Nanoparticle-assisted optical tethering of endosomes reveals the cooperative function of dyneins in retrograde axonal transport by Cui, Bianxiao, Chowdary, Praveen D., Che, Daphne L., Kaplan, Luke, Chen, Ou, Pu, Kanyi, Bawendi, Moungi

“…Dynein-dependent transport of organelles from the axon terminals to the cell bodies is essential to the survival and function of neurons. …”
Get full text
Get full text

Microtubule Retrograde Motors and Their Role in Retroviral Transport by Gianfranco Pietrantoni, Rodrigo Ibarra-Karmy, Gloria Arriagada

Subjects: Get full text

Spindly is required for rapid migration of human cells by Claudia Conte, Michelle A. Baird, Michael W. Davidson, Eric R. Griffis

Subjects: “…Dynein/Dynactin…”
Get full text

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella by Hiroaki Ishikawa, Takahiro Ide, Toshiki Yagi, Xue Jiang, Masafumi Hirono, Hiroyuki Sasaki, Haruaki Yanagisawa, Kimberly A Wemmer, Didier YR Stainier, Hongmin Qin, Ritsu Kamiya, Wallace F Marshall

Subjects: Get full text

The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA by Harish Chandra Soundararajan, Simon L Bullock

“…Our data support a novel mechanism for multi-motor translocation based on the regulation of dynein processivity by discrete cargo-associated features. …”
Get full text

Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint. by Sagar P Mahale, Amit Sharma, Sivaram V S Mylavarapu

“…The multi-functional molecular motor cytoplasmic dynein performs diverse essential roles during mitosis. …”
Get full text

Effect of conditional deletion of cytoplasmic dynein heavy chain DYNC1H1 on postnatal photoreceptors. by Tiffanie M Dahl, Michelle Reed, Cecilia D Gerstner, Guoxin Ying, Wolfgang Baehr

“…Cytoplasmic dynein (dynein 1), a major retrograde motor of eukaryotic cells, is a 1.4 MDa protein complex consisting of a pair of heavy chains (DYNC1H1) and a set of heterodimeric noncatalytic accessory components termed intermediate, light intermediate and light chains. …”
Get full text

Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii. by Gervette M Penny, Susan K Dutcher

“…In humans, outer dynein arms (ODAs) and inner dynein arms (IDAs) fail to assemble motile cilia when DNAAF4 function is disrupted. …”
Get full text

Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein by Gibbons I R, Garbarino Joan E

“…The AAA domain of midasin is evolutionarily related to that of dynein, but it appears to lack a microtubule-binding site.…”
Get full text

Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons by Urko del Castillo, Michael Winding, Wen Lu, Vladimir I Gelfand

Subjects: Get full text

Adenovirus Recruits Dynein by an Evolutionary Novel Mechanism Involving Direct Binding to pH-Primed Hexon by Julian Scherer, Richard B Vallee

Subjects: Get full text

A recurrent homozygous missense mutation in CCDC103 causes asthenoteratozoospermia due to disorganized dynein arms by Muhammad Zubair, Ranjha Khan, Ao Ma, Uzma Hameed, Mazhar Khan, Tanveer Abbas, Riaz Ahmad, Jian-Teng Zhou, Wasim Shah, Ansar Hussain, Nisar Ahmed, Ihsan Khan, Khalid Khan, Yuan-Wei Zhang, Huan Zhang, Li-Min Wu, Qing-Hua Shi

Subjects: “…asthenoteratozoospermia; ccdc103; dynein arms; male infertility…”
Get full text

Cytoplasmic dynein1 intermediate-chain2 regulates cellular trafficking and physiopathological development in Magnaporthe oryzae by Lily Lin, Ibrahim Tijjani, Hengyuan Guo, Qiuli An, Jiaying Cao, Xiaomin Chen, Wende Liu, Zonghua Wang, Justice Norvienyeku

“…However, the role of dynein in the pathogenesis of Magnaporthe oryzae is unknown. …”
Get full text

A subpellicular microtubule dynein transport machinery regulates ookinete morphogenesis for mosquito transmission of Plasmodium yoelii by Bing Liu, Cong Liu, Zhenkui Li, Wenjia Liu, Huiting Cui, Jing Yuan

“…Here we screen 7 putative dynein heavy chain (DHC) proteins in the P. yoelii and identify DHC3 showing peripheral localization in ookinetes. …”
Get full text

Dynein associates with oskar mRNPs and is required for their efficient net plus-end localization in Drosophila oocytes. by Paulomi Sanghavi, Shobha Laxani, Xuan Li, Simon L Bullock, Graydon B Gonsalvez

“…Thus, a motor other than Kinesin-1 could conceivably also participate in oskar mRNA localization. Here we show that Dynein heavy chain (Dhc), the motor subunit of the minus end-directed Dynein complex, extensively co-localizes with Khc and oskar mRNA. …”
Get full text

The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly by Petra zur Lage, Zhiyan Xi, Jennifer Lennon, Iain Hunter, Wai Kit Chan, Alfonso Bolado Carrancio, Alex von Kriegsheim, Andrew P. Jarman

Subjects: Get full text

DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice by Xiang Wang, Gan Shen, Yihong Yang, Chuan Jiang, Tiechao Ruan, Xue Yang, Liangchai Zhuo, Yingteng Zhang, Yangdi Ou, Xinya Zhao, Shunhua Long, Xiangrong Tang, Tingting Lin, Ying Shen

Subjects: Get full text

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action by Jonathan B Steinman, Cristina C Santarossa, Rand M Miller, Lola S Yu, Anna S Serpinskaya, Hideki Furukawa, Sachie Morimoto, Yuta Tanaka, Mitsuyoshi Nishitani, Moriteru Asano, Ruta Zalyte, Alison E Ondrus, Alex G Johnson, Fan Ye, Maxence V Nachury, Yoshiyuki Fukase, Kazuyoshi Aso, Michael A Foley, Vladimir I Gelfand, James K Chen, Andrew P Carter, Tarun M Kapoor

“…Cytoplasmic dyneins are motor proteins in the AAA+ superfamily that transport cellular cargos toward microtubule minus-ends. …”
Get full text

Multivalency, autoinhibition, and protein disorder in the regulation of interactions of dynein intermediate chain with dynactin and the nuclear distribution protein by Kayla A Jara, Nikolaus M Loening, Patrick N Reardon, Zhen Yu, Prajna Woonnimani, Coban Brooks, Cat H Vesely, Elisar J Barbar

Subjects: “…dynein…”
Get full text

A novel role of centrin in flagellar motility: stabilizing an inner-arm dynein motor in the flagellar axoneme by Ziyin Li

Subjects: Get full text