A gap for me: Entrepreneurs and entry. by Nocke, V

NRG: A network perspective on applications' performance by Zilberman, N, Moore, AW, Cooper, B, Woodruff, J, Tokusashi, Y, Bressana, P, Ramanujam, M, Popescu, DA, Galea, S

Cross-system excision of chaperone-mediated proteolysis in chaperone-assisted recombinant protein production. by Martínez-Alonso, M, Villaverde, A, Ferrer-Miralles, N

The pathogenic aβ43 is enriched in familial and sporadic Alzheimer disease. by Anna Sandebring, Hedvig Welander, Bengt Winblad, Caroline Graff, Lars O Tjernberg

“…Aβ42 and Aβ43 were enriched in the less soluble fractions (SDS and FA) of SAD and FAD cases in both occipital and frontal cortex. …”
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Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD by Hyun-ju Lee, Jeong-Woo Hwang, Jin-Hee Park, Yoo Joo Jeong, Ji-Yeong Jang, Hyang-Sook Hoe

“…In the present study, we investigated whether the TKIs ibrutinib, PD180970, and cabozantinib, which have different on-targets, selectively regulate AD pathology in 3.5- to 4-month-old 5xFAD mice (a model of the early phase of AD). Ibrutinib (10 mg/kg, i.p.) effectively reduced amyloid-β (Aβ) plaque number, tau hyperphosphorylation and neuroinflammation in 5xFAD mice. …”
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Molecular typing of fowl adenovirus associated with gizzard erosion in commercial layer grower chicken in Tamil Nadu by S CHITRADEVI, K SUKUMAR, P SURESH, G A BALASUBRAMANIAM, D KANNAN

“…Concurrent infection of chicken anaemia virus (CAV) was also screened by PCR for 419 bp VP2 gene of CAV and found that all the seven flocks which were PCR positive for FAdV also found positive for CAV. Sequencing and phylogenetic analysis of 897 bp FAdV hexon gene revealed that, it was belonged to FAdV serotypes 2 and 3 of species D.…”
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Thioredoxin Reductase-Type Ferredoxin: NADP⁺ Oxidoreductase of <i>Rhodopseudomonas palustris</i>: Potentiometric Characteristics and Reactions with Nonphysiological Oxid... by Mindaugas Lesanavičius, Daisuke Seo, Narimantas Čėnas

“…It is highly possible that the FADH· to FAD oxidation reaction is the rate-limiting step during the reoxidation of reduced FAD. …”
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Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production by Ryota Suzuki, Haruka Takahashi, Chika Yoshida, Masafumi Hidaka, Tomohisa Ogawa, Eugene Futai

“…Study of the mutations that activate and restore the cleavage of FAD mutants is necessary to understand the mechanism of Aβ production. …”
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Genomic Epidemiology and Evolution of Fowl Adenovirus 1 by Szilvia Jakab, Krisztina Bali, Zalán Homonnay, Eszter Kaszab, Katalin Ihász, Enikő Fehér, Tamás Mató, István Kiss, Vilmos Palya, Krisztián Bányai

“…Fowl adenovirus 1 (FAdV-1) is the main cause of gizzard erosion in chickens. …”
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Salinomycin biosynthesis reversely regulates the β‐oxidation pathway in Streptomyces albus by carrying a 3‐hydroxyacyl‐CoA dehydrogenase gene in its biosynthetic gene cluster... by Jiaxiu Wei, Binbin Chen, Jianxin Dong, Xueyu Wang, Yongquan Li, Yingchun Liu, Wenjun Guan

“…Deletion of fadB3 significantly reduced the production of salinomycin. …”
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Visual short-term memory binding deficit in familial Alzheimer's disease by Liang, Y, Pertzov, Y, Nicholas, J, Henley, S, Crutch, S, Woodward, F, Leung, K, Fox, N, Husain, M

“…Twenty individuals with pathological mutations in presenilin 1 or amyloid precursor protein genes for familial Alzheimer's disease (FAD) were tested together with 62 healthy controls. …”

