The Dilemma of Cure and Damage in Oligodendroglioma: Ways to Tip the Balance Away from the Damage by Ruurd Torensma

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The Chromatin-Oxygen Sensor Gene <i>KDM5C</i> Associates with Novel Hypoxia-Related Signatures in Glioblastoma Multiforme by Denise Drongitis, Lucia Verrillo, Pasqualino De Marinis, Pasquale Orabona, Agnese Caiola, Giacinto Turitto, Alessandra Alfieri, Sara Bruscella, Marisa Gentile, Vania Moriello, Ettore Sannino, Ines Di Muccio, Valerio Costa, Maria Giuseppina Miano, Alberto de Bellis

Subjects: “…5-aminolevulinic acid fluorescence-guided surgery (5-ALA FGS)…”
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Indocyanine Green Fluorescence-Guided Knee Arthroscopy: A Technical Note for Investigating the Microvasculature Around the Meniscus by Tamiko Kamimura, M.D., Ph.D.

“…In this Technical Note, the author applied ICG fluorescence-guided surgery to knee arthroscopy to evaluate blood supply to the meniscus and intra-articular apparatus. …”
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High-Power, Computer-Controlled, Light-Emitting Diode–Based Light Sources for Fluorescence Imaging and Image-Guided Surgery by Sylvain Gioux, Vida Kianzad, Razvan Ciocan, Sunil Gupta, Rafiou Oketokoun, John V. Frangioni

“…For image-guided surgery, in particular fluorescence-guided surgery, a high fluence rate, a long working distance, computer control, and precise control of wavelength are required. …”
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Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models. by Jeong Youp Park, Takashi Murakami, Jin Young Lee, Yong Zhang, Robert M Hoffman, Michael Bouvet

“…The present study thus demonstrates that fluorophore-conjugated IGF-1R antibodies selectively visualize metastatic colon cancer and have clinical potential for improved diagnosis and fluorescence-guided surgery.…”
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Intraoperative fluorescence imaging for personalized brain tumor resection: Current state and future directions by Evgenii Belykh, Nikolay Martirosyan, Kaan Yagmurlu, Eric Miller, Jennifer Eschbacher, Mohammadhassan Izadyyazdanabadi, Liudmila Bardonova, Vadim Byvaltsev, Peter Nakaji, Mark Preul

“…Introduction: Fluorescence-guided surgery is one of the rapidly emerging methods of surgical theranostics. …”
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Advances in the intraoperative delineation of malignant glioma margin by Shan Jiang, Huihui Chai, Qisheng Tang

“…Here, we introduced four intraoperative technologies to delineate malignant glioma margin, namely, magnetic resonance imaging, fluorescence-guided surgery, Raman histology, and mass spectrometry. …”
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Improved Diagnostic Imaging of Brain Tumors by Multimodal Microscopy and Deep Learning by Johanna Gesperger, Antonia Lichtenegger, Thomas Roetzer, Matthias Salas, Pablo Eugui, Danielle J. Harper, Conrad W. Merkle, Marco Augustin, Barbara Kiesel, Petra A. Mercea, Georg Widhalm, Bernhard Baumann, Adelheid Woehrer

“…Fluorescence-guided surgery is a state-of-the-art approach for intraoperative imaging during neurosurgical removal of tumor tissue. …”
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Translation of c-Met Targeted Image-Guided Surgery Solutions in Oral Cavity Cancer—Initial Proof of Concept Data by Tessa Buckle, Maarten van Alphen, Matthias N. van Oosterom, Florian van Beurden, Nina Heimburger, Jaqueline E. van der Wal, Michiel van den Brekel, Fijs W. B. van Leeuwen, Baris Karakullukcu

“…Ex vivo evaluation of tumor specimens suggests that c-Met is a possible candidate for fluorescence-guided surgery in oral cavity cancer.…”
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Intraoperative fluorescence-guided resection of high-grade glioma: A systematic review by Lin Yang, Yan Xiang, Guo-Hao Huang, Hong-Yao Lyu, Ke-Jie Mou, Sheng-Qing Lv

