Neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets by Nodal, FR, Leach, ND, Keating, P, Dahmen, JC, Zhao, D, King, AJ, Bajo, VM

Expression of complexin I and II mRNAs and their regulation by antipsychotic drugs in the rat forebrain. by Eastwood, S, Burnet, P, Harrison, P

“…We characterized the distribution of cx I and II mRNAs in rat forebrain and examined whether their abundance, or the transcript of the synaptic marker synaptophysin, is affected by 14 days' administration of antipsychotic drugs (haloperidol, chlorpromazine, risperidone, olanzapine, or clozapine). …”

Glutaminase 1 deficiency confined in forebrain neurons causes autism spectrum disorder-like behaviors by Chenhui Ji, Yalin Tang, Yanyan Zhang, Xiaoyan Huang, Congcong Li, Yuhong Yang, Qihui Wu, Xiaohuan Xia, Qingyuan Cai, Xin-Rui Qi, Jialin C. Zheng

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Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors by Ling Ma, Yuting Mei, Peibo Xu, Yan Cheng, Zhiwen You, Xiaoli Ji, Deyi Zhuang, Wenhao Zhou, Yuejun Chen, Man Xiong

“…Here, we presented evidence that overexpression of SOX10 and OLIG2 (SO) in human embryonic stem cells (hESCs)-derived ventral forebrain neural progenitors is sufficient to produce forebrain pre-oligodendrocytes (pre-OLs) and mature oligodendrocytes (OLs) within 20–40 days. …”
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Forebrain Ischemia-Reperfusion Simulating Cardiac Arrest in Mice Induces Edema and DNA Fragmentation in the Brain by Christina H. Liu, Shuning Huang, Young R. Kim, Bruce R. Rosen, Philip K. Liu

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Olfactory tubercle stimulation alters odor preference behavior and recruits forebrain reward and motivational centers by Brynn J FitzGerald, Kara eRichardson, Daniel W. Wesson

“…Perhaps providing a foundation for this modulation in behavior, we found that OT stimulation significantly increased the number of c-Fos positive neurons in not only the OT, but also in forebrain structures essential to motivated behaviors, including the nucleus accumbens and lateral septum. …”
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Target-specific control of olfactory bulb periglomerular cells by GABAergic and cholinergic basal forebrain inputs by Didier De Saint Jan

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Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come by John J. Alam, Ralph A. Nixon

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Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin. by Christina Krabbe, Sara Thornby Bak, Pia Jensen, Christian von Linstow, Alberto Martínez Serrano, Claus Hansen, Morten Meyer

“…Regardless of oxygen levels, the content of TH-ir cells with mature neuronal morphologies was higher for midbrain as compared to forebrain cultures. Proliferative Ki67-ir cells were found in both types of cultures, but the relative proportion of these cells was significantly higher for forebrain NSCs cultured at low, as compared to high, oxygen tension. …”
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The behavioral signature of stepwise learning strategy in male rats and its neural correlate in the basal forebrain by Hachi E. Manzur, Ksenia Vlasov, You-Jhe Jhong, Hung-Yen Chen, Shih-Chieh Lin

“…At the neuronal level, this stepwise learning process was mirrored by the sequential emergence of basal forebrain neuronal responses toward each event, which quantitatively conveyed a reward prediction error signal and promoted reward-seeking behaviors. …”
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Relationship between the anterior forebrain mesocircuit and the default mode network in the structural bases of disorders of consciousness by Nicholas D. Lant, Laura E. Gonzalez-Lara, Adrian M. Owen, Davinia Fernández-Espejo

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Activation of basal forebrain-to-lateral habenula circuitry drives reflexive aversion and suppresses feeding behavior by Jessica L. Swanson, Joshua Ortiz-Guzman, Snigdha Srivastava, Pey-Shyuan Chin, Sean W. Dooling, Elizabeth Hanson Moss, Mikhail Y. Kochukov, Patrick J. Hunt, Jay M. Patel, Brandon T. Pekarek, Qingchun Tong, Benjamin R. Arenkiel

“…Here, we describe a basal forebrain (BF)-to-lateral habenula (LHb) circuit that directly modulates non-homeostatic feeding behavior. …”
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Microfluidic Cultures of Basal Forebrain Cholinergic Neurons for Assessing Retrograde Cell Death by Live Imaging by Srestha Dasgupta, Mansi Pandya, Wilma Friedman

“…In the brain, basal forebrain cholinergic neurons (BFCNs) possess extensive axons that project to several target regions such as the cortex, hippocampus, and amygdala, and may be exposed to a specific microenvironment in their axon targets that may have retrograde effects on neuronal health. …”
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Forebrain E-I balance controlled in cognition through coordinated inhibition and inhibitory transcriptome mechanism by Tian Tian, You Cai, You Cai, Xin Qin, Jiangang Wang, Yali Wang, Xin Yang

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Transcriptional Profiling of Ligand Expression in Cell Specific Populations of the Adult Mouse Forebrain That Regulates Neurogenesis by Kasum Azim, Rainer Akkermann, Martina Cantone, Julio Vera, Janusz J. Jadasz, Patrick Küry

“…In the adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the largest and most active source of neural stem cells (NSCs) that generates mainly neurons and few glial cells lifelong. …”
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Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients? by J. C. Soares

“…At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebrain bundle (MFB). Our preliminary results suggest effects in alleviating depressive symptoms in this very severe, refractory patient group. …”
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Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons. by Yuriko Iwakura, Ran Wang, Naoko Inamura, Kazuaki Araki, Shigeki Higashiyama, Nobuyuki Takei, Hiroyuki Nawa

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Increased basal forebrain volumes could prevent cognitive decline in LRRK2 Parkinson's disease by Lucia Batzu, Daniele Urso, Michel J. Grothe, Dániel Veréb, K. Ray Chaudhuri, Joana B. Pereira

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Forebrain Organoids to Model the Cell Biology of Basal Radial Glia in Neurodevelopmental Disorders and Brain Evolution by Flaminia Kaluthantrige Don, Nereo Kalebic

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Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration by William Sealy Hambright, Rene Solano Fonseca, Liuji Chen, Ren Na, Qitao Ran

“…To this end, we generated Gpx4BIKO mouse, a mouse model with conditional deletion in forebrain neurons of glutathione peroxidase 4 (Gpx4), a key regulator of ferroptosis, and showed that treatment with tamoxifen led to deletion of Gpx4 primarily in forebrain neurons of adult Gpx4BIKO mice. …”
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