Redox properties of flavocytochrome c3 from Shewanella frigidimarina NCIMB400. by Turner, K, Doherty, M, Heering, H, Armstrong, F, Reid, G, Chapman, S

“…The FAD behaves as a cooperative two-electron center with a pH-dependent reduction potential that is modulated (pKox at 6.5) by ionization of a nearby residue. …”

The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR by Vincent, B, Morellet, N, Fatemi, F, Aigrain, L, Truan, G, Guittet, E, Lescop, E

“…The crystal structures of mammalian and yeast CPRs show a compact organization for the two domains containing FMN (flavin mononucleotide) and FAD (flavin adenine dinucleotide), with a short interflavin distance consistent with fast ET from the NADPH-reduced FAD to the second flavin FMN. …”

Comparative sequence analysis, pathogenicity and immunogenicity of attenuated fowl adenovirus isolates as experimental vaccines against inclusion body hepatitis of commercial broil... by Mohamed Sohaimi, Norfitriah, Bejo, Mohd Hair

“…Introduction: Fowl adenoviruses (FAdV) cause inclusion body hepatitis (IBH) in chickens and new vaccination strategies against IBH are needed as an effective control measure in the poultry industry. …”

Pathogenicity and propagation of UPMT27 field isolate of Malaysia fowl adenovirus in chicken embryo liver cells by Salisu, A., Mat Isa, Nurulfiza, Abdul Razak, Mariatulqabtiah, Bejo, Mohd Hair, Omar, Abdul Rahman, Ideris, Aini

“…The present study was carried out to propagate a field isolate of FAdV (UPM T27) and examine its pathogenicity in chicken egg embryo and chicken embryo liver cells. …”
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Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease by Luis Enrique Arroyo-García, Sara Bachiller, Rocío Ruiz, Antonio Boza-Serrano, Antonio Rodríguez-Moreno, Tomas Deierborg, Yuniesky Andrade-Talavera, André Fisahn

“…We found that the gal3-induced disruption was mediated by the gal3 carbohydrate-recognition domain and prevented by the gal3 inhibitor TD139, which also prevented Aβ42-induced degradation of gamma oscillations. Furthermore, the 5×FAD mice lacking gal3 (5×FAD-Gal3KO) exhibited WT-like gamma network dynamics and decreased Aβ plaque load. …”
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Thwarted belongingness, perceived burdensomeness, and acquired capability for suicide among university students of Bangladesh: Scales validation and status assessment by S. M. Yasir Arafat, Fahad Hussain, Mir Susmita Zaman, Tamanna Tabassum, Md. Khayrul Islam, Farzana Rabin Shormi, Anisur Rahman Khan, Md. Rabiul Islam, A. S. M. Redwan, Noor Ahmed Giasuddin, Anila Mubashir, Md. Abdullah Saeed Khan

“…Confirmatory factor analysis revealed a two-factor structure of Bangla INQ after dropping three items from thwarted belongingness domain (item 9, 11, and 12) and a single factor structure for Bangla ACSS-FAD after dropping three items (item 1, 4, and 6). …”
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A 10-Year Retrospective Study of Inclusion Body Hepatitis in Meat-Type Chickens in Spain (2011–2021) by Kateri Bertran, Angela Blanco, Noelia Antilles, Miquel Nofrarías, Rosa M. Valle, Àlex Cobos, Antonio Ramis, Mar Biarnés, Natàlia Majó

“…A surge in fowl adenovirus (FAdV) causing inclusion body hepatitis (IBH) outbreaks has occurred in several countries in the last two decades. …”
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BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides by John Zhou, Neeraj Singh, James Galske, Jacob Hudobenko, Xiangyou Hu, Riqiang Yan

“…Similar scRNA-seq was also conducted using AD mice with conditional deletion of Bace1 in the adult stage (5xFAD;Bace1 fl/fl ;UBC-creER compared to 5xFAD;Bace1 fl/fl controls). …”
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