Phytohormone Abscisic Acid Improves Memory Impairment and Reduces Neuroinflammation in 5xFAD Mice by Upregulation of LanC-Like Protein 2 by Seung Ho Jeon, Namkwon Kim, Yeon-Joo Ju, Min Sung Gee, Danbi Lee, Jong Kil Lee

“…ABA treatment inhibited Aβ deposition and neuroinflammation, thus resulting in improvement of memory impairment in 5xFAD mice. Interestingly, these effects were not associated with activation of peroxisome proliferator-activated receptor gamma, well known as a molecular target of ABA, but related with modulation of the LanC-like protein 2 (LANCL2), known as a receptor of ABA. …”
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Search Strategy Analysis of 5xFAD Alzheimer Mice in the Morris Water Maze Reveals Sex- and Age-Specific Spatial Navigation Deficits by Carolina Quintanilla Sánchez, Franziska W. Schmitt, Nadine Curdt, Anna Celine Westhoff, Irina Wanda Helene Bänfer, Thomas A. Bayer, Yvonne Bouter

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First Detection and Identification of FAdV-8b as the Causative Agent of an Outbreak of Inclusion Body Hepatitis in a Commercial Broiler Farm in Greece by Vasileios Tsiouris, Tilemachos Mantzios, Konstantinos Kiskinis, Jean-Luc Guérin, Guillaume Croville, Georgia D. Brellou, Emmanouela P. Apostolopoulou, Evanthia J. Petridou, Ioanna Georgopoulou

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Curcugreen Treatment Prevented Splenomegaly and Other Peripheral Organ Abnormalities in 3xTg and 5xFAD Mouse Models of Alzheimer’s Disease by Jayeeta Manna, Gary L. Dunbar, Panchanan Maiti

“…Eighteen- and 24-month-old male and female 3xTg and 5xFAD mice were treated with CGR (100 mg/kg) for 2 months, orally. …”
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Overexpression of the Purple Perilla (<i>Perilla frutescens</i> (L.)) <i>FAD3a</i> Gene Enhances Salt Tolerance in Soybean by Zhan Li, Ying Wang, Lili Yu, Yongzhe Gu, Lijuan Zhang, Jun Wang, Lijuan Qiu

Subjects: “…<i>PfFAD3a</i>…”
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Identification of FadT as a Novel Quorum Quenching Enzyme for the Degradation of Diffusible Signal Factor in <i>Cupriavidus pinatubonensis</i> Strain HN-2 by Xudan Xu, Tian Ye, Wenping Zhang, Tian Zhou, Xiaofan Zhou, Weijun Dai, Shaohua Chen

“…We discovered that the <i>fadT</i> gene encodes acyl-CoA dehydrogenase as a novel QQ enzyme. …”
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Down-Regulation of <i>FAD2-1</i> Gene Expression Alters Lysophospholipid Composition in the Endosperm of Rice Grain and Influences Starch Properties by Jixun Luo, Lei Liu, Christine Konik-Rose, Lijun Tian, Surinder Singh, Crispin A. Howitt, Zhongyi Li, Qing Liu

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Genome-Wide Identification and Expression Analysis of Fatty Acid Desaturase (<i>FAD</i>) Genes in <i>Camelina sativa</i> (L.) Crantz by Daqian Sun, Weizhu Quan, Di Wang, Jingyan Cui, Tianyi Wang, Mei Lin, Yijin Wang, Nan Wang, Yuanyuan Dong, Xiaowei Li, Weican Liu, Fawei Wang

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(-)-Oleocanthal Nutraceuticals for Alzheimer’s Disease Amyloid Pathology: Novel Oral Formulations, Therapeutic, and Molecular Insights in 5xFAD Transgenic Mice Model by Afsana Tajmim, Areli K. Cuevas-Ocampo, Abu Bakar Siddique, Mohammed H. Qusa, Judy Ann King, Khaldoun S. Abdelwahed, Jafrin Jobayer Sonju, Khalid A. El Sayed

“…OC-PF and OC-SD improved memory deficits of 5xFAD mice in behavioral studies. OC-PF and OC-SD exhibited significant attenuation of the accumulation of Aβ plaques and tau phosphorylation in the brain of 5xFAD female mice. …”
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Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse by Simone M. Crivelli, Zainuddin Quadri, Hemendra J. Vekaria, Zhihui Zhu, Priyanka Tripathi, Ahmed Elsherbini, Liping Zhang, Patrick G. Sullivan, Erhard Bieberich

