Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions by Helena Leonie Hanae Loer, Denise Feick, Simeon Rüdesheim, Dominik Selzer, Matthias Schwab, Donato Teutonico, Sebastian Frechen, Maaike van derLee, Dirk Jan A. R. Moes, Jesse J. Swen, Thorsten Lehr

“…Furthermore, tacrolimus is highly susceptible to drug–drug interactions, acting as a victim drug when coadministered with CYP3A perpetrators. …”
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Evaluasi Penggunaan Antibiotika Berdasarkan Kontraindikasi, Efek Samping, dan Interaksi Obat pada Pasien Rawat Inap dengan Infeksi Saluran Pernapasan Bawah Di Rumah Sakit Panti Rap... by Fajar Prasetya

“…The results obtained showed that the contraindications and adverse reactions of drugs are not found, the incidence of drug interactions by 22 (16%) of 137 cases and of 29 types of antibiotics are used there are 7 species (24%) of potential antibiotic drug interactions. …”
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Herbal supplement use among reproductive-aged women in an academic infertility practice by Julie Friedman, M.D., Jeanelle Sheeder, M.S.P.H., Ph.D., Aaron Lazorwitz, M.D., M.S.C.S., Alex Joel Polotsky, M.D., M.S.

“…We identified 41 moderate-risk supplement-drug interactions, with 12 of these interactions attributed to infertility therapies. …”
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Prevalence and Associated Factors of Potentially Inappropriate Medication among Elderly Outpatients by DUAN Yanqin, PENG Ying, LIU Shenglan, LIU Haijiao, YANG Huiqiong, HU Haiqing

“…Background China's aging adults are increasing, and have increasing prevalence of multimorbidity and polypharmacy, leading to a high risk of drug-drug interactions and adverse drug reactions. There are few studies on potentially inappropriate medication (PIM) in the elderly, and PIM in this group has not yet received sufficient attention clinically. …”
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A review of common methods to convert morphine to methadone by Eric Wong, Kathryn A. Walker

“…Many authors have discussed important issues surrounding patient selection, drug interactions, screening for QTc prolongation and monitoring. …”
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Doxorubicin Anticancer Drug Monitoring by ds-DNA-Based Electrochemical Biosensor in Clinical Samples by Firouzeh Hassani Moghadam, Mohammad A. Taher, Hassan Karimi-Maleh

“…The molecular docking study revealed that the doxorubicin drug interacted with DNA through intercalation mode, which was in agreement with obtained experimental results. …”
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Therapeutic use of psilocybin: Practical considerations for dosing and administration by Caroline A. MacCallum, Lindsay A. Lo, Carly A. Pistawka, Jagpaul Kaur Deol

“…Within this piece we will review basic psilocybin pharmacology and pharmacokinetics, indications, practical therapeutic strategies (e.g., dosing, administration, monitoring) and safety considerations (e.g., contraindications, adverse events, and drug interactions). With this information, our goal is to increase the knowledge and comfort of health care professionals to discuss and counsel their patients on psilocybin therapy, ultimately improving patient care and safety.…”
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Allergic hypersensitivity to antiretroviral drugs: etravirine, raltegravir and darunavir by Manuel Anastacio Sánchez-Olivas, Martha Patricia Valencia-Zavala, Gloria Bertha Vega-Robledo, Jesús Alberto Sánchez-Olivas, Guillermo Velázquez-Sámano

“…Our aim is to gain a working knowledge of these adverse effects, promoting the early recognition and reversal of potentially serious adverse effects, and reducing the potential for adverse drug interactions.…”
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Equine Drug Transporters: A Mini-Review and Veterinary Perspective by Brielle Rosa

“…Differences in transporter expression cause difficulties in extrapolation of drug pharmacokinetic parameters between species, and lack of knowledge of species-specific transporter distribution and function can lead to drug–drug interactions and adverse effects. Horses are one species in which little is known about drug transport and transporter protein expression. …”
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Proton-pump inhibitors by Vasudevan G. Naidoo

“…Long-term safety concerns and possible drug interactions have led to a more conservative approach to PPI use. …”
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Chronic Pain in the Elderly with Cognitive Decline: A Narrative Review by Luca Cravello, Simona Di Santo, Giustino Varrassi, Dario Benincasa, Paolo Marchettini, Marina de Tommaso, Jacob Shofany, Francesca Assogna, Daniele Perotta, Katie Palmer, Antonella Paladini, Fulvia di Iulio, Carlo Caltagirone

