Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precisio... by Mauro Ceccanti, Kenneth Blum, Abdalla Bowirrat, Catherine A. Dennen, Eric R. Braverman, David Baron, Thomas Mclaughlin, John Giordano, Ashim Gupta, Bernard W. Downs, Debasis Bagchi, Debmalya Barh, Igor Elman, Panayotis K. Thanos, Rajendra D. Badgaiyan, Drew Edwards, Mark S. Gold

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Remote and semi-automated methods to conduct a decentralized randomized clinical trial by Teresa Cafaro, Patrick J. LaRiccia, Brigid Bandomer, Helen Goldstein, Tracy L. Brobyn, Krystal Hunter, Satyajeet Roy, Kevin Q. Ng, Ludmil V. Mitrev, Alan Tsai, Denise Thwing, Mary Ann Maag, Myung K. Chung, Noud van Helmond

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Effectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media: study protocol of the OPTIMA pragmatic randomised controlled trial by Paul Little, Alastair D Hay, Lucy Yardley, G Ardine de Wit, Nicolaas P A Zuithoff, Sibyl Anthierens, Roderick P Venekamp, Anne G M Schilder, Roger A M J Damoiseaux, Elisabeth A M Sanders, Saskia Hullegie, Joline L H de Sévaux

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Hypertensive Crisis-Related Hospitalizations and Subsequent Major Adverse Cardiac Events in Young Adults with Cannabis Use Disorder: A Nationwide Analysis by Rupak Desai, Akhil Jain, Waleed Sultan, Zainab Gandhi, Athul Raj Raju, Vivek Joseph Varughese, Geethu Jnaneswaran, Charu Agarwal, Bisharah Rizvi, Zeeshan Mansuri, Puneet Gupta, Gautam Kumar, Rajesh Sachdeva

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Prescription Patterns of New Use of Fixed-Dose Combination Inhalers in Patients with Chronic Obstructive Pulmonary Disease: Long-Acting β2 Agonists Plus Long-Acting Muscarinic... by Liao PA, Pan SW, Chen CY, Deng CY, Dong YH

“…The proportions of LABA/LAMA FDC initiators were more than 30% in the setting of non-primary care clinics (eg, medical centers) and in the services of chest physicians; but were only less than 10% in primary care clinics and non-chest physicians’ services (eg, family medicine physicians). LABA/LAMA FDC initiators appeared to be older, male, to have more comorbidities, and to utilize resources more frequently compared to LABA/ICS FDC initiators.Conclusion: This real-world study found evident temporal trends, variations in healthcare provider, and differences in patient characteristics among COPD patients who initiated LABA/LAMA FDC or LABA/ICS FDC.Keywords: chronic obstructive pulmonary disease, new users, long-acting β 2 agonists/long-acting muscarinic antagonists fixed-dose combination, LABA/LAMA FDC, long-acting β 2 agonists/inhaled corticosteroids fixed-dose combination, LABA/ICS FDC, temporal trends, healthcare provider characteristics, patient characteristics…”
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Substance use and other factors associated with COVID-19 vaccine uptake among people at risk for or living with HIV: Findings from the C3PNO consortium by Marjan Javanbakht, Lamia Khan, Brian Mustanski, Steve Shoptaw, Marianna K. Baum, Shruti H. Mehta, Gregory D. Kirk, Shenghan Lai, Richard Moore, M-J Milloy, Michele Kipke, Kanna Hayashi, Kora DeBeck, Suzanne Siminski, Lisa M White, Pamina Gorbach

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Clinical Characteristics and Predictors of In-Hospital Mortality of Patients Hospitalized with COVID-19 Infection by Leszek Gromadziński, Maciej Żechowicz, Beata Moczulska, Michał Kasprzak, Klaudyna Grzelakowska, Paulina Nowek, Dominika Stępniak, Natalia Jaje-Rykowska, Aleksandra Kłosińska, Mikołaj Pożarowszczyk, Aleksandra Wochna, Adam Kern, Jerzy Romaszko, Agata Sobacka, Przemysław Podhajski, Aldona Kubica, Jacek Kryś, Maciej Piasecki, Piotr Lackowski, Małgorzata Jasiewicz, Eliano Pio Navarese, Jacek Kubica

