Development of Epipolythiodiketopiperazine syntheses and the total synthesis of diketopiperazine alkaloids by Adams, Timothy C. (Timothy Cho)

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Carbene-catalyzed dynamic kinetic resolution for asymmetric access to phthalidyl esters and benzofuranone derivatives by Majhi, Pankaj Kumar

“…In addition, enantioselective modification of hydroxyphthalides containing natural products has also been achieved utilizing this DKR process. Secondly, enantioselective synthesis of 3,3'-disubstituted benzofuran-2(3H)-one derivatives bearing vicinal quaternary stereogenic centers, enabled by N-heterocyclic carbene catalyzed dynamic kinetic resolution process, has been developed. …”
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Part I : Highly enantioselective intermolecular alpha-alkylation of aldehydes with activated alcohols. Part II : Copper-catalyzed stereo- and enantioselective systhesis of organosi... by Zhao, Kai

“…Part II focuses on the copper-catalyzed stereo- and enantioselective synthesis of organosilanes: In chapter 3, we introduced a regio- and stereoselective silylation of α,β-acetylenic carbonyl compounds with Me2PhSi–Bpin catalyzed by CuCl/NaOtBu/xantphos system via the activation of Si–B bond, affording a plethora of synthetically important β-silyl-α,β-unsaturated carbonyl compounds in good yields and excellent E/Z selectivities. …”
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Efficient and Divergent Enantioselective Syntheses of DHPVs and Anti-Inflammatory Effect on IEC-6 Cells by Hyun Su Kim, Sungkyun Chung, Moon-Young Song, Changjin Lim, Hyeyoung Shin, Joonseong Hur, Hyuk Kwon, Young-Ger Suh, Eun-Hee Kim, Dongyun Shin, Seok-Ho Kim

“…Divergent and efficient enantioselective synthesis of (<i>S</i>)- and (<i>R</i>)-DHPV was efficiently achieved by cross-metathesis and Sharpless asymmetric dihydroxylation as a key reaction for four steps in 16% and 14% overall yields, respectively. …”
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Stereoselective reactions of arene chromium tricarbonyl complexes by Goodfellow, C

“…<p>This thesis describes the application of (arene)Cr(CO)3 methodology to the Stereoselective and enantioselective synthesis of substituted arenes. Chapter one reviews the main methods of preparation and decomplexation of (arene)Cr(CO)₃ complexes and the electronic and steric influences of the Cr(CO)₃ unit on the arene.…”

Development of novel chiral N-heterocyclic carbenes and synthetic studies towards the total synthesis of gephyronic acid by Chow, Yeong Shenq

“…The emphasis of this thesis is placed on the development of novel chiral NHCs to increase the library of chiral NHCs, investigation on the application of NHCs in catalysis and manifestation of its applicability on the enantioselective synthesis of natural products. In the introductory chapter, a general discussion of the classes and synthetic methodologies of NHCs is provided, followed by a highlight of various chiral NHCs that have been reported and their applications as chiral ligands or chiral nucleophilic catalysts in asymmetric catalysis. …”
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Stereoselective and Economical Methods for Chemical Synthesis of Essential Medicines by Mear, Sarah Jane

“…Methods for diastereo- or enantioselective synthesis are highly desirable, for exploration of biological properties of different stereoisomers, or for driving efficiency during drug manufacturing. …”
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