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Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats
Published 2024-01-01“…Specifically, low dose FAD facilitated extinction of cocaine CPP, whereas high dose FAD impaired it. …”
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563
Immunogenicity of Novel Live Vaccine Based on an Artificial rHN20 Strain against Emerging Fowl Adenovirus 4
Published 2021-10-01“…In recent years, hepatitis-hydropericardium syndrome (HHS), caused by novel fowl adenovirus 4 (FAdV-4), has caused serious economic losses to the poultry industry. …”
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564
KOMPOSISI JENIS DAN UKURAN IKAN YANG DITANGKAP PADA RUMPON DENGAN PANCING ULUR DI SELAT MAKASSAR
Published 2018-11-01“…The size spread of skipjack tuna (23-42 cm and 29-53 cm), Bullet Tuna (16.5-25.0 cm and 18.5-28.5 cm), Yellowfin Tuna (25-120 cm and 80-160 cm) and Indian mackerel (16-25 cm and 16-25 cm) for shallow and deep FAD respectively. The fish size distribution caught at shallow and deep FAD was skipjack tuna, whereas the Auxis rochei rochei and Thunnus albacares had bigger size distribution in deep sea FAD, while the Rastrelliger kanagurta had relatively similar size distribution in shallow or deep sea FAD. …”
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565
A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
Published 2023-12-01“…In vivo, male and female, E3FAD (5xFAD+/−/APOE3 +/+) and E4FAD (5xFAD+/−/APOE4 +/+) mice were treated with CS via intraperitoneal injection at early (from 4 to 8 months of age) and late ages (from 8 to 10 months of age). …”
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566
Loosening ER–Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain
Published 2021-08-01“…Presenilin 2 (PS2), one of the three proteins in which mutations are linked to familial Alzheimer’s disease (FAD), exerts different functions within the cell independently of being part of the γ-secretase complex, thus unrelated to toxic amyloid peptide formation. …”
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567
Oxidative Quality of Acid Oils and Fatty Acid Distillates Used in Animal Feeding
Published 2021-08-01“…Acid oils (AO) and fatty acid distillates (FAD) are byproducts from chemical and physical refining of edible oils and fats, respectively. …”
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Computational insights on the hydride and proton transfer mechanisms of L-proline dehydrogenase.
Published 2023-01-01“…Subsequently, a hydride ion transfers from L-proline to FAD with a higher activation barrier. The enzyme-product complex showed a strong interaction between reduced FAD and iminoproline, which might help to explain why a step in the oxidative half-reaction is rate-limiting.…”
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572
Dynamic control of electron transfers in diflavin reductases.
Published 2012“…The catalytic domains are analogous to existing globular proteins: the FMN domain is analogous to flavodoxins while the FAD domain resembles ferredoxin reductases. The first structural determination of one member of the diflavin reductases family raised some questions about the architecture of the enzyme during catalysis: both FMN and FAD were in perfect position for interflavin transfers but the steric hindrance of the FAD domain rapidly prompted more complex hypotheses on the possible mechanisms for the electron transfer from FMN to external acceptors. …”
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573
Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer’s Disease
Published 2020-09-01“…HFD feeding impaired energy metabolism in male 5xFAD mice, leading to increased locomotor activity, energy expenditure, and food intake. 5xFAD mice on HFD had elevated circulating lipids and worsened glucose intolerance. …”
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574
An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes
Published 2013“…Here, we show that StaC and InkE, which mediate a net 4-electron oxidation, bind FAD with a micromolar Kd, whereas RebC and AtmC, which mediate a net 8-electron oxidation, bind FAD with a nanomolar Kd while displaying the same FAD redox properties. …”
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575
Pathogenicity and immunogenicity of attenuated fowl adenovirus from chicken embryo liver cells in commercial broiler chickens
Published 2021“…Fowl adenovirus (FAdV) infection is a major viral threat to poultry industry worldwide. …”
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576
Surrogate end points: studying their benefits, taxonomy, and semantics.
Published 2012Journal article -
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