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Social support, psychosocial risks, and cardiovascular health: Using harmonized data from the Jackson Heart Study, Mediators of Atherosclerosis in South Asians Living in America St... by Jee Won Park, Chanelle J. Howe, Laura A. Dionne, Matthew M. Scarpaci, Belinda L. Needham, Mario Sims, Alka M. Kanaya, Namratha R. Kandula, Joseph L. Fava, Eric B. Loucks, Charles B. Eaton, Akilah J. Dulin

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Association between vitamin D deficiency and the risk of prevalent type 2 diabetes and incident prediabetes: A prospective cohort study using data from The Irish Longitudinal Study... by Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Cathal Walsh, Martin Healy, Annette L. Fitzpatrick, James B. Walsh, Belinda Hernández, Padraic Fallon, Anne M. Molloy, Rose Anne Kenny

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Lessons learned from applying established cut-off values of questionnaires to detect somatic symptom disorders in primary care: a cross-sectional study by Victoria von Schrottenberg, Anne Toussaint, Alexander Hapfelmeier, Alexander Hapfelmeier, Clara Teusen, Bernhard Riedl, Peter Henningsen, Jochen Gensichen, Antonius Schneider, Klaus Linde, Tobias Dreischulte, Peter Falkai, Jochen Gensichen, Peter Henningsen, Markus Bühner, Caroline Jung-Sievers, Helmut Krcmar, Karoline Lukaschek, Gabriele Pitschel-Walz, Antonius Schneider, Jochen Vukas, Puya Younesi, Feyza Gökce, Victoria von Schrottenberg, Petra Schönweger, Hannah Schillock, Jonas Raub, Philipp Reindl-Spanner, Lisa Hattenkofer, Lukas Kaupe, Carolin Haas, Julia Eder, Vita Brisnik, Constantin Brand, Chris Ebert, Marie Emilia Vogel, Clara Teusen, Katharina Biersack

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Effectiveness of COVID-19 vaccines against severe outcomes in cancer patients: Real-world evidence from self-controlled risk interval and retrospective cohort studies by Hui-Eon Lee, Na-Young Jeong, Minah Park, Eunsun Lim, Jeong Ah Kim, Heehyun Won, Chung-Jong Kim, Sang Min Park, Nam-Kyong Choi

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CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes by Oliver Schnell, Tadej Battelino, Richard Bergenstal, Andreas L. Birkenfeld, Antonio Ceriello, Alice Cheng, Melanie Davies, Steve Edelman, Thomas Forst, Francesco Giorgino, Jennifer Green, Per-Henrik Groop, Samy Hadjadj, Hiddo J.L.Heerspink, Marcus Hompesch, Baruch Izthak, Linong Ji, Naresh Kanumilli, Boris Mankovsky, Chantal Mathieu, Martin Miszon, Reem Mustafa, Michael Nauck, Roberto Pecoits-Filho, Jeremy Pettus, Kari Ranta, Helena W. Rodbard, Peter Rossing, Lars Ryden, Petra-Maria Schumm-Draeger, Scott D. Solomon, Jan Škrha, Pinar Topsever, Tina Vilsbøll, John Wilding, Eberhard Standl

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Évaluation du risque de dysglycémie dans la région de Kitikmeot (Nunavut) au moyen de l'outil CANRISK by Ying Jiang, Susan Rogers Van Katwyk, Yang Mao, Heather Orpana, Gina Agarwal, Margaret de Groh, Monique Skinner, Robyn Clarke, Howard Morrison

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Acute otitis media management: A survey of European primary care pediatricians by Guadalupe Del Castillo-Aguas, César García-Vera, Jacob Urkin, Marilena Moretto, Mareja Vintar Spreitzer, Pirkko Keronen, Andreas Werner, Laura Reali, Karin Geitmann, Péter Poloskey, Beata Kartousova, Werner Sauseng, Mario Schumacher, Stephen Reingold, Concepción Sánchez-Pina

