Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase by Yan Qiu, Yang Zhang, Yuhang Li, Jie Ren

Subjects: Get full text

Dual Inhibition of FAAH and MAGL Counteracts Migraine-like Pain and Behavior in an Animal Model of Migraine by Rosaria Greco, Chiara Demartini, Miriam Francavilla, Anna Maria Zanaboni, Cristina Tassorelli

Subjects: Get full text

Investigating the effects of a FAAH inhibitor in the laterodorsal tegmental nucleus using a new ex vivo mouse preparation by Bala Krishna Prabhala, Jiwan Chettri, Nagalakshmi Irrinki, Abhroop Garg, Rosa Jersie-Christensen, Håvard Jenssen, Biljana Mojsoska, Neeraj Soni, Kristi A. Kohlmeier

Subjects: Get full text

Effects of the Dual FAAH/MAGL Inhibitor AKU-005 on Trigeminal Hyperalgesia in Male Rats by Rosaria Greco, Chiara Demartini, Miriam Francavilla, Anna Maria Zanaboni, Sara Facchetti, Michela Palmisani, Valentina Franco, Cristina Tassorelli

Subjects: Get full text

A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice by Georgia Balsevich, Gavin N Petrie, Daniel E Heinz, Arashdeep Singh, Robert J Aukema, Avery C Hunker, Haley A Vecchiarelli, Hiulan Yau, Martin Sticht, Roger J Thompson, Francis S Lee, Larry S Zweifel, Prasanth K Chelikani, Nils C Gassen, Matthew N Hill

Subjects: Get full text

A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs) by Dale Deutsch

Subjects: Get full text

In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors by Emanuele Criscuolo, Maria Laura De Sciscio, Filomena Fezza, Mauro Maccarrone

Subjects: Get full text

Potential of Fatty Acid Amide Hydrolase (FAAH), Monoacylglycerol Lipase (MAGL), and Diacylglycerol Lipase (DAGL) Enzymes as Targets for Obesity Treatment: A Narrative Review by Justin Matheson, Xin Ming Matthew Zhou, Zoe Bourgault, Bernard Le Foll

Subjects: Get full text

Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice by Victoria S. Cavener, Victoria S. Cavener, Andrew Gaulden, Dante Pennipede, Puja Jagasia, Jashim Uddin, Lawrence J. Marnett, Sachin Patel, Sachin Patel

Subjects: “…FAAH…”
Get full text

URB937 Prevents the Development of Mechanical Allodynia in Male Rats with Trigeminal Neuralgia by Chiara Demartini, Rosaria Greco, Anna Maria Zanaboni, Miriam Francavilla, Sara Facchetti, Cristina Tassorelli

Subjects: Get full text

Pharmacological characterization of a novel, potent, selective, and orally active fatty acid amide hydrolase inhibitor, PKM‐833 [(R)‐N‐(pyridazin‐3‐yl)‐4‐(7‐(trifluoromethyl)chroma... by Toshiya Endo, Takashi Takeuchi, Shunsuke Maehara

Subjects: Get full text

Predicting the bioactive compounds of Lentinula edodes and elucidating its interaction with genes associated to obesity through network pharmacology and in-vitro cell-based assay by Jasmeet Kaur, Humaira Farooqi, Kailash Chandra, Bibhu Prasad Panda

Subjects: Get full text

The Endocannabinoid System as a Potential Therapeutic Target for Pain Modulation by Ahmet Ulugöl

Subjects: Get full text

Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration by Shenée C. Martin, Kathryn K. Joyce, Kathryn M. Harper, Samuel J. Harp, Todd J. Cohen, Sheryl S. Moy, Graham H. Diering

Subjects: Get full text

Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes by Natalia Battista, Monica Bari, Alessia Tarditi, Caterina Mariotti, Anne-Catherine Bachoud-Lévi, Chiara Zuccato, Alessandro Finazzi-Agrò, Silvia Genitrini, Marc Peschanski, Stefano Di Donato, Elena Cattaneo, Mauro Maccarrone

Subjects: Get full text

Relation of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) with obesity and insulin resistance Relación del polimorfismo C358A del enz... by D. A. de Luis, M. González Sagrado, R. Aller, O. Izaola, R Conde

Subjects: Get full text

Clinical Data on Canabinoids: Translational Research in the Treatment of Autism Spectrum Disorders by Laura D. Carreira, Francisca C. Matias, Maria G. Campos

Subjects: Get full text

Effect of MCH1, a fatty-acid amide hydrolase inhibitor, on the depressive-like behavior and gene expression of endocannabinoid and dopaminergic-signaling system in the mouse nucleu... by C. Medina-Saldivar, G.V.E. Pardo, L.F. Pacheco-Otalora

Subjects: “…FAAH inhibitor…”
Get full text

Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver by Patricia Rivera, Patricia Rivera, Antoni Pastor, Antoni Pastor, Sergio Arrabal, Juan Decara, Antonio Vargas, Laura Sánchez-Marín, Francisco J. Pavón, Antonia Serrano, Dolores Bautista, Anna Boronat, Rafael de la Torre, Rafael de la Torre, Elena Baixeras, M. Isabel Lucena, M. Isabel Lucena, Fernando R. de Fonseca, Juan Suárez, Juan Suárez

Subjects: Get full text

Assessment of the effects of CNR1, FAAH and MGLL gene variations on the synthetic cannabinoid use disorder by Altun Beril, Cok Ismet, Noyan Cemal Onur, Kadioglu Ela, Cetin Alptekin, Sengezer Tijen, Altintas Merih, Kurnaz Samet, Dilbaz Nesrin

Subjects: Get full text