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1921
Interaction between Chinese medicine and digoxin: Clinical and research update
Published 2023-02-01“…It is often used in combination with other drugs, but drug interactions have a great impact on the plasma concentration of digoxin and lead to adverse reactions (ADRs), such as poisoning. …”
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1922
Patients’ Pharmacogenetic Characteristics and the Risk of Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Cases
Published 2022-03-01“…To reduce the risk of nephrotoxicity and gastrointestinal bleeding in patients when prescribing ketorolac, healthcare providers should strictly follow the recommended dosing regimen and consider individual comorbidities and potential drug interactions that may potentiate adverse drug reactions. …”
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1923
A pharmacovigilance Study on Critically Ill Patients Admitted In Beni-Suef University Teaching Hospital.
Published 2021-06-01“…Patients who experienced drug related problems in the form of ADRs and/or adverse drug-drug interactions (DDIs) were recorded. The ADRs were analyzed regarding the incidence (88%), factors affecting the incidence, characteristics (most of ADRs were moderate, preventable, probable and type "A"). …”
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1924
Pharmacomicrobiomics in Anticancer Therapies: Why the Gut Microbiota Should Be Pointed Out
Published 2022-12-01“…In recent years, microbiota–drug interactions have been extensively investigated, but most of the underlying molecular mechanisms still remain unclear. …”
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1925
Targeting Platelet Activation Pathways to Limit Tumour Progression: Current State of Affairs
Published 2022-12-01“…Published data suggested a cautionary tale in ensuring we adequately investigate not only drug–drug interactions but also those unforeseen reciprocal interactions between drugs and their targets within the tumour microenvironment that may act as selective pressures, enhancing tumour survival and progression.…”
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1926
Optimal Use of Proton Pump Inhibitors and Potassium-competitive Acid Blockers
Published 2023-09-01“…Indications vary based on the various types and dosages of PPIs and PCABs, and several factors, including patients’ underlying disease, safety profile, particularly with regard to drug-drug interactions, and types of formulations of PPIs and PCABs need to be considered prior to prescribing these medications. …”
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1927
Diabetic Kidney Disease in Post-Transplant Diabetes Mellitus: Causes, Treatment and Outcomes
Published 2023-02-01“…The therapeutic options are discussed regarding their safety and potential drug–drug interactions with immunosuppressive agents.…”
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1928
The effects of cyclosporine A or activated charcoal co-administration on the pharmacokinetics of enrofloxacin in chickens
Published 2023-01-01“…The data suggest a role of efflux transporter proteins in the pharmacokinetics of drugs in chickens and drug-drug interactions have to be considered when substrates and modulators of these transporters are co-administered.…”
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1929
Role of Vitamin D in Childhood Epilepsy
Published 2022-07-01“…The aim of this review: is to evaluate the roleof vitamin D in childhood epilepsy and to study the vitamin D –antiepleptic drugs interactions among epileptic children. Conclusion: vitamin D insufficiency and deficiency are highly prevalent among children with epilepsy.A lot of antiepileptic drugs lower vitamin D level and lead to more seizures specially enzyme inducers' drugs.…”
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1930
Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections
Published 2020-08-01“…PNs offer opportunities for preventing unwanted drug interactions and degradation before reaching the target cell of tissue and thus decreasing the development of resistance in microorganisms. …”
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1931
Technology for the treatment promotion of adults living with HIV: Positive o Cuidado (Positive the Care)
Published 2023-11-01“…Results: it was developed the responsive website Positive Care (Positive o Cuidado), composed of an initial presentation screen and 13 other screens named: Family Health and You; Undetectable = Untransmissible; Antiretroviral Drugs; Routine Tests; Vaccination; Antiretroviral Delivery; Drug Interactions; Combined Prevention; Support Services; Healthy Life; Family and Reproductive Planning; Covid 19; and Questions, Curiosities, and Myths. …”
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1932
Visual symptoms with Sofosbuvir in hepatitis C treatment — a case report from Pakistan
Published 2023-02-01“…It has shown high efficacy in combination with several other drugs with low toxicity, a high resistance barrier, and minimal drug interactions with other hepatitis C DAA drugs. We describe a first of its kind case from Pakistan with visual disturbances caused by Sofosbuvir. …”
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1933
Natural Health Products (NHP’s) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends...
Published 2020-11-01“…An additional area for further research is the investigation of drug–drug interactions between NHP’s and chemotherapeutics. …”
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1934
Cardiovascular implications of the COVID-19: Management of complications and drug safety concerns
Published 2022-01-01“…This review provides an overview of evidence-based data of CV complications of COVID-19, focusing on their management strategies, as well as potential cardiac adverse effects and drug interactions, due to off-label and investigational drugs used for the treatment of COVID-19.…”
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1935
Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Use for Atherogenic Dyslipidemia in Solid Organ Transplant Patients
Published 2022-06-01“…In transplant patients, these drugs are still poorly used, despite having comparable efficacy to the general population and giving fewer drug interactions with immunosuppressants. Furthermore, there is enough evidence that PCSK9 also plays a role in other pathways, such as inflammation, which is particularly dangerous for graft survival. …”
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1936
Drug-induced QT interval prolongation in cancer patients
Published 2011-12-01“…Multiple risk factors and drug–drug interactions increase this risk for dangerous arrhythmias. …”
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1937
Glycaemic Control in Patients Undergoing Percutaneous Coronary Intervention: What Is the Role for the Novel Antidiabetic Agents? <i>A Comprehensive Review of Basic Science and Clin...
Published 2022-06-01“…We summarize existing evidence on the effects of these drugs in the setting of PCI, addressing pre-clinical and clinical studies and drug-drug interactions with antiplatelet agents, thus highlighting new opportunities for optimal long-term management of these patients.…”
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1938
The Relationship between Hydrophobicity and Drug-Protein Binding in Human Serum Albumin: A Quartz Crystal Microbalance Study
Published 2022-05-01“…In this paper, the quartz crystal microbalance with dissipation monitoring (QCM-D) was used to investigate hydrophobicity and binding strength (K<sub>D</sub>) for 10 different drugs interacting with human serum albumin (HSA). Quantitative structure activity relationship (QSAR) analysis was used to determine the relationship between drug hydrophobicity (ClogP) and HSA binding strength log(1/K<sub>D</sub>). …”
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1939
Pulmonary aspergillosis: diagnosis and treatment
Published 2022-11-01“…The management of pulmonary aspergillosis is complicated by the limited number of treatment options, drug interactions, adverse events and the emergence of antifungal resistance.…”
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1940
Massive hemoptysis in pregnancy due to invasive pulmonary aspergillosis with pulmonary tuberculosis co‐infection
Published 2024-03-01“…Both mother and baby survived, remaining well at a 6‐week follow‐up, emphasizing the complexities of managing recurrent hemoptysis during pregnancy and potential drug interactions.…”
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