Structure, Function and Regulation of the Hsp90 Machinery by Jing Li, Johannes Buchner

Subjects: “…while Hsp90β is constitutively expressed. [13] Hsp90 analogues also exist in other cellular compartments such as Grp94 in the endoplasmic reticulum…”
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The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors by Guosong Wang, Jiali Cao, Mengxuan Gui, Pengfei Huang, Liang Zhang, Ruoyao Qi, Ruiqi Chen, Lina Lin, Qiangyuan Han, Yanhua Lin, Tian Chen, Peiqing He, Jian Ma, Rao Fu, Junping Hong, Qian Wu, Hai Yu, Junyu Chen, Chenghao Huang, Tianying Zhang, Quan Yuan, Jun Zhang, Yixin Chen, Ningshao Xia

“…Further, we show that PRV-LAV kills cancer cells by inducing endoplasmic reticulum (ER) stress. Moreover, PRV-LAV is responsible for reprogramming the tumor microenvironment from immunologically naïve (“cold”) to inflamed (“hot”), thereby increasing immune cell infiltration and restoring CD8+ T cell function against cancer. …”
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X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity by Yifan Hong, Xiazhu Zhou, Qi Li, Jing Chen, Yuexin Wei, Chunlan Long, Lianju Shen, Xiangqin Zheng, Dinggang Li, Xia Wang, Chenjun Yu, Shengde Wu, Guanghui Wei

“…Meanwhile, oxidative stress-induced injury and pyroptosis were activated. Both endoplasmic reticulum (ER) stress and mitophagy were involved in this process. …”
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SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer by Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana García-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asís Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar

“…SUMOylation of HuR promotes major cancer hallmarks, namely proliferation and invasion, whereas the absence of HuR SUMOylation results in a senescent phenotype with dysfunctional mitochondria and endoplasmic reticulum. Mechanistically, SUMOylation induces a structural rearrangement of the RNA recognition motifs that modulates HuR binding affinity to its target RNAs, further modifying the transcriptomic profile toward hepatic tumor progression. …”
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Ribosome distribution in HeLa cells during the cell cycle. by Yuan-Jhih Tsai, Hsing-I Lee, Alan Lin

“…Furthermore, further observations have shown that ribosomes are not distributed immune-fluorescently with nuclear envelope markers including the nuclear pore complex, the integral membrane protein gp210, the inner membrane protein lamin B2, and the endoplasm reticulum membrane during cell division we propose that the mechanism associated with ribosome segregation into daughter cells could be independent of the processes of disassembly and reassembly of the nuclear envelope.…”
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Evaluation of human platelet granules by structured illumination laser fluorescence microscopy by Fred G. Pluthero, Walter H. A. Kahr

“…Abbreviation: SIM: structured illumination microscopy; WGA: wheat germ agglutinin; FGN: fibrinogen; TSP1: thrombospondin 1; ER: endoplasmic reticulum…”
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Antiviral effects of an iminosugar derivative on flavivirus infections. by Wu, S, Lee, C, Liao, C, Dwek, R, Zitzmann, N, Lin, Y

“…Endoplasmic reticulum (ER) alpha-glucosidase inhibitors, which block the trimming step of N-linked glycosylation, have been shown to eliminate the production of several ER-budding viruses. …”

Recent Development of Advanced Fluorescent Molecular Probes for Organelle-Targeted Cell Imaging by Sha Lu, Zhiqi Dai, Yunxi Cui, De-Ming Kong

“…We focus on probes that can specially target nuclei, mitochondria, endoplasmic reticulums, and lysosomes. In each section, we first briefly introduce the significance and properties of different organelles. …”
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Low, but Physiological, Concentration of GLP-1 Stimulates Insulin Secretion Independent of the cAMP-Dependent Protein Kinase Pathway by Makoto Shigeto, Masashi Katsura, Masafumi Matsuda, Seitaro Ohkuma, Kohei Kaku

“…Keywords:: glucagon-like peptide-1 (GLP-1), cAMP-dependent protein kinase pathway, insulin secretion, intracellular calcium, endoplasmic reticulum…”
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Deltamethrin-Evoked ER Stress Promotes Neuroinflammation in the Adult Mouse Hippocampus by Muhammad M. Hossain, Abigail C. Toltin, Laura M. Gamba, Maria A. Molina

“…Endoplasmic reticulum (ER) stress and neuroinflammation are involved in the pathogenesis of many neurodegenerative disorders. …”
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Robust Profiling of Cytochrome P450s (P450ome) in Notable <i>Aspergillus</i> spp. by Wadzani Palnam Dauda, Peter Abraham, Elkanah Glen, Charles Oluwaseun Adetunji, Shakira Ghazanfar, Shafaqat Ali, Majid Al-Zahrani, Mawuli Kwamla Azameti, Sheik Emmanuel Laykay Alao, Afiniki Bawa Zarafi, Maryam Peter Abraham, Hannatu Musa

“…P450s were predicted to be located in 13 subcellular components, but the endoplasm reticulum was the dominant location across the eight <i>Aspergillus</i> species. …”
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Rescue of secretion of rare-disease associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells by Tax, G, Guay, K, Pantalone, L, Ceci, M, Soldà, T, Hitchman, C, Hill, J, Vasiljevic, S, Lia, A, Modenutti, C, Straatman, K, Santino, A, Molinari, M, Zitzmann, N, Hebert, D, Roversi, P, Trerotola, M

“…Endoplasmic reticulum (ER) retention of misfolded glycoproteins is mediated by the ER-localised eukaryotic glycoprotein secretion checkpoint, UDP-glucose glycoprotein glucosyl-transferase (UGGT). …”