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The role of microtubules and the dynein/dynactin motor complex of host cells in the biogenesis of the Coxiella burnetii-containing vacuole.
Published 2019-01-01“…Rab7 and its partner RILP induce the recruitment of dynein/dynactin to late endosomes regulating its retrograde transport to the perinuclear area to fuse with lysosomes. …”
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FBB18 participates in preassembly of almost all axonemal dyneins independent of R2TP complex.
Published 2022-08-01“…Assembly of dynein arms requires cytoplasmic processes which are mediated by dynein preassembly factors (DNAAFs). …”
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Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
Published 2019-01-01“…Dynein plays roles in vesicular, organelle, chromosomal and nuclear transport but so far it is unclear how dynein activity in cells is regulated. …”
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Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm
Published 2020-12-01Subjects: Get full text
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Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor.
Published 2009“…In Drosophila, minus-end-directed transport of developmentally important transcripts by the dynein motor is mediated by seemingly divergent mRNA elements. …”
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Cyclin B degradation leads to NuMA release from dynein/dynactin and from spindle poles.
Published 2004“…Inhibition of NuMA or dynein allows completion of mitosis, despite inducing spindle pole abnormalities. …”
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Characterization of a subunit of the outer dynein arm docking complex necessary for correct flagellar assembly in Leishmania donovani.
Published 2010-01-01“…The 70 kDa subunit of the outer dynein arm docking complex consists of three subunits altogether and is essential for the assembly of the outer dynein arm onto the doublet microtubule of the flagella. …”
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Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acid.
Published 2011-01-01“…This finding suggests that NDGA may not induce dynein/dynactin transport but rather interfere with cargo release. …”
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Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
Published 2018-05-01Subjects: Get full text
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The snRNA-processing complex, Integrator, is required for ciliogenesis and dynein recruitment to the nuclear envelope via distinct mechanisms
Published 2013-11-01Subjects: Get full text
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The degradation of α--synuclein is limited by dynein to drive the AALP pathway through HDAC6 upon paraquat exposure
Published 2024-09-01Subjects: Get full text
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174
Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X.
Published 2014-01-01“…Additionally, Amblyomin-X increased the expression of various chains of the molecular motor dynein in tumor cells, modulated specific ubiquitin linkage signaling and inhibited autophagy activation by modulating mTOR, LC3 and AMBRA1 with probable dynein involvement. …”
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RUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning
Published 2022-03-01“…Here, the authors identified RUFY3 as an Arl8b effector that interacts with dynein-dynactin to drive retrograde transport and perinuclear lysosome positioning.…”
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LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains
Published 2018-06-01Subjects: Get full text
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Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway.
Published 2017-12-01“…The approach was applied to the dynein light chain LC8, a ubiquitous eukaryotic hub protein that has been suggested to be involved in motor-related functions as well as promoting the dimerization of various proteins by recognizing linear motifs in its partners. …”
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The Cytoplasmic Dynein Associated Protein NDE1 Regulates Osteoclastogenesis by Modulating M-CSF and RANKL Signaling Pathways
Published 2021-12-01Subjects: Get full text
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