FAK PROTAC Inhibits Ovarian Tumor Growth and Metastasis by Disrupting Kinase Dependent and Independent Pathways by Xueyun Huo, Xueyun Huo, Xueyun Huo, Wenjing Zhang, Guannan Zhao, Guannan Zhao, Zhenwen Chen, Peixin Dong, Hidemichi Watari, Ramesh Narayanan, Ramesh Narayanan, Todd D. Tillmanns, Lawrence M. Pfeffer, Lawrence M. Pfeffer, Junming Yue, Junming Yue

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Focal adhesion kinase inhibition decreases cell viability and induces apoptosis of JAK2 V617F positive cells by Ana Carolina Menezes Mendonça Valente, Gustavo Henrique Lima de Farias, Ana Cristina Ribeiro Bernardo, Caio Cesar de Souza Alves, Michelle Bueno de Moura Pereira, Raquel Tognon-Ribeiro

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Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility by Wang Wenqi, Liu Yang, Liao Kan

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Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects by Ilaria Romito, Manuela Porru, Maria Rita Braghini, Luca Pompili, Nadia Panera, Annalisa Crudele, Daniela Gnani, Cristiano De Stefanis, Marco Scarsella, Silvia Pomella, Stefano Levi Mortera, Emmanuel de Billy, Adrian Libenzio Conti, Valeria Marzano, Lorenza Putignani, Manlio Vinciguerra, Clara Balsano, Anna Pastore, Rossella Rota, Marco Tartaglia, Carlo Leonetti, Anna Alisi

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Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth by Andrea Resovi, Perla Persichitti, Laura Brunelli, Lucia Minoli, Patrizia Borsotti, Giulia Garattini, Matteo Tironi, Erica Dugnani, Miriam Redegalli, Giulia De Simone, Roberta Pastorelli, Maria Rosa Bani, Lorenzo Piemonti, Deane F. Mosher, Raffaella Giavazzi, Giulia Taraboletti, Dorina Belotti

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T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity by Marta Canel, David Taggart, Andrew H Sims, David W Lonergan, Irene C Waizenegger, Alan Serrels

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SIPA1 boosts migration and proliferation, and blocks apoptosis of glioma by activating the phosphorylation of the FAK signaling pathway by Du Yuan, Li Shenglan, Zhou Tong, Zhao Jing, Liu Jiguang

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Direct mechanical exposure initiates hepatocyte proliferation by Wang Li, Yi Wu, Wenhui Hu, Jin Zhou, Xinyu Shu, Xiaoyu Zhang, Ziliang Zhang, Huan Wu, Yu Du, Dongyuan Lü, Shouqin Lü, Ning Li, Mian Long

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Focal adhesion kinase is a phospho-regulated repressor of Rac and proliferation in human endothelial cells by Patrick W. Bryant, Qingxia Zheng, Kevin M. Pumiglia

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A Novel Role for Brain and Acute Leukemia Cytoplasmic (BAALC) in Human Breast Cancer Metastasis by Madeleine Birgersson, Madeleine Birgersson, Mengna Chi, Mengna Chi, Chrissy Miller, Chrissy Miller, Joshua S. Brzozowski, Joshua S. Brzozowski, Jeffrey Brown, Jeffrey Brown, Lachlan Schofield, Lachlan Schofield, Olivia G. Taylor, Olivia G. Taylor, Elizabeth A. Pearsall, Elizabeth A. Pearsall, Jasmine Hewitt, Jasmine Hewitt, Craig Gedye, Craig Gedye, Craig Gedye, Lisa F. Lincz, Lisa F. Lincz, Lisa F. Lincz, Kathryn A. Skelding, Kathryn A. Skelding

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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

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Focal adhesion kinase as a new player in the biology of onco-hematological diseases: the starting evidence by Guido Capasso, Nayla Mouawad, Maria Castronuovo, Edoardo Ruggeri, Andrea Visentin, Livio Trentin, Federica Frezzato

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THSD7A Positivity Is Associated with High Expression of FAK in Prostate Cancer by Fidelis Andrea Flockerzi, Johannes Hohneck, Matthias Saar, Rainer Maria Bohle, Phillip Rolf Stahl

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Rho-associated kinase1 promotes laryngeal squamous cell carcinoma tumorigenesis and progression via the FAK signaling pathway by Liyun Yang, Peipei Qiao, Jianwei Zhang, Shuixian Huang, An Hu

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Focal adhesion kinase–related pathways may be suppressed by metformin in vascular smooth muscle cells in high glucose conditions by Ali Akbar Soleimani, Ghasem Ghasmpour, Asghar Mohammadi, Masoomeh Gholizadeh, Borhan Rahimi Abkenar, Mohammad Najafi

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FAK抑制剂对肝癌HCC-LM3细胞骨架重排和侵袭的作用机制 by 姚红兵, 肖芳, 郭威, 吴嘉兴, 文雪霖, 蒋建晖, 华赟鹏

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Dexamethasone suppresses the proliferation and migration of VSMCs by FAK in high glucose conditions by Ali Akbar Soleimani, Asghar Mohammadi, Ghasem Ghasempour, Borhan Rahimi Abkenar, Nafiseh Shokri, Mohammad Najafi

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Effect of platelet-rich plasma on implant bone defects in rabbits through the FAK/PI3K/AKT signaling pathway by Liu Wei, Chen Ben, Zheng Youyang, Shi Yuehua, Shi Zhuojin

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Genistein Inhibited Estradiol-Induced Vascular Endothelial Cell Injury by Downregulating the FAK/Focal Adhesion Pathway by Bing Liu, Lili Xu, Xinming Yu, Xuefei Jiao, Junwei Yan, Wei Li, Mingjin Guo

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LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition by Eva P. Cuevas, Gema Moreno-Bueno, Giacomo Canesin, Vanesa Santos, Francisco Portillo, Amparo Cano

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