Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif by Wuyang Shi, Shibo Sun, Haowen Liu, Yao Meng, Kangshuai Ren, Guoying Wang, Minghui Liu, Jiaqi Wu, Yue Zhang, Huang Huang, Meiyun Shi, Weiping Xu, Qiang Ma, Bingbing Sun, Jianqiang Xu

“…In this study, utilizing single amino acid substitution and Excitation-Emission Matrix (EEM) fluorescence spectrum analysis, we discovered that the guiding bar communicates with the FAD and modulates the electron flow of the enzyme. …”
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A vitamin-B2-sensing mechanism that regulates gut protease activity to impact animal’s food behavior and growth by Bin Qi, Marina Kniazeva, Min Han

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The crystal structure of human ferroptosis suppressive protein 1 in complex with flavin adenine dinucleotide and nicotinamide adenine nucleotide by Shijian Feng, Xiaofang Huang, Dan Tang, Xiaoyu Liu, Liang Ouyang, Dehua Yang, Kunjie Wang, Banghua Liao, Shiqian Qi

Subjects: “…6‐OH‐FAD…”
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How Aqueous Solvation Impacts the Frequencies and Intensities of Infrared Absorption Bands in Flavin: The Quest for a Suitable Solvent Model by D. P. Ngan Le, Gary Hastings, Samer Gozem

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Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping by Anaïs Depaix, Anaïs Depaix, Ewa Grudzien-Nogalska, Bartlomiej Fedorczyk, Megerditch Kiledjian, Jacek Jemielity, Joanna Kowalska

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Flavin adenine dinucleotide functionalized gold nanoparticles for the electrochemical detection of dopamine by Jennifer de Pontes Medrades, Cristiane C. Maciel, Ariana de Souza Moraes, Fábio de Lima Leite, Marystela Ferreira

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First Record of Cetacean Killed in an Artisanal Fish Aggregating Device in the Mediterranean Sea by Valerio Manfrini, Caterina Maria Fortuna, Cristiano Cocumelli

Subjects: “…fish aggregating device (FAD)…”
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Parameters for Irreversible Inactivation of Monoamine Oxidase by Rona R. Ramsay, Livia Basile, Antonin Maniquet, Stefanie Hagenow, Matteo Pappalardo, Maria Chiara Saija, Sharon D. Bryant, Alen Albreht, Salvatore Guccione

Subjects: “…FAD…”
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The effect of Abi3 locus deletion on the progression of Alzheimer’s disease-related pathologies by Hande Karahan, Hande Karahan, Daniel C. Smith, Daniel C. Smith, Byungwook Kim, Byungwook Kim, Brianne McCord, Brianne McCord, Jordan Mantor, Jordan Mantor, Sutha K. John, Sutha K. John, Md Mamun Al-Amin, Md Mamun Al-Amin, Luke C. Dabin, Luke C. Dabin, Jungsu Kim, Jungsu Kim, Jungsu Kim

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FLIM of NAD(P)H in Lymphatic Nodes Resolves T-Cell Immune Response to the Tumor by Anna V. Izosimova, Marina V. Shirmanova, Vladislav I. Shcheslavskiy, Daria A. Sachkova, Artem M. Mozherov, George V. Sharonov, Elena V. Zagaynova, Diana V. Yuzhakova

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Fusobacterium nucleatum and its associated systemic diseases: epidemiologic studies and possible mechanisms by Zixin Fan, Pengzhou Tang, Cheng Li, Qi Yang, Yan Xu, Chuan Su, Lu Li

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Research Note: Overview of fowl adenovirus serotype 4: structure, pathogenicity, and progress in vaccine development by Iman Pouladi, Hamideh Najafi, Amin Jaydari

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Sebaran Jenis Ikan Pelagis yang Ditangkap Menggunakan Pancing Ulur pada Rumpon di Laut Pemangkat Kabupaten Sambas by Heriyansah Heriyansah, Saifullah Saifullah

Subjects: “…pelagic fish, composition, Pemangkat sea, handlines, FADs.…”
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Whole-Genome Sequencing Analysis of Quorum Quenching Bacterial Strain <i>Acinetobacter lactucae</i> QL-1 Identifies the FadY Enzyme for Degradation of the Diffusible Signal Factor by Tian Ye, Tian Zhou, Xudan Xu, Wenping Zhang, Xinghui Fan, Sandhya Mishra, Lianhui Zhang, Xiaofan Zhou, Shaohua Chen

“…The determination of FadY activity in vitro revealed that the fatty acyl-CoA synthetase FadY had remarkable catalytic activity. …”
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RETRACTED ARTICLE: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis by Panchanan Maiti, Zackary Bowers, Ali Bourcier-Schultz, Jarod Morse, Gary L. Dunbar

“…In the present study, we have investigated whether SLCP has any preservative role on affected dendritic spines and synaptic markers in 5xFAD mice. Methods Six- and 12-month-old 5xFAD and age-matched wild-type mice received oral administration of SLCP (100 mg/kg body weight) or equivalent amounts of vehicle for 2 months. …”
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Comparative Analysis and Structural Modeling of <i>Elaeis oleifera</i> FAD2, a Fatty Acid Desaturase Involved in Unsaturated Fatty Acid Composition of American Oil Palm by Rayda Ben Ayed, Tejas Chirmade, Mohsen Hanana, Khalil Khamassi, Sezai Ercisli, Ravish Choudhary, Narendra Kadoo, Rohini Karunakaran

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Maternal DHA-rich n-3 PUFAs supplementation interacts with FADS genotypes to influence the profiles of PUFAs in the colostrum among Chinese Han population: a birth cohort study by Ping Li, Yuhui Chen, Jieyun Song, Lailai Yan, Tiantian Tang, Rui Wang, Xiuqin Fan, Yurong Zhao, Kemin Qi

“…Meanwhile, their venous blood samples were obtained for DNA extraction to detect the genotypes of SNPs in the Fads1, Fads2, Fads3, Elovl2 and Elovl5 using the Matrix-Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry. …”
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Retraction Note: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis by Panchanan Maiti, Zackary Bowers, Ali Bourcier-Schultz, Jarod Morse, Gary L. Dunbar

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Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice by Sahithi Attaluri, Jenny Jaimes Gonzalez, Maha Kirmani, Andrew D. Vogel, Raghavendra Upadhya, Maheedhar Kodali, Leelavathi N. Madhu, Shama Rao, Bing Shuai, Roshni S. Babu, Charles Huard, Ashok K. Shetty

“…We administered a single dose of 25 × 109 hiPSC-NSC-EVs labeled with PKH26, and different cohorts of naïve and 5xFAD mice receiving EVs were euthanized at 45 min or 6 h post-administration.ResultsAt 45 min post-administration, EVs were found in virtually all subregions of the forebrain, midbrain, and hindbrain of naïve and 5xFAD mice, with predominant targeting and internalization into neurons, interneurons, and microglia, including plaque-associated microglia in 5xFAD mice. …”
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Docosahexaenoic Acid and Eicosapentaenoic Acid Intakes Modulate the Association of <i>FADS2</i> Gene Polymorphism rs526126 with Plasma Free Docosahexaenoic Acid Levels in Overweight Children by Alexandra Mihailescu, Vlad Serafim, Corina Paul, Nicoleta Andreescu, Diana-Andreea Tiugan, Paul Tutac, Iulian Velea, Cristian G. Zimbru, Costela Lacrimioara Serban, Adina Iuliana Ion, Vlad Laurentiu David, Alin Ionescu, Maria Puiu, Mihai Dinu Niculescu

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