Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia av Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev

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Nutrient sensing and cAMP signaling in yeast: G-protein coupled receptor versus transceptor activation of PKA av Griet Van Zeebroeck, Liesbeth Demuyser, Zhiqiang Zhang, Ines Cottignie, Johan M. Thevelein

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Anatomic survey of seeding in Alzheimer’s disease brains reveals unexpected patterns av Barbara E. Stopschinski, Kelly Del Tredici, Sandi-Jo Estill-Terpack, Estifanos Ghebremedhin, Fang F. Yu, Heiko Braak, Marc I. Diamond

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Tau seeding in cases of multiple sclerosis av Michael S. LaCroix, Hilda Mirbaha, Ping Shang, Stephanie Zandee, Chan Foong, Alexandre Prat, Charles L. White, Olaf Stuve, Marc I. Diamond

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Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway av Taryn E Gillies, Michael Pargett, Jillian M Silva, Carolyn K Teragawa, Frank McCormick, John G Albeck

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Frequency modulation of ERK activation dynamics rewires cell fate av Hyunryul Ryu, Minhwan Chung, Maciej Dobrzyński, Dirk Fey, Yannick Blum, Sung Sik Lee, Matthias Peter, Boris N Kholodenko, Noo Li Jeon, Olivier Pertz

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A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells av Mei CQ Houser, Steven S Hou, Florian Perrin, Yuliia Turchyna, Brian J Bacskai, Oksana Berezovska, Masato Maesako

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Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs av Tae-Jin Kim, Chirlmin Joo, Jihye Seong, Reza Vafabakhsh, Elliot L Botvinick, Michael W Berns, Amy E Palmer, Ning Wang, Taekjip Ha, Eric Jakobsson, Jie Sun, Yingxiao Wang

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PLK1 Activation in Late G2 Sets Up Commitment to Mitosis av Lilia Gheghiani, Damarys Loew, Bérangère Lombard, Jörg Mansfeld, Olivier Gavet

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Characterization of PDGF-Induced Subcellular Calcium Regulation through Calcium Channels in Airway Smooth Muscle Cells by FRET Biosensors av Mingxing Ouyang, Binqian Zhou, Chunmei Li, Linhong Deng

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Single-Cell Biochemical Multiplexing by Multidimensional Phasor Demixing and Spectral Fluorescence Lifetime Imaging Microscopy av Kalina T. Haas, Kalina T. Haas, Maximilian W. Fries, Ashok R. Venkitaraman, Alessandro Esposito

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Correcting Artifacts in Ratiometric Biosensor Imaging; an Improved Approach for Dividing Noisy Signals av Daniel J. Marston, Scott D. Slattery, Klaus M. Hahn, Klaus M. Hahn, Denis Tsygankov

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