Recommendations from people who use drugs in Philadelphia, PA about structuring point-of-care drug checking by Megan K. Reed, Elias Borne, Tracy Esteves Camacho, Morgan Kelly, Kristin L. Rising

“…Abstract Background Adulterants, such as fentanyl and xylazine, among others, are present in a high percentage of the illicit drug supply, increasing the risk for overdose and other adverse health events among people who use drugs (PWUD). …”
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Randomized controlled trial of the effect of general anesthetics on postoperative recovery after minimally invasive nephrectomy by Hyun-Kyu Yoon, Somin Joo, Susie Yoon, Jeong-Hwa Seo, Won Ho Kim, Ho-Jin Lee

“…However, there were no significant differences in other outcomes, except for fentanyl consumption, within the first 24 h postoperatively. …”
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Evaluating the perioperative analgesic effect of ultrasound-guided trigeminal nerve block in adult patients undergoing maxillofacial surgery under general anesthesia: A randomized... by Maha Misk, Abdelrhman Alshawadfy, Medhat Lamei, Fatma Khames, Mohamed Abd Elgawad, Hamdy A. Hendawy

“…Total intraoperative fentanyl consumption was the primary outcome. The secondary outcomes were the intraoperative hemodynamic parameters besides the postoperative pain, total opioid consumption, complications, and patient satisfaction.Results Compared to general anesthesia, USGTNB significantly reduced the intraoperative fentanyl consumption (2.38 ± 0.62 vs 0.36 ± 0.55, p < 0.001), and the intraoperative heart rate and mean arterial blood pressure at 1, 2, and 3 h (p < 0.001), the numerical rating score during the 24 postoperative hours (p < 0.001), and the postoperative nalbuphine consumption (11.60 ± 4.72 vs 1.92 ± 3.28, p < 0.001). …”
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Sedation effects by dexmedetomidine versus propofol in decreasing duration of mechanical ventilation after open heart surgery by Ahmed Said Elgebaly, Mohab Sabry

“…There was significant difference between both the groups in midazolam and fentanyl dose requirement and financial costs with a value of P < 0.05. …”
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Continuous flow Aza-Michael reaction for preparing the fast-acting synthetic opioid drug Remifentanil by Artur de Lara Lima Vaz, João Luis Callegari Lopes, Giuliano Cesar Clososki

“…Abstract Remifentanil is a modern fentanyl analogue with ultrashort-action granted by an esterase-labile methyl propanoate chain. …”
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Anestesia Spinal untuk Seksio Sesarea pada Pasien Hipotiroid by Rizqi Adhelia, Sri Rahardjo, Yusmein Uyun

“…Anestesia spinal dilakukan dengan bupivakain 0,5% 7,5 mg dan fentanyl 25 µg. Bayi lahir dengan skor Apgar 8/9, hemodinamik stabil selama operasi. …”
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STING controls opioid-induced itch and chronic itch via spinal tank-binding kinase 1-dependent type I interferon response in mice by Nan Li, Chunyan Wang, Yuying Zhao, Yigang Wang, Tianyu Gao, Yonghao Yu, Guolin Wang, Linlin Zhang

“…Methods Opioids (morphine, fentanyl and sufentanil) were intrathecally injected to induce acute itch. …”
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Pharmacovigilance Signals of the Opioid Epidemic over 10 Years: Data Mining Methods in the Analysis of Pharmacovigilance Datasets Collecting Adverse Drug Reactions (ADRs) Reported... by Stefania Chiappini, Rachel Vickers-Smith, Amira Guirguis, John M. Corkery, Giovanni Martinotti, Daniel R. Harris, Fabrizio Schifano

“…Compared with other opioids, abuse concerns were mostly recorded in relation to fentanyl and oxycodone, while tramadol and oxycodone were more strongly associated with drug dependence and withdrawal. …”
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Efficacy of a local anesthetic gel infusion kit for pain relief after minimally invasive colorectal surgery: an open-label, randomized clinical trial by Jung Kyong Shin, Heejoon Jeong, Woo Yong Lee, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Woo Seog Sim, Hee Cheol Kim

“…There was no significant difference in the total usage of fentanyl between the two groups (Gel group, 1623.98 mcg; On-Q group, 1595.12 mcg; P = 0.806). …”
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Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by V. V. Moroz, V. T. Dolgikh, S. A. Karpitskaya

“…Premedication with atropine and promedol was given, and anesthesia induction was carried out with propofol, fentanyl and suxamethonium. Sevoflurane, fentanyl andcisatracurium were employed to maintain anesthesia, analgesia and myorelaxation, respectively. …”
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Quadratus lumborum block (transmuscular approach) versus transversus abdominis plane block (unilateral subcostal approach) for perioperative analgesia in patients undergoing open n... by Amany H. Saleh, Mai W. Abdallah, Ashraf M. Mahrous, Norhan A. Ali

