Providing valid evidence for decision-making: the Drug Safety and Effectiveness Network Methods and Applications Group in Indirect Comparisons (DSEN MAGIC) by Sharon E. Straus, Brian Hutton, David Moher, Shannon E. Kelly, George A. Wells, Andrea C. Tricco

Subjects: “…drug safety and effectiveness…”
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Thai Patients’ Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study by Wongtaweepkij K, Krska J, Pongpunna S, Pongwecharak J, Jarernsiripornkul N

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Drug Safety in Translational Paediatric Research: Practical Points to Consider for Paediatric Safety Profiling and Protocol Development: A Scoping Review by Beate Aurich, Evelyne Jacqz-Aigrain

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A Drug Safety Concept (I) to Avoid Polypharmacy Risks in Transplantation by Individual Pharmacotherapy Management in Therapeutic Drug Monitoring of Immunosuppressants by Ursula Wolf

“…This concept of contextualizing a TDM value to the precise patient’s condition and comedication was established at Halle University Hospital to ensure patient, graft, and drug safety.…”
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Development of a shared decision-making intervention to improve drug safety and to reduce polypharmacy in frail elderly patients living at home by E. Drewelow, M. Ritzke, A. Altiner, A. Icks, J. Montalbo, V. Kalitzkus, S. Löscher, Y. Pashutina, S. Fleischer, J. Abraham, P. Thürmann, NK. Mann, B. Wiese, S. Wilm, A. Wollny, G. Feldmeier, T. Buuck, A. Mortsiefer

“…Results: A major challenge for GPs is to conduct a productive discussion with patients and family cares on deprescribing and drug safety. A guideline for a structured family conference with a medication check and geriatric assessment was developed and proved to be feasible in the pilot study. …”
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Ondansetron-induced QT prolongation among various age groups: a systematic review and meta-analysis by Kamaldeep Singh, Arpit Jain, Ishita Panchal, Hritik Madan, Anubhav Gupta, Aakanksha Sharma, Surabhi Gupta, Anastas Kostojchin, Anmol Singh, Ishanjit Singh Sandhu, Jayesh Mittal, Loveleen Bhogal, Shiny Teja Kolli, Vishal Reddy Bejugam, Salil Chaturvedi, Akhil Bhalla, Shobhit Piplani

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Adecuación de la seguridad del metamizol y agranulocitosis by Cristina Garcia del Campo, Miguel Murcia Soler, Inocencia Martinez-Mir, Vicente Palop Larrea

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Comparative Studies of the Effects of Two Novel Sugar Drug Candidates on the CYP 1A2 and CYP 2E1 Enzymes in Different Sexed Rats Using a “Cocktail†Approach by Chang-Xiao Liu, Mei-Yu Geng, Jie Shi

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Pharmacovigilance: Empowering healthcare professionals by Mugoša Snežana S., Stanković Maja V., Turković Nemanja M., Bešović Željka M., Šahman-Zaimović Majda M., Drljević Milorad D.

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Level of Evidence Associated with FDA Safety Communications with Drug Labeling Changes: 2010-2014 by Benjamin Hixon, Joseph M. Lowrey, Lindsay N Hume, Katelynn Mayberry, Maisha Kelly Freeman

Subjects: “…Safety, Drug safety communication, level of evidence…”
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Treatment Patterns, Effectiveness, and Safety of Originator Insulin Glargine versus Insulin Glargine-yfgn within the Veterans Health Administration by Samantha Walczuk, Francesca E. Cunningham, Xinhua Zhao, Diane Dong, Peter A. Glassman, Donald R. Miller, Deborah Khachikian, Anthony Au, Cedric Salone, Kelly Bryan, Qoua Her, Sherrie L. Aspinall

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300-fold higher neuro- and immunotoxicity from low-redox transformation of carbamazepine by Tom M. Nolte

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Adverse Effects of Fluoroquinolones: A Retrospective Cohort Study in a South Indian Tertiary Healthcare Facility by Benitta Mathews, Ashley Ann Thalody, Sonal Sekhar Miraj, Vijayanarayana Kunhikatta, Mahadev Rao, Kavitha Saravu

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Pioglitazone use and the risk of bladder cancer by Hsin-Wei Kuo, Mao-Meng Tiao, Shu-Chen Ho, Chun-Yuh Yang

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Drug-associated cardiovascular risks: A retrospective evaluation of withdrawn drugs by Kumsal Kocadal, Sahan Saygi, Fehmi Burak Alkas, Semra Sardas

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The non medical use of drugs : interim report by 394153 Canada. Ministry of National Health and Welfare. Commission of Inquiry Into the Non-medical Use of Drugs

Subjects: “…Drugs -- Safety measures…”

Data-driven drug safety signal detection methods in pharmacovigilance using electronic primary care records: A population based study by Shang-Ming Zhou, Rahman Muhammad, Ronan Lyons, Sinead Brophy

“…Conclusion Data-driven analytic methods are a valuable aid to signal detection of ADEs from large electronic health records for drug safety monitoring. This study finds the methods can detect known ADE and so could potentially be used to detect unknown ADE.…”
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CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy by Immaculate M. Langmia, Katja S. Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Masimirembwa, Julia C. Stingl

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Integrated Random Negative Sampling and Uncertainty Sampling in Active Learning Improve Clinical Drug Safety Drug–Drug Interaction Information Retrieval by Weixin Xie, Limei Wang, Limei Wang, Qi Cheng, Xueying Wang, Ying Wang, Hongyuan Bi, Bo He, Weixing Feng

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Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking by Ivan Kopljar, Hua Rong Lu, Karel Van Ammel, Martin Otava, Fetene Tekle, Ard Teisman, David J. Gallacher

“…Evaluation of 587 internal NCEs and good translation to ex vivo and in vivo models for a subset of these NCEs highlight the value of the cardiac hazard scoring in facilitating the selection of compounds during early drug safety screening. : Kopljar and colleagues developed a scoring system to evaluate the potential cardiac hazard of drugs using a hiPSC-CM-based screening assay. …”
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