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Effect Modification by Social Determinants of Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions within an Integrated U.S. Healthcare System by Loren Saulsberry, Lavisha Singh, Jaclyn Pruitt, Christopher Ward, Dyson T. Wake, Robert D. Gibbons, David O. Meltzer, Peter H. O’Donnell, Wanda Cruz-Knight, Peter J. Hulick, Henry M. Dunnenberger, Sean P. David

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Influence of comorbid heart disease on dyspnea and health status in patients with COPD – a cohort study by Giezeman M, Hasselgren M, Lisspers K, Ställberg B, Montgomery S, Janson C, Sundh J

“…Maaike Giezeman,1,2 Mikael Hasselgren,1 Karin Lisspers,3 Björn Ställberg,3 Scott Montgomery,4–6 Christer Janson,7 Josefin Sundh8 1School of Medical Sciences, Örebro University, Örebro, Sweden; 2Centre for Clinical Research, County Council of Värmland, Karlstad, Sweden; 3Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden; 4Clinical Epidemiology and Biostatistics, Örebro University, Örebro, Sweden; 5Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden; 6Department of Epidemiology and Public Health, University College, London, UK; 7Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden; 8Department of Respiratory Medicine, School of Medical Sciences, Örebro University, Örebro, Sweden Purpose: The aim of this study was to examine the changing influence over time of comorbid heart disease on symptoms and health status in patients with COPD. …”
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Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co‐Metabolism in Patients With Alcoholic Hepatitis by Bei Gao, Yi Duan, Sonja Lang, Dinesh Barupal, Tsung‐Chin Wu, Luis Valdiviez, Bryan Roberts, Ying Yng Choy, Tong Shen, Gregory Byram, Ying Zhang, Sili Fan, Benjamin Wancewicz, Yan Shao, Kevin Vervier, Yanhan Wang, Rongrong Zhou, Lu Jiang, Shilpa Nath, Rohit Loomba, Juan G. Abraldes, Ramon Bataller, Xin M. Tu, Peter Stärkel, Trevor D. Lawley, Oliver Fiehn, Bernd Schnabl

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Differential risk of 23 site‐specific incident cancers and cancer‐related mortality among patients with metabolic dysfunction‐associated fatty liver disease: a population‐based coh... by Goh Eun Chung, Su Jong Yu, Jeong‐Ju Yoo, Yuri Cho, Kyu‐na Lee, Dong Wook Shin, Yoon Jun Kim, Jung‐Hwan Yoon, Kyungdo Han, Eun Ju Cho

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The Attitudes and Practices Regarding COVID-19 among General Practitioners from Croatia and Bosnia and Herzegovina: A Cross-Sectional Study by Zudi Osmani, Almina Bajrektarevic Kehic, Ivan Miskulin, Lea Dumic, Nika Pavlovic, Jelena Kovacevic, Vedrana Lanc Curdinjakovic, Juraj Dumic, Ivan Vukoja, Maja Miskulin

“…Considering GPs’ practices regarding COVID-19 prevention and control, among the Croatian GPs, more positive practices were reported by older GPs (<i>p</i> = 0.008), females (<i>p</i> = 0.002), GPs who had a partner (<i>p</i> = 0.021), GPs who were specialists in family medicine (<i>p</i> = 0.014), GPs with a longer length of service (<i>p</i> = 0.007), and GPs who had finished a formal education on the prevention of infectious diseases and occupational safety (<i>p</i> = 0.046), while among the Bosnian GPs, no significant correlations were determined. …”
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Leisure time television watching, computer use and risks of breast, colorectal and prostate cancer: A Mendelian randomisation analysis by Nikos Papadimitriou, Nabila Kazmi, Niki Dimou, Konstantinos K. Tsilidis, Richard M. Martin, Sarah J. Lewis, Brigid M. Lynch, Michael Hoffmeister, Sun‐Seog Kweon, Li Li, Roger L. Milne, Lori C. Sakoda, Robert E. Schoen, Amanda I. Phipps, Jane C. Figueiredo, Ulrike Peters, Suzanne C. Dixon‐Suen, Marc J. Gunter, Neil Murphy

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