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1721
Management of Antiretroviral Therapy with Boosted Protease Inhibitors—Darunavir/Ritonavir or Darunavir/Cobicistat
Published 2021-03-01“…The potential of clinically significant drug interactions in patients taking COBI or RTV is high due to the potent inhibitory effect on cytochrome CYP 450, which attracts significant changes in the pharmacokinetics of PIs. …”
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1722
Descriptors of Cytochrome Inhibitors and Useful Machine Learning Based Methods for the Design of Safer Drugs
Published 2021-05-01“…Drug–drug interactions commonly arise from major cytochrome P450 (CYP) inhibition. …”
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1723
COMORBID PATIENT IN GASTROENTEROLOGY: INDIVIDUAL APPROACH
Published 2018-03-01“…The rationale for the replacement of proton pump inhibitors is given, taking into account the probability of inter-drug interactions in a patient with high cardiovascular risk taking acetylsalicylic acid and having a high risk of gastrointestinal tract bleeding. …”
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1724
Kidney Drug Transporters in Pharmacotherapy
Published 2023-02-01“…The kidney tubule epithelia cells express membrane carriers and transporters, which play an important role in drug elimination, and can determine drug nephrotoxicity and drug–drug interactions, as well as constituting direct drug targets. …”
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1725
Off-label antipsychotics prescription to adolescents with acute psychotic episodes does not cause adverse drug reactions
Published 2021-06-01“…However, an increase in potentially dangerous drug interactions and prescriptions with duplicates drug classes frequency could be considered red flags. …”
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1726
Dolutegravir‐induced acquired sideroblastic anemia in a HIV positive patient: A challenging hematologic complication
Published 2023-12-01“…Key Clinical Message Dolutegravir, the most recent antiretroviral drug with high efficacy, good tolerability, infrequent drug–drug interactions, and a favorable safety profile has not been reported in current literature as a cause of acquired sideroblastic anemia. …”
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1727
Polypharmacy among the elderly in Hermanos Cruz polyclinic
Published 2019-10-01“…The existence of several diseases generates the consumption of multiple drugs, and therefore polypharmacy and drug interactions.…”
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1728
Medication-Related Problems Identified and Addressed by Pharmacists Dispensing COVID-19 Antivirals at a Community Pharmacy
Published 2023-05-01“…A retrospective review was conducted to assess documented MRPs, including significant drug–drug interactions and inappropriate dosing requiring intervention, for prescriptions dispensed from 9 February 2022 to 29 April 2022. …”
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1729
Diffuse Large B-Cell Lymphoma in the HIV Setting
Published 2023-06-01“…The use of cART during chemotherapy treatment was initially controversial due to the potential risk of adverse drug–drug interactions. However, the availability of current cART regimens with less potential to cause drug interactions and evidence that cART improves survival rates in NHL strongly support the use of cART in PWH with DLBCL. …”
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1730
Isavuconazole for Treating Invasive Mould Disease in Solid Organ Transplant Recipients
Published 2023-12-01“…The clinical responses appeared comparable to that found in other high-risk patient populations. Drug-drug interactions with immunosuppressive agents were manageable after the reduction of tacrolimus and the adjustment of mTOR inhibitors at the beginning of treatment. …”
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1731
Evaluation of Encapsulation Potential of Selected Star-Hyperbranched Polyglycidol Architectures: Predictive Molecular Dynamics Simulations and Experimental Validation
Published 2023-10-01“…Polymers, including non-linear copolymers, have great potential in the development of drug delivery systems with many advantages, but the design requires optimizing polymer–drug interactions. Molecular dynamics (MD) simulations can provide insights into polymer–drug interactions for designing delivery systems, but mimicking formulation processes such as drying is often not included in in silico studies. …”
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1732
Polypharmacy among the elderly in Hermanos Cruz polyclinic
Published 2019-10-01“…The existence of several diseases generates the consumption of multiple drugs, and therefore polypharmacy and drug interactions.…”
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1733
Pharmacogenomics of Dementia: Personalizing the Treatment of Cognitive and Neuropsychiatric Symptoms
Published 2023-11-01“…The therapeutic response to currently available drugs is partially effective in only some individuals, with side effects, drug interactions, intolerance, and non-compliance occurring in the majority of dementia patients. …”
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1734
Precision Medicine & Pharmacogenomics: Personalized Medication in Neuropsychiatric Disorders using AI and telepsychiatry
Published 2022-06-01“…Objectives Determine benefits of pharmacogenomic analysis (PGx) in CNS diseases regarding: - cost effectiveness - adverse drug reactions - reduced hospitalizations -drug interactions - efficacy - quality of life - “trial and error” approach avoidance Methods Questionnaires before and after the treatment provided using PGX tests Telepsychiatry for consultation along face to face sessions were conducted. …”
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1735
Admissions for drug-related problems at the Emergency Department of a University Hospital in the Kingdom of Saudi Arabia
Published 2015-01-01“…Conclusions: Noncompliance to treatment, overdose toxicity, drug interactions, and drug abuse are important causes of hospital admissions as a result of DRPs. …”
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1736
Politerapi dalam manajemen epilepsi.
Published 1997“…This study wanted to remind: what factors should be considered in epilepsy polytherapy. Drug-drug interactions and the risk of side effects might occures. …”
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1737
Effect Of Standardised Methanolic Extract Of Phyllanthus Niruri (Linn.) On Phase I And II Drug Metabolism And Its Molecular Mechanism Elucidation In Rat Liver
Published 2010“…Due to the wide use of herbal medicinal products, the possibilities of herb-drug interactions have increased. Little is known about the incidence and consequences of herb-drug interactions in patients who consume P. niruri concomitantly with other drugs. …”
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1738
Evolving field of cardio-oncology
Published 2023-04-01“…Therapy development for cancer and cardiovascular disease (CVD) to prolong lifespan makes the relationship between these two conditions more complex. Drug interactions in cardiology and oncology are associated with metabolism and drug transportation. …”
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1739
Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
Published 2017-02-01“…Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications, posaconazole is known to have many side effects and drug-drug interactions. We present a patient who developed rhabdomyolysis after being started on posaconazole for prophylaxis in the setting of relapsed acute myeloid leukemia.…”
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1740
Equipping providers to offer novel MPTs: Developing counseling messages for the Dual Prevention Pill in clinical studies and beyond
Published 2023-05-01“…Discontinuation/switching: If you decide to discontinue use of the DPP, but want to be protected from HIV and/or unintended pregnancy, in most cases, you can begin using PrEP or another contraceptive method right away. Drug interactions: There are no drug-drug interactions from combining oral PrEP and COC in the DPP. …”
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