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Oral Administration of Probiotic Bacteria Alleviates Tau Phosphorylation, Aβ Accumulation, Microglia Activation, and Memory Loss in 5xFAD Mice by Yeong Jin Kim, Bo-Ram Mun, Kyu Yeong Choi, Won-Seok Choi

“…The aim of our study was to elucidate the impact of probiotics on the pathological features of AD in a 5xFAD model. Probiotics (<i>Bifidobacterium lactis</i>, <i>Levilactobacillus brevis</i>, and <i>Limosilactobacillus fermentum</i>) were orally administered in 5xFAD mice to modify the GM composition. …”
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Structural Insight into the Working Mechanism of the FAD Synthetase from the Human Pathogen <i>Streptococcus pneumoniae</i>: A Molecular Docking Simulation Study by Sunghark Kwon

“…Flavin adenine dinucleotide synthetases (FADSs) catalyze FAD biosynthesis through two consecutive catalytic reactions, riboflavin (RF) phosphorylation and flavin mononucleotide (FMN) adenylylation. …”
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DHCR24 reverses Alzheimer’s disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xFAD mice by Wen-bin Zhang, Yue Huang, Xiao-rou Guo, Meng-qi Zhang, Xiang-shan Yuan, Heng-bing Zu

“…Surprisingly, the cognitive impairment of 5xFAD mice was significantly reversed after DHCR24-based gene therapy. …”
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Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered by Alex B. Speers, Alex B. Speers, Kirsten M. Wright, Kirsten M. Wright, Mikah S. Brandes, Mikah S. Brandes, Nareg Kedjejian, Nareg Kedjejian, Donald G. Matthews, Maya Caruso, Christopher J. Harris, Seiji Koike, Seiji Koike, Thuan Nguyen, Thuan Nguyen, Joseph F. Quinn, Joseph F. Quinn, Joseph F. Quinn, Amala Soumyanath, Amala Soumyanath, Nora E. Gray, Nora E. Gray

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Correction: Detection of β-amyloid aggregates/plaques in 5xFAD mice by labelled native PLGA nanoparticles: implication in the diagnosis of Alzheimer’s disease by Karthivashan Govindarajan, Satyabrata Kar

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Status Gizi, Harga Diri, dan Citra Tubuh dalam Perilaku Fad Diets pada Remaja Putri SMA Negeri 6 Yogyakarta by RESPATI, SUNDARI HANA, Kandarina, BJ Istiti

“…There is no relationship between self-esteem and fad diets behavior (p-value=0,997). Conclusion: There is a relationship between nutritional status and body image with fad diets behavior but there is no relationship between self-esteem and fad diets behavior.…”

Molecular characterization of Malaysian fowl adenovirus (FAdV) serotype 8b species E and pathogenicity of the virus in specific pathogen-free chicken by Sabarudin, Nur Syazana, Tan, Sheau Wei, Phang, Yuen Fun, Omar, Abdul Rahman

“…All 12 serotypes of fowl adenovirus (FAdV) can cause IBH. Objectives: To characterize FAdV isolates based on phylogenetic analysis, and to study the pathogenicity of FAdV-8b in specific-pathogen-free (SPF) chickens following virus inoculation via oral and intramuscular (IM) routes. …”

Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight? by Manja M. Zec, Irena Krga, Ljiljana Stojković, Maja Živković, Biljana Pokimica, Aleksandra Stanković, Maria Glibetic

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Correction: Shokeen, B., et al. Role of FAD-I in Fusobacterial Interspecies Interaction and Biofilm Formation. <i>Microorganisms</i> 2020, 8, 70 by Bhumika Shokeen, Jane Park, Emily Duong, Sonam Rambhia, Manash Paul, Aaron Weinberg, Wenyuan Shi, Renate Lux

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CRISPR/Cas9-mediated editing of double loci of BnFAD2 increased the seed oleic acid content of rapeseed (Brassica napus L.) by Han Liu, Han Liu, Baogang Lin, Yun Ren, Pengfei Hao, Lan Huang, Bowen Xue, Lixi Jiang, Yang Zhu, Shuijin Hua

“…Many methods exist to increase seed oleic acid content, such as the CRISPR/Cas9-mediated genome editing system, yet there is no report on seed oleic acid content improvement via this system’s precise editing of the double loci of BnFAD2. Here, a precise CRISPR/Cas9-mediated genome editing of the encoded double loci (A5 and C5) of BnFAD2 was established. …”
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