactions of administered drugs used in association with these catheters can lead to formation of precipitations and consequently thrombus formation. …”
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1711
Pharmacist interventions for appropriate COVID-19 antiviral therapy in long-term care facilities: A public health initiative
Published 2023-06-01“…An ASAP pharmacist reviewed each survey submission for renal and hepatic function, drug–drug interactions, date of symptom onset, and ability to take oral medications. …”
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1712
Drug cocktail optimization in chemotherapy of cancer.
Published 2012-01-01“…OBJECTIVE: The aim of this work was to find drug interactions and to avoid side effects or ineffective therapy in chemotherapy. …”
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1713
Estratégias terapêuticas em epilepsia.
Published 1997-09-01“…With the advances in the so-called classic antiepileptic drugs (AED)--carbamazepine, phenobarbital, phenytoin and valproate--monotherapy has become the most popular strategy for the treatment of epilepsies, based on their unquestionable clinical efficacy and on frequent drug interactions and teratogenesis caused by polypharmacy. …”
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1714
The Importance of Pharmaceutical Dosage Forms in Administration via Enteral Feeding Tubes
Published 2016-04-01“…The risk of the drug interactions arises in patients who have nutritional support. …”
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Article -
1715
Natural products in drug discovery: meeting the urgency for new antimicrobials for human and veterinary use
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Article -
1716
Evaluasi Data Peresepan Elektronik di Pu skesmas Gunung Kidul Tahun 2011
Published 2013“…Duplication of therapy in prescribing occurred in 15 recipes. Drug interactions occur in 48 recipes. Evaluation of the results of the overall prescribing see a trend in the use of drugs known as corticosteroids.…”
Thesis -
1717
PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
Published 2012“…Drug interactions is the interaction occurs between drugs that consumption simultaneously. …”
Thesis -
1718
Evaluation of the Expression Profile of Irinotecan-Induced Diarrhea in Patients with Colorectal Cancer
Published 2021-04-01“…Firstly, we searched for suspected drugs related to the occurrence of diarrhea using reported odds ratio and calculated the signal score to assess drug–drug interactions. Subsequently, we conducted a time-to-onset analysis using Weibull distribution. …”
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1719
Pharmacokinetic Pharmacodynamic Modelling Contributions to Improve Paediatric Anaesthesia Practice
Published 2022-05-01“…Quantification of drug interactions has improved the understanding of the effects of drug combinations. …”
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1720
Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition
Published 2023-06-01“…This review may facilitate clinical decision making based on patients' physical conditions and the avoidance of drug–drug interactions. Moreover, the identification and development of novel drugs with appropriate physiological dispositions might be inspired.…”
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