Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5 by Barnes, MJ

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis by Seher Yuksel, Bogale Aredo, Yeshumenesh Zegeye, Cynthia X. Zhao, Miao Tang, Xiaohong Li, John D. Hulleman, Laurent Gautron, Sara Ludwig, Eva M. Y. Moresco, Igor A. Butovich, Bruce A. Beutler, Rafael L. Ufret-Vincenty

“…Here we use a semiquantitative fundus spot scoring scale in combination with an unbiased, state-of-the-science forward genetics pipeline to identify causative associations between chemically induced mutations and fundus spot phenotypes. …”
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A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene by Yonghe Ding, Di Lang, Jianhua Yan, Haisong Bu, Hongsong Li, Kunli Jiao, Jingchun Yang, Haibo Ni, Stefano Morotti, Tai Le, Karl J Clark, Jenna Port, Stephen C Ekker, Hung Cao, Yuji Zhang, Jun Wang, Eleonora Grandi, Zhiqiang Li, Yongyong Shi, Yigang Li, Alexey V Glukhov, Xiaolei Xu

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Research advance on cold tolerance in chrysanthemum by Qingbing Chen, Qingbing Chen, Kang Gao, YuRan Xu, YaHui Sun, YaHui Sun, Bo Pan, Bo Pan, Dongliang Chen, Chang Luo, Xi Cheng, Hua Liu, Conglin Huang

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Forward genetic screening identifies novel roles for N-terminal acetyltransferase C and histone deacetylase in C. elegans development by Rose Aria Malinow, Ming Zhu, Yishi Jin, Kyung Won Kim

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Next Generation Sequencing Based Forward Genetic Approaches for Identification and Mapping of Causal Mutations in Crop Plants: A Comprehensive Review by Parmeshwar K. Sahu, Richa Sao, Suvendu Mondal, Gautam Vishwakarma, Sudhir Kumar Gupta, Vinay Kumar, Sudhir Singh, Deepak Sharma, Bikram K. Das

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Two forward genetic screens for vein density mutants in sorghum converge on a cytochrome P450 gene in the brassinosteroid pathway. by Rizal, G, Thakur, V, Dionora, J, Karki, S, Wanchana, S, Acebron, K, Larazo, N, Garcia, R, Mabilangan, A, Montecillo, F, Danila, F, Mogul, R, Pablico, P, Leung, H, Langdale, J, Sheehy, J, Kelly, S, Quick, W

Advantages, disadvantages and research progress on strategies for screening and identifying functional genes by LIU Xu, CHANG De, WANG Jun-feng

Subjects: “…functional genes|forward genetics|reverse genetics|bioinformatics|model organism…”
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Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis. by Brea K Hampton, Kenneth S Plante, Alan C Whitmore, Colton L Linnertz, Emily A Madden, Kelsey E Noll, Samuel P Boyson, Breantie Parotti, James G Xenakis, Timothy A Bell, Pablo Hock, Ginger D Shaw, Fernando Pardo-Manuel de Villena, Martin T Ferris, Mark T Heise

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A high-throughput forward genetic screen identifies genes required for virulence of Pseudomonas syringae pv. maculicola ES4326 on Arabidopsis. by Karl J Schreiber, David Ye, Eric Fich, Allen Jian, Timothy Lo, Darrell Desveaux

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The Arabidopsis T‐DNA mutant SALK_008491 carries a 14‐kb deletion on chromosome 3 that provides rare insights into the plant response to dynamic light stress by Laura S. Lopez, Carsten Völkner, Philip M. Day, Chance M. Lewis, Chase L. Lewis, Dominik Schneider, Viviana Correa Galvis, Jeffrey A. Cruz, Ute Armbruster, David M. Kramer, Hans‐Henning Kunz

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Forward genetic studies reveal LsAPRR2 as a key gene in regulating the green color of pericarp in bottle gourd (Lagenaria siceraria) by Yulai Huo, Gui Zhang, Wenjin Yu, Zhengguo Liu, Mujie Shen, Rongchong Zhao, Shengping Hu, Xuyang Zheng, Peng Wang, Yanjuan Yang

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Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER–plasma membrane contact sites in Arabidopsis thaliana by Jennette M Codjoe, Ryan A Richardson, Fionn McLoughlin, Richard David Vierstra, Elizabeth S Haswell

“…To uncover signaling partners of MSL10, we employed a proteomic screen and a forward genetic screen; both unexpectedly implicated endoplasmic reticulum–plasma membrane contact sites (EPCSs) in MSL10 function. …”
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E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration by Yeshumenesh Zegeye, Bogale Aredo, Seher Yuksel, Dogan Can Kirman, Ashwani Kumar, Bo Chen, Emily Turpin, Sangita Shresta, Yu-Guang He, Laurent Gautron, Miao Tang, Xiaohong Li, Sophia M. DiCesare, John D. Hulleman, Chao Xing, Sara Ludwig, Eva Marie Y. Moresco, Bruce A. Beutler, Rafael L. Ufret-Vincenty

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Spectrum and Density of Gamma and X-ray Induced Mutations in a Non-Model Rice Cultivar by Joanna Jankowicz-Cieslak, Bernhard J. Hofinger, Luka Jarc, Sini Junttila, Bence Galik, Attila Gyenesei, Ivan L. Ingelbrecht, Bradley J. Till

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Screening for Stress Resistance Mutations in the Mouse by Wallace S Chick, Michael eLudwig, Xiaoyun eZhao, David eKitzenberg, Kristina eWilliams, Thomas E Johnson

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Membrane fluidity is regulated by the C. elegans transmembrane protein FLD-1 and its human homologs TLCD1/2 by Mario Ruiz, Rakesh Bodhicharla, Emma Svensk, Ranjan Devkota, Kiran Busayavalasa, Henrik Palmgren, Marcus Ståhlman, Jan Boren, Marc Pilon

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Two Novel Dimorphism-Related Virulence Factors of <i>Zymoseptoria tritici</i> Identified Using <i>Agrobacterium</i>-Mediated Insertional Mutagenesis by Alexander Yemelin, Annamaria Brauchler, Stefan Jacob, Andrew J. Foster, Julian Laufer, Larissa Heck, Luis Antelo, Karsten Andresen, Eckhard Thines

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Versatile mapping-by-sequencing with Easymap v.2 by Samuel Daniel Lup, Carla Navarro-Quiles, José Luis Micol

Subjects: “…forward genetics…”
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A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways by Campino, S, Marin-Menendez, A, Kemp, A, Cross, N, Drought, L, Otto, T, Benavente, E, Ravenhall, M, Schwach, F, Girling, G, Manske, M, Theron, M, Gould, K, Drury, E, Clark, T, Kwiatkowski, D, Pance, A, Rayner, J

“…Reverse genetic analysis of laboratory adapted strains has identified multiple genes that when deleted can alter invasion, but how the relative contributions of each gene translate to the phenotypes of clinical isolates is far from clear. We used a forward genetic approach to identify genes responsible for variable erythrocyte invasion by phenotyping the parents and progeny of previously generated experimental genetic crosses. …”