Showing 261 - 280 results of 5,012 for search '"epigenomics"', query time: 0.14s Refine Results
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    Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype by Berry Nicholas B, Bapat Sharmila A

    Published 2008-11-01
    “…The involvement of both-microRNA (miRNA) mediated epigenetic regulation, as well as epigenetic-induced changes in miRNA expression further highlight an additional complexity in cancer stem cell epigenomics.</p> <p>Recent advances in array-based whole-genome/epigenome analyses will continue to further unravel the genomes and epigenomes of cancer and cancer stem cells. …”
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  6. 266

    Integrative Genomic–Epigenomic Analysis of Clozapine-Treated Patients with Refractory Psychosis by Yerye Gibrán Mayén-Lobo, José Jaime Martínez-Magaña, Blanca Estela Pérez-Aldana, Alberto Ortega-Vázquez, Alma Delia Genis-Mendoza, David José Dávila-Ortiz de Montellano, Ernesto Soto-Reyes, Humberto Nicolini, Marisol López-López, Nancy Monroy-Jaramillo

    Published 2021-02-01
    “…To find predictors of CLZ-associated phenotypes (i.e., the metabolic ratio, dosage, and response), we explore the genomic and epigenomic characteristics of 44 patients with refractory psychosis who receive CLZ treatment based on the integration of polygenic risk score (PRS) analyses in simultaneous methylome profiles. …”
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    Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome by David A. Orlando, Mei Wei Chen, Victoria E. Brown, Snehakumari Solanki, Yoon J. Choi, Eric R. Olson, Christian C. Fritz, James E. Bradner, Matthew G. Guenther

    Published 2014-11-01
    “…Here, we describe a method called ChIP with reference exogenous genome (ChIP-Rx) that allows one to perform genome-wide quantitative comparisons of histone modification status across cell populations using defined quantities of a reference epigenome. ChIP-Rx enables the discovery and quantification of dynamic epigenomic profiles across mammalian cells that would otherwise remain hidden using traditional normalization methods. …”
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    Common Altered Epigenomic Domains in Cancer Cells: Characterization and Subtle Variations by Ming-Ta Hsu, Chuan-Hsiung Chang, Tze-Tze Liu, Dow-Tien Chen, Chun-Hui Chiao, Ian Yi-Feng Chang, Yi-Chien Tsai, Kate Hua

    Published 2011-04-01
    “…Taken together these results suggest that the human genome is organized in epigenomic domains that contain various different types of genes and imply that there are cis- and trans-regulators that control these domain-wide epigenetic changes and hence gene expression in the human genome. …”
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    Epigenomic mechanisms of early adversity and HPA dysfunction: Considerations for PTSD research by Patrick O McGowan

    Published 2013-09-01
    “…In so doing, I will describe work on the Glucocorticoid Receptor (GR) and other well-characterized genes within the stress response pathway and then turn to genomic studies to illustrate the use of increasingly powerful high-throughput approaches to the study of epigenomic mechanisms.…”
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    Chemical-induced epigenome resetting for regeneration program activation in human cells by Guan Wang, Yanglu Wang, Yulin Lyu, Huanjing He, Shijia Liuyang, Jinlin Wang, Shicheng Sun, Lin Cheng, Yao Fu, Jialiang Zhu, Xinxing Zhong, Zhihan Yang, Qijing Chen, Cheng Li, Jingyang Guan, Hongkui Deng

    Published 2023-06-01
    “…Altogether, chemical reprogramming resets the epigenome through reversal of the loss of natural regeneration, representing a distinct concept for cellular reprogramming and advancing the development of regenerative therapeutic strategies.…”
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    Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups by Katherine A. Giles, Cathryn M. Gould, Qian Du, Ksenia Skvortsova, Jenny Z. Song, Madhavi P. Maddugoda, Joanna Achinger-Kawecka, Clare Stirzaker, Susan J. Clark, Phillippa C. Taberlay

    Published 2019-02-01
    “…However, the influence of chromatin remodelling on shaping the functional epigenome is not well understood. Moreover, chromatin remodellers have not been extensively explored as a collective group across two-dimensional and three-dimensional epigenomic layers. …”
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