“…Results: Intraoperative fentanyl consumption (μg) was significantly lower in Groups A and B (164.69 ± 27.35 and 190.31 ± 44.48, respectively) than in Group C (347.50 ± 63.64) (p < 0.001). …”
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Combined Spinal-Epidural Anesthesia with Isobaric Ropivacaine 0.375% for Inguinal Hernia Surgery in a Heart Failure Patient with Ejection Fraction of 36% by Muhammad Isra Rafidin Rayyan, Salman Sultan Ghiffari, Achmad Hariyanto, Achmad Wahib Wahju Winarso, Haris Darmawan, Ichlasul Mahdi Fardhani

“…Spinal anesthesia was performed with isobaric ropivacaine 0.375% and fentanyl 25 μg in a total volume of 3.5 ml at the L3-L4 intervertebral space. …”
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A sudden increase in heart rate during ablation of the right superior pulmonary venous vestibule is correlated with pain-relief in patients undergoing atrial fibrillation ablation by Ping Fang, Xianghai Wang, Meijun Zhang, Jichun Liu, Youquan Wei, Jinfeng Wang, Hao Yang, Xiangrong Xie, ShengXing Tang

“…The VAS score [2.3 (1.3–3.4) vs. 6.0 (4.4–6.9); p ≤ 0.001)] and the amount of fentanyl used (107 ± 12 vs. 172 ± 26 ug; p ≤ 0.001) were significantly lower in the R group. …”
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Associations between opioid overdose deaths and drugs confiscated by law enforcement and submitted to crime laboratories for analysis, United States, 2014–2019: an observational st... by Jon E. Zibbell, Arnie Aldridge, Megan Grabenauer, David Heller, Sarah Duhart Clarke, DeMia Pressley, Hope Smiley McDonald

“…In addition, 3,817,438 forensic laboratory reports in the US that were reported to NFLIS-Drug contained an opioid, stimulant, or benzodiazepine. Reports of fentanyl and fentanyl-related compounds (FFRC) had the strongest association with OOD. …”
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Opioid-induced respiratory depression and risk factors in a tertiary hospital: A retrospective study by Nabil A. Almouaalamy, Majed Alshamrani, Waleed K. Alnejadi, Ziyad M. Alharbi, Faisal M. Aldosari, Enad F. Alsulimani, Saif A. Saif, Mohammed K. Aldawsari

“…Conclusion: In conclusion, monitoring patient receiving opioids with a daily MME dose of ≥150 MME, prescribed Fentanyl, low urea concentration at the baseline, and patients’ admissions to the surgery department may mitigate the risk of developing OIRD.…”
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Comparison of Efficacy of Erector Spinae Plane Block with Paravertebral Block for Postoperative Analgesia in Patients Undergoing Breast Cancer Surgery by Arjun Singh, Nidhi Agrawal, Udismita Baruah, Surabhi Sandill

“…Both the groups were comparable in terms of fentanyl requirement and total 24 hours tramadol requirement Other parameters like postoperative nausea vomiting, effect on hemodynamic and overall patient satisfaction were also comparable between the two groups. …”
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Analgesic effect of epidural anesthesia via the intervertebral foramen approach in percutaneous transforaminal endoscopic discectomy: a retrospective study by Jingyue Zhang, Xueyao Wang, Zhenhua Cai, Jiyu Kang, Yongliang Liu, Chunyan Nie, Huacheng Zhou

“…MAP and HR values in the LTEA group were significantly lower than those in the LA group (P < 0.05). The total dose of fentanyl in the LTEA group was significantly lower than that in the LA group (P < 0.05). …”
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Comparison of Early Postoperative Recovery after Desflurane or Sevoflurane Anesthesia by Özlem Sezen, Elif Bombacı

“…Following the intravenous (IV) administration of 5 to 7 mg/kg thiopental and 1 mcg/kg fentanyl, 0.6 mg/kg rocuronium was used to facilitate endotracheal intubation. …”
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Comparing the efficacy ultrasound guided bilateral transversus abdominis plane (TAP) block between 0.25% bupivacaine versus 0.125% bupivacaine in laparoscopic appendicectomy by Zulkipeli, Zubaidah

“…The visual analogue pain score (VAS) were assessed at 30 minutes, 4H, 8H, 16H and 24H post operation. Total PCA fentanyl requirement were compared between these two groups. …”
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Comparison of analgesic efficacy between preemptive intravenous paracetamol and single shot caudal block in paediatric inguinal hernia repair by Othman, Siti Sarah

“…Keberkesanan analgesik paracetamol yang diberi melaui vena adalah sama dengan pembiusan setempat ‘caudal block’ jika dikira dari perspektif masa pertama permintaan ubat tahan sakit dan juga jumlah penggunaan fentanyl.…”
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