Interaction between Chinese medicine and digoxin: Clinical and research update by Wei Zhuang, Tao He, Bei-Bei Jia, Zhi-Zhou Wang, Lan Zhang, Xian-Zhe Dong, Sheng-Yan Xi

“…It is often used in combination with other drugs, but drug interactions have a great impact on the plasma concentration of digoxin and lead to adverse reactions (ADRs), such as poisoning. …”
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Patients’ Pharmacogenetic Characteristics and the Risk of Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Cases by A. S. Zhiryakova, N. P. Denisenko, A. V. Kryukov, K. A. Akmalova, S. N. Tuchkova, K. B. Mirzaev, D. A. Sychev

“…To reduce the risk of nephrotoxicity and gastrointestinal bleeding in patients when prescribing ketorolac, healthcare providers should strictly follow the recommended dosing regimen and consider individual comorbidities and potential drug interactions that may potentiate adverse drug reactions. …”
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A pharmacovigilance Study on Critically Ill Patients Admitted In Beni-Suef University Teaching Hospital. by Alshimaa Mohamed Abdelmohymen, Fatma Abdel Haleem Mahmoud, Eman Hassan Nadwa, Abdalaziz Mostafa Ahmed

“…Patients who experienced drug related problems in the form of ADRs and/or adverse drug-drug interactions (DDIs) were recorded. The ADRs were analyzed regarding the incidence (88%), factors affecting the incidence, characteristics (most of ADRs were moderate, preventable, probable and type "A"). …”
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Pharmacomicrobiomics in Anticancer Therapies: Why the Gut Microbiota Should Be Pointed Out by Gabriele Conti, Federica D’Amico, Marco Fabbrini, Patrizia Brigidi, Monica Barone, Silvia Turroni

“…In recent years, microbiota–drug interactions have been extensively investigated, but most of the underlying molecular mechanisms still remain unclear. …”
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Targeting Platelet Activation Pathways to Limit Tumour Progression: Current State of Affairs by Kutlwano R. Xulu, Tanya N. Augustine

“…Published data suggested a cautionary tale in ensuring we adequately investigate not only drug–drug interactions but also those unforeseen reciprocal interactions between drugs and their targets within the tumour microenvironment that may act as selective pressures, enhancing tumour survival and progression.…”
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Optimal Use of Proton Pump Inhibitors and Potassium-competitive Acid Blockers by Jong Kyu Park

“…Indications vary based on the various types and dosages of PPIs and PCABs, and several factors, including patients’ underlying disease, safety profile, particularly with regard to drug-drug interactions, and types of formulations of PPIs and PCABs need to be considered prior to prescribing these medications. …”
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Diabetic Kidney Disease in Post-Transplant Diabetes Mellitus: Causes, Treatment and Outcomes by Lee-Moay Lim, Jer-Ming Chang, Hung-Tien Kuo

“…The therapeutic options are discussed regarding their safety and potential drug–drug interactions with immunosuppressive agents.…”
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The effects of cyclosporine A or activated charcoal co-administration on the pharmacokinetics of enrofloxacin in chickens by Tsvetelina Petkova, Aneliya Milanova, Błażej Poźniak

“…The data suggest a role of efflux transporter proteins in the pharmacokinetics of drugs in chickens and drug-drug interactions have to be considered when substrates and modulators of these transporters are co-administered.…”
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Role of Vitamin D in Childhood Epilepsy by Ahmed El-Abd Ahmed, Mohammed H. Hassan, Asmaa G. Mostafa *, Ali Helmi Bakry

“…The aim of this review: is to evaluate the roleof vitamin D in childhood epilepsy and to study the vitamin D –antiepleptic drugs interactions among epileptic children. Conclusion: vitamin D insufficiency and deficiency are highly prevalent among children with epilepsy.A lot of antiepileptic drugs lower vitamin D level and lead to more seizures specially enzyme inducers' drugs.…”
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Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections by Arturo Sánchez, Susana P. Mejía, Jahir Orozco

“…PNs offer opportunities for preventing unwanted drug interactions and degradation before reaching the target cell of tissue and thus decreasing the development of resistance in microorganisms. …”
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Technology for the treatment promotion of adults living with HIV: Positive o Cuidado (Positive the Care) by Vivian Costa Fermo, Francis Solange Vieira Tourinho, Douglas Dyllon Jerônimo de Macedo, Thaís Favero Alves

