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  1. 161

    Most dystrophic neurites in the common 5xFAD Alzheimer mouse model originate from axon terminals by R. Mabrouk, P.O. Miettinen, H. Tanila

    Published 2023-06-01
    “…We utilized a unique feature of the common 5xFAD AD mouse model to test these hypotheses. Cortical layer 5 pyramidal neurons show intracellular APP and Aβ accumulation before amyloid plaque formation while dentate granule cells in these mice show no APP accumulation at any age. …”
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  2. 162

    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ by Kyung Won Jo, Dohyun Lee, Dong Gon Cha, Eunji Oh, Yoon Ha Choi, Somi Kim, Eun Seo Park, Jong Kyoung Kim, Kyong-Tai Kim

    Published 2022-10-01
    “…Results Gossypetin treatment improved the spatial learning and memory of 5xFAD by decreasing Aβ deposition in the hippocampus and cortex of 5xFAD. …”
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  3. 163
  4. 164

    Characterization of Fungal FAD-Dependent AA3_2 Glucose Oxidoreductases from Hitherto Unexplored Phylogenetic Clades by Sudarma Dita Wijayanti, Leander Sützl, Adèle Duval, Dietmar Haltrich

    Published 2021-10-01
    “…The CAZy auxiliary activity family 3 (AA3) comprises FAD-dependent enzymes belonging to the superfamily of glucose-methanol-choline (GMC) oxidoreductases. …”
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  5. 165

    The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer’s Disease by Anna E. Bugrova, Polina A. Strelnikova, Maria I. Indeykina, Alexey S. Kononikhin, Natalia V. Zakharova, Alexander G. Brzhozovskiy, Evgeny P. Barykin, Stanislav I. Pekov, Maria S. Gavrish, Alexey A. Babaev, Anna M. Kosyreva, Anna Y. Morozova, Daniil A. Degterev, Vladimir A. Mitkevich, Igor A. Popov, Alexander A. Makarov, Evgeny N. Nikolaev

    Published 2021-12-01
    “…In the presented work, the accumulation dynamics of Aβ proteoforms in the brain of one of the most widely used amyloid-based mouse models (the 5xFAD line) was monitored. Mass spectrometry (MS) approaches, based on ion mobility separation and the characteristic fragment ion formation, were applied. …”
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  6. 166

    FADS1-arachidonic acid axis enhances arachidonic acid metabolism by altering intestinal microecology in colorectal cancer by Chunjie Xu, Lei Gu, Lipeng Hu, Chunhui Jiang, Qing Li, Longci Sun, Hong Zhou, Ye Liu, Hanbing Xue, Jun Li, Zhigang Zhang, Xueli Zhang, Qing Xu

    Published 2023-04-01
    “…Elimination of gram-negative microbe abolishes FADS1 effect. Mechanistically, gram-negative microbes activate TLR4/MYD88 pathway in CRC cells that contributes FADS1-AA axis to metabolize to prostaglandin E2 (PGE2). …”
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  10. 170

    SNP discovery and structural insights into OeFAD2 unravelling high oleic/linoleic ratio in olive oil by Rayda Ben Ayed, Fabienne Moreau, Hajer Ben Hlima, Ahmed Rebai, Sezai Ercisli, Narendra Kadoo, Mohsen Hanana, Amine Assouguem, Riaz Ullah, Essam A. Ali

    Published 2022-01-01
    “…Fatty Acid Desaturase 2 (FAD2), a key enzyme in the fatty acid biosynthesis pathway, is involved in the desaturation and conversion of oleic acid to linoleic acid. …”
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    DSF inactivator RpfB homologous FadD upregulated in Bradyrhizobium japonicum under iron limiting conditions by Kunal Dutta, Sergey Shityakov, Fumito Maruyama

    Published 2023-05-01
    “…However, significant differences were found between the binding energies of FadD–DSF and RpfB–DSF, indicating possible FadD-dependent DSF turnover. …”
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    Succinate dehydrogenase flavoprotein subunit expression in Saccharomyces cerevisiae--involvement of the mitochondrial FAD transporter, Flx1p. by Giancaspero, T, Wait, R, Boles, E, Barile, M

    Published 2008
    “…The mitochondrial FAD transporter, Flx1p, is a member of the mitochondrial carrier family responsible for FAD transport in Saccharomyces cerevisiae. …”
    Journal article
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    Metod dakwah Mohd Fadli Yusof dalam pengislaman suku kaum masyarakat Murut di pedalaman Sabah by Abd Hadi Borham, Wahyu Hidayat Abdullah, Mohamad Marzuqi Abdul Rahim, Muhammad Akramin Kamaruzaman

    Published 2016
    “…Dalam konteks ini, Mohd Fadli Yusof merupakan seorang pendakwah bebas telah mendekati masyarakat non-muslim khususnya daripada suku kaum Murut di pedalaman Pensiangan Sabah sejak tahun 2011. …”
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