Preclinical study in a postoperative pain model to investigate the action of ketamine, lidocaine, and ascorbic acid in reversing fentanyl-induced, non–glutamate-dependent hyperalgesia by Marina Ayres Delgado, Luana Assis Ferreira, Bianka Jaciara dos Santos Gomes, Isis Katarine Orlandi Leite, Marcus Vinícius Gomez, Célio Castro-Junior

“…Increased glutamate release was not the main molecular mechanism of fentanyl-induced hyperalgesia.…”
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Developing and Evaluating the Greenness of a Reliable, All-in-One Thin-Film Microextraction Protocol for Determining Fentanyl, Methadone, and Zolpidem in Plasma, Urine, and Oral Fluid by Krzysztof Goryński, Łukasz Sobczak, Dominika Kołodziej

“…This paper proposes an all-in-one microextraction-based protocol capable of determining and quantifying fentanyl, methadone, and zolpidem in plasma, urine, and saliva at concentrations below those required by international regulatory organizations. …”
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An open label randomized controlled trial on the efficacy of adding intranasal fentanyl to intravenous tramadol in patients with moderate to severe pain following acute musculoskeletal injuries by Shaharudin , Abdul Aziz

“…Intra-nasal fentanyl, as an alternative route of analgesic administration, has been shown to be effective particularly in pediatric population and in prehospital setting. …”
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Combined spinal epidural analgesia in labor: comparison of intrathecal 2mg plain bupiv a caine versus heavy bupiv a caine with fentanyl by Ahmad Nizam, Ismail

“…Group I patients received 2 mg plain intrathecal bupivacaine with 25mcg fentanyl and group 2 received 2 mg intrathecal heavy bupivacaine with 25 meg fentanyl .The pain was assessed on the variables at time 0 (time at the start of IT injection) and at 5, 15,30 min. …”
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Comparison of the Efficacy of Intrathecal Fentanyl 20mcg versus Intrathecal Morphine 0.2 mg as an adjuvant therapy in spinal anesthesia in lower limb surgery by May, Lee Jun

“…They were divided into 2 groups; Patient in ITF group receive 2.8mls of 0.5% hyperbaric bupivacaine with 20mcg of fentanyl added whilst patient in ITM group received 2.8mls of 0.5% hyperbaric bupivacaine with 0.2 mg of morphine added. …”
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The Effect of Adding Dexmedetomidine to Fentanyl for Pain Management after Spinal Fusion Surgery Using Intravenous Patient-Controlled Analgesia Pumps; A Clinical Trial Study by Mojtaba Rahimi-Varposhti, Mehdi Izadi-Zamanabadi

“…Methods: Patients undergoing spine surgeries were randomly categorized into two groups of fentanyl + dexmedetomidine and fentanyl + placebo. …”
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Incidence of Intraoperative Hypotension and Bradycardia in Spinal Anaesthesia with 0.5% Bupivacaine alone and 0.5% Bupivacaine with Fentanyl for Abdominal Hysterectomy: A Cross-sectional Study by Swathy Sudan, Remani Kelan Kamalakshy, Sunil Raveendran, Ranju Sebastian

“…Aim: To compare the incidence of intraoperative hypotension, bradycardia and its side-effects when using 0.5% hyperbaric bupivacaine alone and with 25 μg fentanyl added to it for subarachnoid block for abdominal hysterectomy. …”
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Comparative efficacy of serratus anterior plane block (SAPB) and fentanyl for postoperative pain management and stress response in patients undergoing minimally invasive cardiac surgery (MICS) by Sengupta Saikat, Singh Shweta, Mukherjee Somalia, Khan Dibyendu, Mukhopadhyay Sushan

“…SAPB group (Group A) patients were given 0.2% of 20 ml ropivacaine followed by catheter insertion for continuous infiltration at the end of the procedure. Fentanyl group (Group B) patients were given fentanyl infusion for postoperative analgesia. …”
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Comparison of impact of adjuvant treatment of midazolam, fentanyl, and magnesium sulfate with intrathecal bupivacaine on block characteristics and postoperative analgesia in knee arthroplasty: A randomized clinical trial by Hesameddin Modir, Esmail Moshiri, Mehran Azami, Tayebe Sadat Sayafi-Sharifi

Subjects: “…block characteristics; bupivacaine; fentanyl; hemodynamic changes; intrathecal; magnesium sulfate; midazolam…”
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Effects of Esmolol, Lidocaine and Fentanyl on P Wave Dispersion, QT, QTc Intervals and Hemodynamic Responses to Endotracheal Intubation During Propofol Induction: a Comparative Study by Volkan Hancı, Serhan Yurtlu, Turgut Karabağ, Dilek Okyay, Sedat Hakimoğlu, Gülay Kayhan, Çağatay Büyükuysal, Hilal Ayoğlu, Işıl Özkoçak Turan

