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121
Eastern European Transformation and Youth Attitudes toward Violence
Published 2011-12-01“…</div><div>We find empirical indications that specific features of the family mediate the &ldquo;Eastern effect&rdquo; on the instrumental/utilitarian motive. …”
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122
Epigenetics of Modified DNA Bases: 5-Methylcytosine and Beyond
Published 2018-12-01“…In addition to the ROS1 family mediated demethylation, Ten-Eleven Translocation family proteins-mediated hydroxylation of 5-mC to 5-hydroxymethylcytosine as additional active demethylation pathway are also discussed. …”
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123
Pharmacological Characterization of Purified Full-Length Dopamine Transporter from <i>Drosophila melanogaster</i>
Published 2022-11-01“…The dopamine transporter (DAT) is a member of the neurotransmitter:sodium symporter (NSS) family, mediating the sodium-driven reuptake of dopamine from the extracellular space thereby terminating dopaminergic neurotransmission. …”
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124
Structure of the PfEMP1:EPCR complex and inhibition of the interaction
Published 2015“…<p>The <em>Plasmodium falciparum</em> erythrocyte membrane protein 1 (<em>Pf</em>EMP1) family is central for <em>Plasmodium falciparum</em> infection. This family mediates interactions between the infected erythrocyte and the host endothelial surface, making it an obvious vaccine target. …”
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125
Emerging role of SMYD family of proteins in human tumorigenesis
Published 2023“…In this review, we summarize SMYD family members’ role in different cancers by focusing on their histone and non-histone methylation targets and illustrating the mechanism of SMYD family-mediated oncogenesis.…”
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126
Biomimetic nanotherapy: core–shell structured nanocomplexes based on the neutrophil membrane for targeted therapy of lymphoma
Published 2021-06-01“…DOX combined with SM can enhance the anti-tumor effect, and induce apoptosis of lymphoma cells and inhibit the expression of inflammatory factors related to tumorigenesis depending on the regulation of Bcl-2 family-mediated mitochondrial pathways, such as TNF-α and IL-1β. …”
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127
USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells
Published 2021-12-01“…USP18 and USP20 belong to the ubiquitin-specific protease family, mediating the deubiquitination of targets and promoting antiviral responses. …”
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128
Inhibition of AKT/GSK3β/CREB Pathway Improves the Responsiveness to AMPA Receptor Antagonists by Regulating GRIA1 Surface Expression in Chronic Epilepsy Rats
Published 2021-04-01“…In the present study, we found that both AMPAR antagonists restored the up-regulations of GRIA1 surface expression and Src family-mediated glycogen synthase kinase 3β (GSK3β)-Ca<sup>2+</sup>/cAMP response element-binding protein (CREB) phosphorylations to control levels in responders (whose seizure activities were responsive to AMPAR) but not non-responders (whose seizure activities were uncontrolled by AMPAR antagonists). …”
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129
Targeting the Non-Canonical NF-κB Pathway in Chronic Lymphocytic Leukemia and Multiple Myeloma
Published 2022-03-01“…Taken together, these data suggest that the NIK inhibitor, CW15337, exerts its effects via suppression of the non-canonical NF-κB signaling pathway, which reverses BCL2 family-mediated resistance in the context of CD40L stimulation.…”
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130
A naturally occurring omega current in a Kv3 family potassium channel from a platyhelminth
Published 2008-06-01“…The relative selectivity for different cations is sensitive to specific mutations in the S4 helix,</p> <p>Conclusion</p> <p><it>N.at-K</it><sub><it>v</it></sub><it>3.2</it>, a naturally occurring potassium channel of the Kv3 sequence family, mediates ion permeation through a modified gating pore, not the canonical, highly selective pore typical of potassium channels. …”
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131
Localization and translocation of mature miRNAs
Published 2021-11-01“…It is shown that proteins of the karyopherin family mediate the translocation of miRISC into the cell nucleus. …”
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132
BDNF-TrkB pathway mediates neuroprotection of hydrogen sulfide against formaldehyde-induced toxicity to PC12 cells.
Published 2015-01-01“…As is known to all, Brain-derived neurotropic factor (BDNF), a member of the neurotrophin gene family, mediates its neuroprotective properties via various intracellular signaling pathways triggered by activating the tyrosine kinase receptor B (TrkB). …”
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133
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.
Published 2010-09-01“…The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human endothelium. …”
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134
Fine‐mapping of ZDHHC2 identifies risk variants for schizophrenia in the Han Chinese population
Published 2020-07-01“…Abstract Background ZDHHC2 is a member of the DHHC protein family, mediating palmitoylation of postsynaptic density‐95 (PSD‐95) and A‐kinase‐anchoring protein 79/150 (AKAP79/150). …”
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135
Fumonisin B1 Induces Immunotoxicity and Apoptosis of Chicken Splenic Lymphocytes
Published 2022-05-01“…Altogether, this study reported that FB1 induced the immunotoxicity of chicken splenic lymphocytes and caused splenic lymphocytes apoptosis by the Bcl-2 family-mediated mitochondrial pathway of caspase activation.…”
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136
Analysis of the AMT gene family in chili pepper and the effects of arbuscular mycorrhizal colonization on the expression patterns of CaAMT2 genes
Published 2023-03-01“…Proteins in the ammonium transporter (AMT) family mediate the movement of NH4 + across the cell membrane. …”
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137
Genome-wide identification of DCL, AGO and RDR gene families and their associated functional regulatory element analyses in sunflower (Helianthus annuus).
Published 2023-01-01“…The entire process of RNA interference (RNAi) pathway gene families mediates RNA silencing. The main factors of RNA silencing are the Dicer-Like (DCL), Argonaute (AGO), and RNA-dependent RNA polymerase (RDR) gene families. …”
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138
Does the enterolactone (ENL) affect fatty acid transporters and lipid metabolism in liver?
Published 2017-11-01“…Results ENL stimulated extracellular efflux of free fatty acids (FFA) and triacylglicerols (TAG) to the medium, while, it had no influence on FATP-family mediated intracellular fatty acid uptake. Moreover, ENL decreased the expression of CPT 1, pAMPK, PPARα, increased SREBP1c and had no effect on LXR, and FAS content. …”
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139
Socioeconomic position and self-rated health among female and male adolescents: The role of familial determinants in explaining health inequalities. Results of the German KiGGS stu...
Published 2022-01-01“…In female adolescents, more than 70% of the total effects of each socioeconomic position indicator were explained by familial mediators, whereas no significant direct effects remained. …”
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140
The Acute Phase Reaction and Its Prognostic Impact in Patients with Head and Neck Squamous Cell Carcinoma: Single Biomarkers Including C-Reactive Protein Versus Biomarker Profiles
Published 2020-10-01“…We investigated the systemic levels of interleukin (IL)6 family mediators (glycoprotein (gp130), IL6 receptor (R)α, IL6, IL27, IL31, oncostatin M (OSM), ciliary neurotrophic factor (CNTF)), IL1 subfamily members (IL1R antagonist (A), IL33Rα), and tumor necrosis factor (TNF)α. …”
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