Second Wave, Late-Stage Neuroinflammation in Cleared Brains of Aged 5xFAD Alzheimer’s Mice Detected by Macrolaser Light Sheet Microscopy Imaging by Suk Hyun Lee, Hye Joo Son

Subjects: Get full text

I2-Imidazoline Ligand CR4056 Improves Memory, Increases ApoE Expression and Reduces BBB Leakage in 5xFAD Mice by Bibiana C. Mota, Nathan Ashburner, Laura Abelleira-Hervas, Liyueyue Liu, Robertas Aleksynas, Lucio Claudio Rovati, Gianfranco Caselli, Magdalena Sastre

“…In this study, our aim was to determine the therapeutic potential of the powerful analgesic I2-imidazoline ligand CR4056 in the 5xFAD model of AD, since this ligand has been proven to be safely tolerated in humans. …”
Get full text

Long-Term Treatment of Cuban Policosanol Attenuates Abnormal Oxidative Stress and Inflammatory Response via Amyloid Plaques Reduction in 5xFAD Mice by Jin-Ho Kim, Dong-Kyun Lim, Yoo-Hun Suh, Keun-A Chang

Subjects: Get full text

Comprehensive analysis of dysregulated circular RNAs and construction of a ceRNA network involved in the pathology of Alzheimer’s disease in a 5 × FAD mouse model by Ting Sun, Li Zeng, Zhongdi Cai, Qingshan Liu, Zhuorong Li, Rui Liu

Subjects: Get full text

New Positive TRPC6 Modulator Penetrates Blood–Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice by Nikita Zernov, Alexander V. Veselovsky, Vladimir V. Poroikov, Daria Melentieva, Anastasia Bolshakova, Elena Popugaeva

“…We demonstrate that it binds to the extracellular agonist binding site of the human TRPC6, protects hippocampal mushroom spines from amyloid toxicity in vitro, efficiently recovers synaptic plasticity in 5xFAD brain slices, penetrates the blood–brain barrier and recovers cognitive deficits in 5xFAD mice. …”
Get full text

First detection of FAdV serotype 8b associated with Inclusion Body Hepatitis in broiler flocks in the southern part of Iraq during, 2022-2023 by Qayssar Ali Kraidi, Waleed Majeed Almayahi, Harith Abdulla Najem

“… Field observations reported many outbreaks of IBH infection in poultry flocks in different regions of Basra province leading to high economic losses, and the diagnosis of the disease is based on clinical signs and gross pathological lesions. Little information on FAdV recently circulating in the southern part of Iraq; thus, partial sequencing of hexon gene of four FAdV has been detected in the present study during the period between mid-2022 to the beginning of 2023 from various FAdV outbreaks in commercial broiler farms in southern parts of Iraq. …”
Get full text

Expression of <i>SCD</i> and <i>FADS2</i> Is Lower in the Necrotic Core and Growing Tumor Area than in the Peritumoral Area of Glioblastoma Multiforme by Jan Korbecki, Klaudyna Kojder, Dariusz Jeżewski, Donata Simińska, Maciej Tarnowski, Patrycja Kopytko, Krzysztof Safranow, Izabela Gutowska, Marta Goschorska, Agnieszka Kolasa-Wołosiuk, Barbara Wiszniewska, Dariusz Chlubek, Irena Baranowska-Bosiacka

“…We found no differences in the expression of <i>SCD</i>, fatty acid desaturases 1 (<i>FADS1),</i> or <i>FADS2</i> between the sexes. Necrotic conditions and nutritional deficiency increased the expression of the studied desaturase in human brain (glioblastoma astrocytoma) U-87 MG cells. …”
Get full text

Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis by Xiao Cheng, Li Chi, Tianqiong Lin, Fengyin Liang, Zhong Pei, Jianbo Sun, Wei Teng

“…The cells of peripheral blood, spleen and bone marrow from 5xFAD mice were treated with Pg to detect the proportional and functional alterations of mMDSCs in vitro. …”
Get full text