“…The control group (Group C) received saline 5 mL, the esmolol group (Group E) received esmolol 0.5 mg.kg-1, the fentanyl group (Group F) received fentanyl 2 μg.kg-1 and the lidocaine group (Group L) received lidocaine 1.5 mg.kg-1 before anesthesia induction. …”
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Comparison of onset of action of Intrathecal Clonidine vs Intrathecal Fentanyl as an adjuvant with hyperbaric Bupivacaine and Bupivacaine alone under spinal anesthesia for lower limb orthopedic surgeries by Aradhana Devi, Amrita Santosh, Archana Har, Jessy Vennel, Vikrant Gadkari

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Aperçu - Surdoses de furanyl-fentanyl causées par l'usage de crack contaminé — Colombie-Britannique (Canada), 15 au 18 juillet 2016 by S. A. Klar, E. Brodkin, E. Gibson, S. Padhi, C. Predy, C. Green, V. Lee

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Comparison of the effects of etomidate combined with sufentanil, fentanyl, or dezocine on the consciousness index and adverse reactions for painless gastroscopy: A randomized controlled single-blinded pilot study by Ji Liu, Ming Sun, Weiwu Fang, Changqing Zhong, Xuewu Xu, Yan Lv, Lin Zhao, Qiang Li, Ying Zhang, Ming Zou, Yong Wang, Xiaochen Wang

“…Objective: To use etomidate in combination with different opioids (sufentanil, fentanyl, and dezocine) to compare several anesthesia options from the aspects of the patient's index of consciousness (IoC). …”
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Comparison of the effects of midazolam, dexamethasone, ondansetron and propofol on the prevention and control of opioid-induced pruritus after spinal anaesthesia with bupivacaine combined with fentanyl in femoral fracture surgery by Hesameddin Modir, Esmail Moshiri, Mehran Azami, Amirreza Modir

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A study to evaluate the efficacy of instillation of ropivacaine with fentanyl, dexmedetomidine, or morphine through surgical drain for post-operative analgesia in patients undergoing modified radical mastectomy by Sumit Das, Pritam Yadav, Sanjay Johar, Naveen Malhotra, Irin Saha, Ritu Rathee

“…Aims and Objectives: This study was conducted to evaluate the efficacy of instillation of ropivacaine with fentanyl, dexmedetomidine or morphine through surgical drain for post-operative analgesia and patient satisfaction in patients undergoing modified radical mastectomy. …”
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Cardiorespiratory consequences of attenuated fentanyl and augmented rocuronium dosing during protocolised prehospital emergency anaesthesia at a regional air ambulance service: a retrospective study by Sarah Morton, Zoey Spurgeon, Charlotte Ashworth, James Samouelle, Peter B Sherren

“…Many prehospital teams have adopted a drug regimen of 3 mcg/kg fentanyl, 2 mg/kg ketamine and 1 mg/kg rocuronium (‘3:2:1’). …”
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Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway by Hong-Fang Yang, Ming Yu, Hui-Dan Jin, Jia-Qi Yao, Zhi-Li Lu, Iddrisu B. Yabasin, Qiu Yan, Qing-Ping Wen

Subjects: “…fentanyl…”
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Careful Breakthrough Cancer Pain Treatment through Rapid-Onset Transmucosal Fentanyl Improves the Quality of Life in Cancer Patients: Results from the BEST Multicenter Study by Arturo Cuomo, Marco Cascella, Cira Antonietta Forte, Sabrina Bimonte, Gennaro Esposito, Stefano De Santis, Luigi Cavanna, Flavio Fusco, Mario Dauri, Silvia Natoli, Marco Maltoni, Alessandro Morabito, Rocco Domenico Mediati, Vito Lorusso, Sandro Barni, Giampiero Porzio, Sebastiano Mercadante, Anna Crispo

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Analgesic Efficacy of Nefopam as an Adjuvant in Patient-Controlled Analgesia for Acute Postoperative Pain After Laparoscopic Colorectal Cancer Surgery by Eun Jung Oh, Woo Seog Sim, Won Gook Wi, Jeayoun Kim, Woo Jin Kim, Jin Young Lee

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Attenuation of hemodynamic pressor response to laryngoscopy and endotracheal intubation by intravenous fentanyl in elective surgery under general anesthesia: A randomized controlled trial using three different doses by Rajdip Hazra, Yarilang Rozanna Syiem, Sanjay Maitra, Sisir Chakraborty, Manabendra Sarkar

Subjects: “…fentanyl; direct laryngoscopy; endotracheal intubation; hemodynamic pressor response…”
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