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1001
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1002
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1003
Cross-system excision of chaperone-mediated proteolysis in chaperone-assisted recombinant protein production.
Published 2010Journal article -
1004
The pathogenic aβ43 is enriched in familial and sporadic Alzheimer disease.
Published 2013-01-01“…Aβ42 and Aβ43 were enriched in the less soluble fractions (SDS and FA) of SAD and FAD cases in both occipital and frontal cortex. …”
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Article -
1005
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD
Published 2023-08-01“…In the present study, we investigated whether the TKIs ibrutinib, PD180970, and cabozantinib, which have different on-targets, selectively regulate AD pathology in 3.5- to 4-month-old 5xFAD mice (a model of the early phase of AD). Ibrutinib (10 mg/kg, i.p.) effectively reduced amyloid-β (Aβ) plaque number, tau hyperphosphorylation and neuroinflammation in 5xFAD mice. …”
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Article -
1006
Molecular typing of fowl adenovirus associated with gizzard erosion in commercial layer grower chicken in Tamil Nadu
Published 2020-10-01“…Concurrent infection of chicken anaemia virus (CAV) was also screened by PCR for 419 bp VP2 gene of CAV and found that all the seven flocks which were PCR positive for FAdV also found positive for CAV. Sequencing and phylogenetic analysis of 897 bp FAdV hexon gene revealed that, it was belonged to FAdV serotypes 2 and 3 of species D.…”
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Article -
1007
Thioredoxin Reductase-Type Ferredoxin: NADP<sup>+</sup> Oxidoreductase of <i>Rhodopseudomonas palustris</i>: Potentiometric Characteristics and Reactions with Nonphysiological Oxid...
Published 2022-05-01“…It is highly possible that the FADH· to FAD oxidation reaction is the rate-limiting step during the reoxidation of reduced FAD. …”
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Article -
1008
Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production
Published 2023-02-01“…Study of the mutations that activate and restore the cleavage of FAD mutants is necessary to understand the mechanism of Aβ production. …”
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1009
Genomic Epidemiology and Evolution of Fowl Adenovirus 1
Published 2023-09-01“…Fowl adenovirus 1 (FAdV-1) is the main cause of gizzard erosion in chickens. …”
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1010
Salinomycin biosynthesis reversely regulates the β‐oxidation pathway in Streptomyces albus by carrying a 3‐hydroxyacyl‐CoA dehydrogenase gene in its biosynthetic gene cluster...
Published 2022-12-01“…Deletion of fadB3 significantly reduced the production of salinomycin. …”
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Article -
1011
Visual short-term memory binding deficit in familial Alzheimer's disease
Published 2016“…Twenty individuals with pathological mutations in presenilin 1 or amyloid precursor protein genes for familial Alzheimer's disease (FAD) were tested together with 62 healthy controls. …”
Journal article -
1012
Redox properties of flavocytochrome c3 from Shewanella frigidimarina NCIMB400.
Published 1999“…The FAD behaves as a cooperative two-electron center with a pH-dependent reduction potential that is modulated (pKox at 6.5) by ionization of a nearby residue. …”
Journal article -
1013
The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR
Published 2012“…The crystal structures of mammalian and yeast CPRs show a compact organization for the two domains containing FMN (flavin mononucleotide) and FAD (flavin adenine dinucleotide), with a short interflavin distance consistent with fast ET from the NADPH-reduced FAD to the second flavin FMN. …”
Journal article -
1014
Comparative sequence analysis, pathogenicity and immunogenicity of attenuated fowl adenovirus isolates as experimental vaccines against inclusion body hepatitis of commercial broil...
Published 2021“…Introduction: Fowl adenoviruses (FAdV) cause inclusion body hepatitis (IBH) in chickens and new vaccination strategies against IBH are needed as an effective control measure in the poultry industry. …”
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1015
Pathogenicity and propagation of UPMT27 field isolate of Malaysia fowl adenovirus in chicken embryo liver cells
Published 2018“…The present study was carried out to propagate a field isolate of FAdV (UPM T27) and examine its pathogenicity in chicken egg embryo and chicken embryo liver cells. …”
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Conference or Workshop Item -
1016
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1017
Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease
Published 2023-02-01“…We found that the gal3-induced disruption was mediated by the gal3 carbohydrate-recognition domain and prevented by the gal3 inhibitor TD139, which also prevented Aβ42-induced degradation of gamma oscillations. Furthermore, the 5×FAD mice lacking gal3 (5×FAD-Gal3KO) exhibited WT-like gamma network dynamics and decreased Aβ plaque load. …”
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Article -
1018
Thwarted belongingness, perceived burdensomeness, and acquired capability for suicide among university students of Bangladesh: Scales validation and status assessment
Published 2022-10-01“…Confirmatory factor analysis revealed a two-factor structure of Bangla INQ after dropping three items from thwarted belongingness domain (item 9, 11, and 12) and a single factor structure for Bangla ACSS-FAD after dropping three items (item 1, 4, and 6). …”
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1019
A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021)
Published 2021-10-01“…A surge in fowl adenovirus (FAdV) causing inclusion body hepatitis (IBH) outbreaks has occurred in several countries in the last two decades. …”
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1020
BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides
Published 2023-05-01“…Similar scRNA-seq was also conducted using AD mice with conditional deletion of Bace1 in the adult stage (5xFAD;Bace1 fl/fl ;UBC-creER compared to 5xFAD;Bace1 fl/fl controls). …”
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Article