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261
Advances of Epigenetic Biomarkers and Epigenome Editing for Early Diagnosis in Breast Cancer
Published 2022-08-01Subjects: Get full text
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262
Targeting oncogenic TERT promoter variants by allele-specific epigenome editing
Published 2023-11-01Subjects: “…Allele-specific epigenome editing (ASEE)…”
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263
The Plant Genome special section: Epigenome and epitranscriptome in plant–environment interactions
Published 2023-12-01Get full text
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264
The Microbiome, Epigenome, and Diet in Adults with Obesity during Behavioral Weight Loss
Published 2023-08-01“…Obesity has been linked to the gut microbiome, epigenome, and diet, yet these factors have not been studied together during obesity treatment. …”
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265
Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype
Published 2008-11-01“…The involvement of both-microRNA (miRNA) mediated epigenetic regulation, as well as epigenetic-induced changes in miRNA expression further highlight an additional complexity in cancer stem cell epigenomics.</p> <p>Recent advances in array-based whole-genome/epigenome analyses will continue to further unravel the genomes and epigenomes of cancer and cancer stem cells. …”
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266
Integrative Genomic–Epigenomic Analysis of Clozapine-Treated Patients with Refractory Psychosis
Published 2021-02-01“…To find predictors of CLZ-associated phenotypes (i.e., the metabolic ratio, dosage, and response), we explore the genomic and epigenomic characteristics of 44 patients with refractory psychosis who receive CLZ treatment based on the integration of polygenic risk score (PRS) analyses in simultaneous methylome profiles. …”
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267
genomeSidekick: A user-friendly epigenomics data analysis tool
Published 2022-07-01Subjects: “…epigenomics…”
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268
Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
Published 2014-11-01“…Here, we describe a method called ChIP with reference exogenous genome (ChIP-Rx) that allows one to perform genome-wide quantitative comparisons of histone modification status across cell populations using defined quantities of a reference epigenome. ChIP-Rx enables the discovery and quantification of dynamic epigenomic profiles across mammalian cells that would otherwise remain hidden using traditional normalization methods. …”
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269
Common Altered Epigenomic Domains in Cancer Cells: Characterization and Subtle Variations
Published 2011-04-01“…Taken together these results suggest that the human genome is organized in epigenomic domains that contain various different types of genes and imply that there are cis- and trans-regulators that control these domain-wide epigenetic changes and hence gene expression in the human genome. …”
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270
Epigenomic mechanisms of early adversity and HPA dysfunction: Considerations for PTSD research
Published 2013-09-01“…In so doing, I will describe work on the Glucocorticoid Receptor (GR) and other well-characterized genes within the stress response pathway and then turn to genomic studies to illustrate the use of increasingly powerful high-throughput approaches to the study of epigenomic mechanisms.…”
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271
Impact of the Exposome on the Epigenome in Inflammatory Bowel Disease Patients and Animal Models
Published 2022-07-01Get full text
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272
Acute PFOA exposure promotes epigenomic alterations in mouse kidney tissues
Published 2020-01-01Get full text
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273
Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome
Published 2021-12-01Get full text
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274
Chemical-induced epigenome resetting for regeneration program activation in human cells
Published 2023-06-01“…Altogether, chemical reprogramming resets the epigenome through reversal of the loss of natural regeneration, representing a distinct concept for cellular reprogramming and advancing the development of regenerative therapeutic strategies.…”
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275
Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks.
Published 2009-08-01Get full text
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276
Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups
Published 2019-02-01“…However, the influence of chromatin remodelling on shaping the functional epigenome is not well understood. Moreover, chromatin remodellers have not been extensively explored as a collective group across two-dimensional and three-dimensional epigenomic layers. …”
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277
Epigenomic reprogramming of therapy-resistant circulating tumor cells in colon cancer
Published 2023-12-01Subjects: “…Epigenomics…”
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278
Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition
Published 2021-05-01“…In early development, the environment triggers mnemonic epigenomic programs resulting in memory and learning experiences to confer cognitive phenotypes into adulthood. …”
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279
Early-Life Iron Deficiency Anemia Programs the Hippocampal Epigenomic Landscape
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280
Paternal Inheritance of Bisphenol A Cardiotoxic Effects: The Implications of Sperm Epigenome
Published 2021-02-01Subjects: Get full text
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