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1881
Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions
Published 2023-05-01“…Furthermore, tacrolimus is highly susceptible to drug–drug interactions, acting as a victim drug when coadministered with CYP3A perpetrators. …”
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1882
Evaluasi Penggunaan Antibiotika Berdasarkan Kontraindikasi, Efek Samping, dan Interaksi Obat pada Pasien Rawat Inap dengan Infeksi Saluran Pernapasan Bawah Di Rumah Sakit Panti Rap...
Published 2011-06-01“…The results obtained showed that the contraindications and adverse reactions of drugs are not found, the incidence of drug interactions by 22 (16%) of 137 cases and of 29 types of antibiotics are used there are 7 species (24%) of potential antibiotic drug interactions. …”
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1883
Herbal supplement use among reproductive-aged women in an academic infertility practice
Published 2023-03-01“…We identified 41 moderate-risk supplement-drug interactions, with 12 of these interactions attributed to infertility therapies. …”
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1884
Prevalence and Associated Factors of Potentially Inappropriate Medication among Elderly Outpatients
Published 2023-11-01“…Background China's aging adults are increasing, and have increasing prevalence of multimorbidity and polypharmacy, leading to a high risk of drug-drug interactions and adverse drug reactions. There are few studies on potentially inappropriate medication (PIM) in the elderly, and PIM in this group has not yet received sufficient attention clinically. …”
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1885
A review of common methods to convert morphine to methadone
Published 2013-01-01“…Many authors have discussed important issues surrounding patient selection, drug interactions, screening for QTc prolongation and monitoring. …”
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1886
Doxorubicin Anticancer Drug Monitoring by ds-DNA-Based Electrochemical Biosensor in Clinical Samples
Published 2021-07-01“…The molecular docking study revealed that the doxorubicin drug interacted with DNA through intercalation mode, which was in agreement with obtained experimental results. …”
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1887
Therapeutic use of psilocybin: Practical considerations for dosing and administration
Published 2022-12-01“…Within this piece we will review basic psilocybin pharmacology and pharmacokinetics, indications, practical therapeutic strategies (e.g., dosing, administration, monitoring) and safety considerations (e.g., contraindications, adverse events, and drug interactions). With this information, our goal is to increase the knowledge and comfort of health care professionals to discuss and counsel their patients on psilocybin therapy, ultimately improving patient care and safety.…”
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1888
Allergic hypersensitivity to antiretroviral drugs: etravirine, raltegravir and darunavir
Published 2015-04-01“…Our aim is to gain a working knowledge of these adverse effects, promoting the early recognition and reversal of potentially serious adverse effects, and reducing the potential for adverse drug interactions.…”
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1889
Equine Drug Transporters: A Mini-Review and Veterinary Perspective
Published 2020-11-01“…Differences in transporter expression cause difficulties in extrapolation of drug pharmacokinetic parameters between species, and lack of knowledge of species-specific transporter distribution and function can lead to drug–drug interactions and adverse effects. Horses are one species in which little is known about drug transport and transporter protein expression. …”
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1890
Proton-pump inhibitors
Published 2015-05-01“…Long-term safety concerns and possible drug interactions have led to a more conservative approach to PPI use. …”
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1891
Chronic Pain in the Elderly with Cognitive Decline: A Narrative Review
Published 2019-01-01“…Pharmacological treatment should consider physiological changes, high comorbidity and drug interactions that occur frequently in the elderly. …”
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1892
Conventional Antifungals for Invasive Infections Delivered by Unconventional Methods; Aerosols, Irrigants, Directed Injections and Impregnated Cement
Published 2022-02-01“…The administration of approved antifungals via unapproved formulations or administration routes (such as aerosol, direct injection, irrigation, topical formulation and antifungal-impregnated orthopedic beads or cement) may be resorted to in an attempt to optimize drug exposure while minimizing toxicities and/or drug interactions associated with conventional (systemic) administrations. …”
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1893
Reproductive issues in women on direct oral anticoagulants
Published 2021-05-01“…Advantages of DOAC therapy are fewer food and drug interactions and fixed dosing without routine laboratory monitoring, making DOACs the perfect choice especially for younger patients, in whom the main indication for anticoagulation is prevention and treatment of venous thromboembolism (VTE). …”
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1894
Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia
Published 2022-01-01“…Activation of pregnane X receptor (PXR), the major regulator of drug metabolism and molecular mediator of clinically significant drug–drug interactions, has been shown to induce hypercholesterolemia. …”
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1895
Genomic and Epigenomic Characterization of Tumor Organoid Models
Published 2022-08-01“…Here, we review recent advances in genomic and epigenomic characterization of tumor organoids and the novel findings obtained, highlight significant progressions achieved in organoid modeling of gene–drug interactions and genotype–phenotype associations, and offer perspectives on future opportunities for organoid modeling in basic and clinical cancer research.…”
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1896
Baricitinib: First Systemic Oral Drug for Alopecia Therapy
Published 2022-10-01“…In this review, we aim to summarize the different pharmacokinetic and pharmacodynamics aspects including drug interactions, adverse effects/black box warnings and their clinical relevance. …”
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1897
Investigation of Drugs’ Adsorption by the Perfluorane
Published 2011-04-01“…Key words: perfluorane, binding, drugs, drug interactions.…”
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1898
Brazilian Protocol for Sexually Transmitted Infections, 2020: HIV infection in adolescents and adults
Published 2021-05-01“…Lately, it has been simplified with more tolerable first-line medications and fewer drug interactions, making its management easy to implement, including by primary health care.…”
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1899
Management of Patients Treated with Direct Oral Anticoagulants in Clinical Practice and Challenging Scenarios
Published 2023-09-01“…Although DOACs represent a more suitable option, several issues should be considered in clinical practice, including drug–drug interactions (DDIs), switching to other antithrombotic therapies, preprocedural and postprocedural periods, and the use in patients with chronic renal and liver failure and in those with cancer. …”
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1900
Infective Endocarditis in the Elderly: Challenges and Strategies
Published 2022-06-01“…Antibiotic treatment should prioritize diminishing adverse effects and drug interactions while maintaining the best efficacy, as surgical treatment is less commonly performed in this population due to the high surgical risk. …”
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