“…Pharmacological treatment should consider physiological changes, high comorbidity and drug interactions that occur frequently in the elderly. …”
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Conventional Antifungals for Invasive Infections Delivered by Unconventional Methods; Aerosols, Irrigants, Directed Injections and Impregnated Cement by Richard H. Drew, John R. Perfect

“…The administration of approved antifungals via unapproved formulations or administration routes (such as aerosol, direct injection, irrigation, topical formulation and antifungal-impregnated orthopedic beads or cement) may be resorted to in an attempt to optimize drug exposure while minimizing toxicities and/or drug interactions associated with conventional (systemic) administrations. …”
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Reproductive issues in women on direct oral anticoagulants by Jan Beyer‐Westendorf, Sandra Marten

“…Advantages of DOAC therapy are fewer food and drug interactions and fixed dosing without routine laboratory monitoring, making DOACs the perfect choice especially for younger patients, in whom the main indication for anticoagulation is prevention and treatment of venous thromboembolism (VTE). …”
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Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia by Mikko Karpale, Janne Hukkanen, Jukka Hakkola

“…Activation of pregnane X receptor (PXR), the major regulator of drug metabolism and molecular mediator of clinically significant drug–drug interactions, has been shown to induce hypercholesterolemia. …”
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Genomic and Epigenomic Characterization of Tumor Organoid Models by Chehyun Nam, Benjamin Ziman, Megha Sheth, Hua Zhao, De-Chen Lin

“…Here, we review recent advances in genomic and epigenomic characterization of tumor organoids and the novel findings obtained, highlight significant progressions achieved in organoid modeling of gene–drug interactions and genotype–phenotype associations, and offer perspectives on future opportunities for organoid modeling in basic and clinical cancer research.…”
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Baricitinib: First Systemic Oral Drug for Alopecia Therapy by Prashant Mishra, Sharmila Sinha, Sandeep Vihan, Navdeep Dahiya, Biju Vasudevan

“…In this review, we aim to summarize the different pharmacokinetic and pharmacodynamics aspects including drug interactions, adverse effects/black box warnings and their clinical relevance. …”
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Investigation of Drugs’ Adsorption by the Perfluorane by N. N. Pshenkina, O. M Veselova, Ye. V. Murzina, G. A. Sofronov

“…Key words: perfluorane, binding, drugs, drug interactions.…”
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Brazilian Protocol for Sexually Transmitted Infections, 2020: HIV infection in adolescents and adults by Lauro Ferreira da Silva Pinto Neto, Filipe de Barros Perini, Mayra Gonçalves Aragón, Marcelo Araújo Freitas, Angélica Espinosa Miranda

“…Lately, it has been simplified with more tolerable first-line medications and fewer drug interactions, making its management easy to implement, including by primary health care.…”
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Management of Patients Treated with Direct Oral Anticoagulants in Clinical Practice and Challenging Scenarios by Fabiana Lucà, Fabrizio Oliva, Maurizio Giuseppe Abrignani, Stefania Angela Di Fusco, Iris Parrini, Maria Laura Canale, Simona Giubilato, Stefano Cornara, Martina Nesti, Carmelo Massimiliano Rao, Andrea Pozzi, Giulio Binaghi, Alessandro Maloberti, Roberto Ceravolo, Irma Bisceglia, Roberta Rossini, Pier Luigi Temporelli, Antonio Francesco Amico, Raimondo Calvanese, Sandro Gelsomino, Carmine Riccio, Massimo Grimaldi, Furio Colivicchi, Michele Massimo Gulizia

“…Although DOACs represent a more suitable option, several issues should be considered in clinical practice, including drug–drug interactions (DDIs), switching to other antithrombotic therapies, preprocedural and postprocedural periods, and the use in patients with chronic renal and liver failure and in those with cancer. …”
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Infective Endocarditis in the Elderly: Challenges and Strategies by Carlos Bea, Sara Vela, Sergio García-Blas, Jose-Angel Perez-Rivera, Pablo Díez-Villanueva, Ana Isabel de Gracia, Eladio Fuertes, Maria Rosa Oltra, Ana Ferrer, Andreu Belmonte, Enrique Santas, Mauricio Pellicer, Javier Colomina, Alberto Doménech, Vicente Bodi, Maria José Forner, Francisco Javier Chorro, Clara Bonanad

“…Antibiotic treatment should prioritize diminishing adverse effects and drug interactions while maintaining the best efficacy, as surgical treatment is less commonly performed in this population due to the high surgical risk. …”
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