Design and Identification of a Novel Antiviral Affinity Peptide against Fowl Adenovirus Serotype 4 (FAdV-4) by Targeting Fiber2 Protein by Xiao Chen, Qiang Wei, Fusheng Si, Fangyu Wang, Qingxia Lu, Zhenhua Guo, Yongxiao Chai, Rongfang Zhu, Guangxu Xing, Qianyue Jin, Gaiping Zhang

Subjects: “…fowl adenovirus 4 (FAdV-4)…”
Get full text

Depresi, Paparan Media, dan Pengaruh Teman Sebaya dalam Perilaku Fad Diets Pada Remaja Putri di SMA Negeri 6 Yogyakarta by CHAERANI, HURIN RAFIQA, Kandarina, BJ Istiti

“…Therefore, in recent years, many adolescent girls performed fad diets as efforts of weight-loss so they can be accepted by both the social life and the society. …”

Ekono'Cinta’Metrik: bila cinta menyatukan kita (Econo'Love'Metrics: when love unites us) / Fadli Fizari Abu Hassan Asari by Abu Hassan Asari, Fadli Fizari

Get full text

Kontekstualisasi Maqashid Shari’ah Dalam Sustainable Development Goals by Mohammad Farid Fad

Get full text

STUDY ON CRITICAL CTOD OF BIG-THICKNESS AND HIGH-STRENGTH STEELS by XIA ZiYu, MIAO ZhangMu, MA Tao, CHEN Gang, PENG Sheng

Subjects: “…BS7910;FAD;EQ70;Microstructure;Critical CTOD…”
Get full text

Flavin Adenine Dinucleotide Fluorescence as an Early Marker of Mitochondrial Impairment During Brain Hypoxia by Nikolaus Berndt, Richard Kovács, Jörg Rösner, Iwona Wallach, Jens P. Dreier, Agustin Liotta

Subjects: “…FAD…”
Get full text

Fowl adenovirus serotype 4 enters leghorn male hepatocellular cells via the clathrin-mediated endocytosis pathway by Ting Wang, Lizhen Wang, Wei Li, Xiaolan Hou, Wenchi Chang, Bo Wen, Shuizhong Han, Yan Chen, Xuefeng Qi, Jingyu Wang

Subjects: “…FAdV-4…”
Get full text

Low-Denaturazing Glucose Oxidase Immobilization onto Graphite Electrodes by Incubation in Chitosan Solutions by Mireia Buaki-Sogó, Laura García-Carmona, Mayte Gil-Agustí, Marta García-Pellicer, Alfredo Quijano-López

Subjects: Get full text

Exploiting the Fruitfly, <i>Drosophila melanogaster</i>, to Identify the Molecular Basis of Cryptochrome-Dependent Magnetosensitivity by Adam Bradlaugh, Anna L. Munro, Alex R. Jones, Richard A. Baines

Subjects: “…FAD…”
Get full text

Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults by Vladimir Adrien, Vladimir Adrien, Justine Liewig, Thomas Diot, Florian Ferreri, Florian Ferreri, Stephane Mouchabac, Stephane Mouchabac, Caroline Dubertret, Julie Bourgin

Subjects: Get full text

Vitamin B2 enables regulation of fasting glucose availability by Peter M Masschelin, Pradip Saha, Scott A Ochsner, Aaron R Cox, Kang Ho Kim, Jessica B Felix, Robert Sharp, Xin Li, Lin Tan, Jun Hyoung Park, Liping Wang, Vasanta Putluri, Philip L Lorenzi, Alli M Nuotio-Antar, Zheng Sun, Benny Abraham Kaipparettu, Nagireddy Putluri, David D Moore, Scott A Summers, Neil J McKenna, Sean M Hartig

Subjects: Get full text

A near complete genome assembly of chia assists in identification of key fatty acid desaturases in developing seeds by Leiting Li, Jingjing Song, Meiling Zhang, Shahid Iqbal, Yuanyuan Li, Heng Zhang, Hui Zhang

Subjects: Get full text