“…However, further prospective, multicenter, randomized controlled trials are still in need to prove the advantage of fluorescence-guided surgery on patients' OS/PFS.…”
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Nanoparticles for multimodal in vivo imaging in nanomedicine by Key J, Leary JF

“…By combining different imaging modalities, we can start with deep-body imaging by magnetic resonance imaging or computed tomography, and by using optical imaging, get down to the resolution required for real-time fluorescence-guided surgery.Keywords: nanomedicine, nanoparticles, multimodal imaging, CT, MRI, NIRF, PET, cancer…”
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Significance of Second Near-Infrared Region (NIR-II) guided tumor detection and surgical treatment using Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEACAM) targeted p... by Fiza Mushtaq, Haneen Kamran

“…Near-infrared fluorescence-guided surgery, a rapidly evolving technique, enables surgeons to assess tumour borders of various cancer types and lesions of other prevalent illnesses with great precision. …”
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Evaluation of a novel ovarian cancer-specific fluorescent antibody probe for targeted near-infrared fluorescence imaging by Junchen Chen, Chen Zhang, Yanxiu Guo, Xiaohong Chang, Ruiqiong Ma, Xue Ye, Hongyan Cheng, Yi Li, Heng Cui

“…Abstract Background To meet clinical needs, fluorescence-guided surgery has emerged as a new technique that guides surgeons in the resection of cancerous tissue by highlighting tumour lesions during surgery. …”
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Significance of Second Near-Infrared Region (NIR-II) guided tumor detection and surgical treatment using Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEACAM) targeted p... by Fiza Mushtaq, Haneen Kamran

“…Near-infrared fluorescence-guided surgery, a rapidly evolving technique, enables surgeons to assess tumour borders of various cancer types and lesions of other prevalent illnesses with great precision. …”
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Medication-related osteonecrosis of the jaw treatment modalities: A review by Amir Ali Asadi

“…Surgery should be considered in all stages of MRONJ as it confirms the histology. Fluorescence-guided surgery is helpful for MRONJ cases under Denosumab and it is recommended to use low level laser and PDT as adjuvant treatment of MRONJ. …”
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Nephron-sparing surgery for Wilms tumor by Andrew J. Murphy, Andrew J. Murphy, Andrew M. Davidoff, Andrew M. Davidoff

“…We will review technical aspects of the conduct of nephron-sparing surgery for synchronous bilateral Wilms tumor, including the more recent advances in the use of imaging adjuncts such as pre-operative 3D imaging and fluorescence-guided surgery. The potential role of nephron-sparing surgery for unilateral Wilms tumor will also be discussed.…”
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Development of a Simulation Model for Fluorescence-Guided Brain Tumor Surgery by Daniel Valli, Evgenii Belykh, Xiaochun Zhao, Sirin Gandhi, Claudio Cavallo, Nikolay L. Martirosyan, Peter Nakaji, Michael T. Lawton, Mark C. Preul

“…They are useful educational tools for teaching the key concepts of intra-axial tumor resection techniques, such as subpial dissection and nuances of fluorescence-guided surgery.…”
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Fluorescent Thienothiophene-Containing Squaraine Dyes and Threaded Supramolecular Complexes with Tunable Wavelengths between 600–800 nm by Wenqi Liu, Hannah H. McGarraugh, Bradley D. Smith

“…A broad range of practical applications is envisioned in healthcare diagnostics, microscopy, molecular imaging, and fluorescence-guided surgery.…”
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Radiolabeled PSMA Inhibitors by Oliver C. Neels, Klaus Kopka, Christos Liolios, Ali Afshar-Oromieh

“…We have reviewed developments in the field of radio- and fluorescence-guided surgery and targeted photodynamic therapy as well as multitargeting PSMA inhibitors also addressing albumin, GRPr and integrin α_vβ₃. …”
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Improving the extent of malignant glioma resection by dual intraoperative visualization approach. by Ilker Y Eyüpoglu, Nirjhar Hore, Nic E Savaskan, Peter Grummich, Karl Roessler, Michael Buchfelder, Oliver Ganslandt

“…In this context, two established methods for tumor visualization, fluorescence guided surgery with 5-ALA and intraoperative MRI (iMRI) with integrated functional neuronavigation were investigated as a dual intraoperative visualization (DIV) approach. …”
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