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    Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease. by Sevda T Boyanova, Ethlyn Lloyd-Morris, Christopher Corpe, Khondaker Miraz Rahman, Doaa B Farag, Lee K Page, Hao Wang, Alice L Fleckney, Ariana Gatt, Claire Troakes, Gema Vizcay-Barrena, Roland Fleck, Suzanne J Reeves, Sarah A Thomas

    Published 2023-01-01
    “…Brain distribution of [3H]amisulpride was determined using in situ perfusion in wild type (WT) and 5xFamilial AD (5xFAD) mice. With transmission electron microscopy (TEM) we investigated brain capillary degeneration in WT mice, 5xFAD mice and human samples. …”
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  17. 937

    Hnf4α Is Involved in LC-PUFA Biosynthesis by Up-Regulating Gene Transcription of Elongase in Marine Teleost Siganus canaliculatus by Yuanyou Li, Xiaowei Zeng, Yewei Dong, Cuiying Chen, Cuihong You, Guoxia Tang, Junliang Chen, Shuqi Wang

    Published 2018-10-01
    “…The rabbitfish Siganus canaliculatus is the first marine teleost shown to be able to biosynthesize long-chain polyunsaturated fatty acids (LC-PUFA) from C18 PUFA precursors catalyzed by two fatty acyl desaturases (fad) including Δ4 Fad and Δ6/Δ5 Fad as well as two elongases (Elovl4 and Elovl5). …”
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  18. 938

    Two-Photon Excited Fluorescence of NADH-Alcohol Dehydrogenase Complex in a Mixture with Bacterial Enzymes by Ioanna A. Gorbunova, Maxim E. Sasin, Dmitry V. Yachkov, Denis A. Volkov, Alexei D. Vedyaykin, Andrey A. Nikiforov, Oleg S. Vasyutinskii

    Published 2023-01-01
    “…It was shown that enzyme-bound pyridoxal 5-phosphate fluorescence can be separated from enzyme-bound NAD(P)H and FAD through analysis of short fluorescence decay times of about tens of picoseconds. …”
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  19. 939

    Family functioning and patients’ depressive symptoms: comparison in perceived family function between patients who had an acute ischaemic stroke and their primary family caregivers... by Jing Wang, Juan Li, Bei Wu, Xiangjing Kong, Huanzhi Zhu, Jiaqi Zhong, Yanpei Cao

    Published 2023-11-01
    “…A total of 115 patients (76.9%) and 124 caregivers (73.4%) had a score of 2 or higher in FAD-general functioning (GF), indicating unhealthy family functioning. …”
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  20. 940

    Alterations in the Gut-Microbial-Inflammasome-Brain Axis in a Mouse Model of Alzheimer’s Disease by Pradeep K. Shukla, David F. Delotterie, Jianfeng Xiao, Joseph F. Pierre, RadhaKrishna Rao, Michael P. McDonald, Mohammad Moshahid Khan

    Published 2021-04-01
    “…To this end, we observe significantly altered gut microbiota compositions in young and old 5xFAD mice compared to age-matched non-transgenic mice. …”
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