“…Results: it was developed the responsive website Positive Care (Positive o Cuidado), composed of an initial presentation screen and 13 other screens named: Family Health and You; Undetectable = Untransmissible; Antiretroviral Drugs; Routine Tests; Vaccination; Antiretroviral Delivery; Drug Interactions; Combined Prevention; Support Services; Healthy Life; Family and Reproductive Planning; Covid 19; and Questions, Curiosities, and Myths. …”
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Visual symptoms with Sofosbuvir in hepatitis C treatment — a case report from Pakistan by Aliya Hasnain, Sabeen Shah, Lindsay Hampejskova

“…It has shown high efficacy in combination with several other drugs with low toxicity, a high resistance barrier, and minimal drug interactions with other hepatitis C DAA drugs. We describe a first of its kind case from Pakistan with visual disturbances caused by Sofosbuvir. …”
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Natural Health Products (NHP’s) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends... by Benjamin Scaria, Siddhartha Sood, Christopher Raad, Jana Khanafer, Rahul Jayachandiran, Alaina Pupulin, Sahibjot Grewal, Michael Okoko, Mansi Arora, Lauren Miles, Siyaram Pandey

“…An additional area for further research is the investigation of drug–drug interactions between NHP’s and chemotherapeutics. …”
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Cardiovascular implications of the COVID-19: Management of complications and drug safety concerns by Maliheh Hamidian, Ramin Ansari, Mohammad Mehdi Zarshenas, Farzaneh Foroughinia

“…This review provides an overview of evidence-based data of CV complications of COVID-19, focusing on their management strategies, as well as potential cardiac adverse effects and drug interactions, due to off-label and investigational drugs used for the treatment of COVID-19.…”
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Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Use for Atherogenic Dyslipidemia in Solid Organ Transplant Patients by Gianluigi Cuomo, Giuseppe Cioffi, Anna Di Lorenzo, Francesca Paola Iannone, Giuseppe Cudemo, Anna Maria Iannicelli, Mario Pacileo, Antonello D’Andrea, Carlo Vigorito, Gabriella Iannuzzo, Francesco Giallauria

“…In transplant patients, these drugs are still poorly used, despite having comparable efficacy to the general population and giving fewer drug interactions with immunosuppressants. Furthermore, there is enough evidence that PCSK9 also plays a role in other pathways, such as inflammation, which is particularly dangerous for graft survival. …”
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Drug-induced QT interval prolongation in cancer patients by Torben K. Becker, Sai-Ching J. Yeung

“…Multiple risk factors and drug–drug interactions increase this risk for dangerous arrhythmias. …”
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Glycaemic Control in Patients Undergoing Percutaneous Coronary Intervention: What Is the Role for the Novel Antidiabetic Agents? <i>A Comprehensive Review of Basic Science and Clin... by Annunziata Nusca, Francesco Piccirillo, Federico Bernardini, Aurelio De Filippis, Federica Coletti, Fabio Mangiacapra, Elisabetta Ricottini, Rosetta Melfi, Paolo Gallo, Valeria Cammalleri, Nicola Napoli, Gian Paolo Ussia, Francesco Grigioni

“…We summarize existing evidence on the effects of these drugs in the setting of PCI, addressing pre-clinical and clinical studies and drug-drug interactions with antiplatelet agents, thus highlighting new opportunities for optimal long-term management of these patients.…”
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The Relationship between Hydrophobicity and Drug-Protein Binding in Human Serum Albumin: A Quartz Crystal Microbalance Study by Ahmad R. Alhankawi, Jacob K. Al-Husseini, Archie Spindler, Clark Baker, Tonderai T. Shoniwa, Mohammed Ahmed, Peter A. Chiarelli, Malkiat S. Johal

“…In this paper, the quartz crystal microbalance with dissipation monitoring (QCM-D) was used to investigate hydrophobicity and binding strength (K_D) for 10 different drugs interacting with human serum albumin (HSA). Quantitative structure activity relationship (QSAR) analysis was used to determine the relationship between drug hydrophobicity (ClogP) and HSA binding strength log(1/K_D). …”
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Pulmonary aspergillosis: diagnosis and treatment by Frederic Lamoth, Thierry Calandra

“…The management of pulmonary aspergillosis is complicated by the limited number of treatment options, drug interactions, adverse events and the emergence of antifungal resistance.…”
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Massive hemoptysis in pregnancy due to invasive pulmonary aspergillosis with pulmonary tuberculosis co‐infection by Nurul Aisyah Abd Rahman, Boon Hau Ng, Nik Nuratiqah Nik Abeed, Muhammad Ishamuddin Ismail, Mohamed Faisal Abdul Hamid, Andrea Ban Yu‐Lin

“…Both mother and baby survived, remaining well at a 6‐week follow‐up, emphasizing the complexities of managing recurrent hemoptysis during pregnancy and potential drug interactions.…”
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