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NCDE: In-Network Caching for Directory Entries to Expedite Data Access in Tiled-Chip Multiprocessors
Published 2023-01-01“…To expedite data access, a network caching technique that leverages network-on-chip (NoC) virtual channels (VCs) as an expanded memory subsystem has emerged. Previous network caching studies focused on utilizing VCs on the NoC’s local input port as a victim cache to reduce local data access latency. …”
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Immunomodulatory Activity of the Tyrosine Kinase Inhibitor Dasatinib to Elicit NK Cytotoxicity against Cancer, HIV Infection and Aging
Published 2023-03-01“…Several studies reported that dasatinib expanded memory-like natural killer (NK) cells and γδ T cells that have been related with increased control of CML after treatment withdrawal. …”
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Predicting the dynamics of antiviral cytotoxic T-cell memory in response to different stimuli: cell population structure and protective function.
Published 2001“…The modelling predicts that: (i) stable persistence of CTL memory requires the presence of either bystander or antigen-specific stimulation above a certain threshold depending on the sensitivity of memory CTL to stimulation and their life-span; (ii) a relatively low level of stimuli (approximately 10(4) fold less on a per CTL basis compared to acute infection) is needed to stabilize the expanded memory CTL population; (iii) the presence of CTL subsets in the memory pool of different activation states and lifespans ensures the robustness of memory persistence in the face of temporal variation in the low-level stimuli and; (iv) an 'optimal' population structure of the memory CTL pool, in terms of immediate protection, requires the presence of both activated cycling and effector CTL. …”
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Changing survival, memory cell compartment, and T-helper balance of lymphocytes between severe and mild asthma
Published 2008-12-01“…Mild intermittent asthma is mainly Th2 allergen-oriented reaction during exacerbations with good level of apoptosis making the inflammation as self-limiting, while in severe persistent asthma, the inflammatory reaction mediated mainly by Th1 cytokines with progressive loss of apoptosis leading to longer exacerbations, largely expanded memory cells, CD45RO<sup>+</sup>, leading to persistent baseline inflammation.…”
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Changing survival, memory cell compartment, and T-helper balance of lymphocytes between severe and mild asthma.
Published 2008“…Mild intermittent asthma is mainly Th2 allergen-oriented reaction during exacerbations with good level of apoptosis making the inflammation as self-limiting, while in severe persistent asthma, the inflammatory reaction mediated mainly by Th1 cytokines with progressive loss of apoptosis leading to longer exacerbations, largely expanded memory cells, CD45RO+, leading to persistent baseline inflammation.…”
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Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study
Published 2023-02-01“…Interestingly, effector memory T cells were dominant in all four participants’ CD8+ expanded memory T cells; CD4+ T cells were dominated by effector memory in 2/4 participants and by central memory in the remaining two participants. …”
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DAFA: Diversity-Aware Feature Aggregation for Attention-Based Video Object Detection
Published 2022-01-01“…Whereas other methods do not store sufficient feature information without expanding memory capacity, DAFA efficiently collects diverse features while avoiding redundancy using a simple Euclidean distance-based metric. …”
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Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters
Published 2018“…Remarkably, after a contemporary aP booster, cells from donors originally primed with aP were 1) associated with increased IL-4, IL-5, IL-13, IL-9 and TGF-β and decreased IFNγ and IL-17 production;2) defective in their ex vivo capacity to expand memory cells; and 3) less capable to proliferate in vitro. …”
Journal article