<i>Cachrys</i> L. Genus: A Comprehensive Review on Botany, Phytochemistry and Biological Properties by Vincenzo Musolino, Maria Rosaria Perri, Filomena Conforti, Micaela Gliozzi, Mariangela Marrelli, Vincenzo Mollace

“…These works mostly focused on the essential oils obtained from these plants, and pointed out that <i>Cachrys</i> species are a rich source of coumarins, mainly furanocoumarins. Other phytochemicals, such as terpenes, fatty acids, phytosterols, and flavonoids have been also identified. …”
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Role of Photoactive Phytocompounds in Photodynamic Therapy of Cancer by Kasipandi Muniyandi, Blassan George, Thangaraj Parimelazhagan, Heidi Abrahamse

“…This review focusses on the importance of common photoactive groups (furanocoumarins, polyacetylenes, thiophenes, curcumins, alkaloids, and anthraquinones), their phototoxic effects, anticancer activity and use as a potent PS for an effective PDT outcome in the treatment of various cancers.…”
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Insights into Antiviral Properties and Molecular Mechanisms of Non-Flavonoid Polyphenols against Human Herpesviruses by Sherif T. S. Hassan, Miroslava Šudomová, Alena Mazurakova, Peter Kubatka

“…Hence, in this article, we comprehensively summarize the recent advances that have been attained in employing plant non-flavonoid polyphenols, such as phenolic acids, tannins and their derivatives, stilbenes and their derivatives, lignans, neolignans, xanthones, anthraquinones and their derivatives, curcuminoids, coumarins, furanocoumarins, and other polyphenols (phloroglucinol) as promising anti-herpesvirus drugs against various types of herpesvirus such as alpha-herpesviruses (herpes simplex virus type 1 and 2 and varicella-zoster virus), beta-herpesviruses (human cytomegalovirus), and gamma-herpesviruses (Epstein–Barr virus and Kaposi sarcoma-associated herpesvirus). …”
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The traditional uses, pharmacology, and phytochemistry of Peucedanum praeruptorum Dunn by Qiongxiao Wang, Qingmei Sun, Qinger Huang, Luping Qin, Bo Zhu

“…P. praeruptorum was found to contain more than 119 distinct phytochemicals, including simple coumarins, pyranocoumarins, furanocoumarins, flavonoids, ketones, organic acids, and sterols, among others (e.g., praeruptorins A and B). …”
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Hogweed Seed Oil: Physico–Chemical Characterization, LC-MS Profile, and Neuroprotective Activity of <i>Heracleum dissectum</i> Nanosuspension by Daniil N. Olennikov, Nadezhda K. Chirikova

“…High-performance liquid chromatography with photodiode array detection and electrospray ionization triple quadrupole mass spectrometric detection (HPLC–PDA–ESI–tQ–MS/MS) identified 38 coumarins that were characterized and quantified. Various furanocoumarins were the major components of HSO polyphenolics, including imperatorin, phellopterin, and isoimperatorin, and the total coumarin content in HSO varied from 181.14 to 238.42 mg/mL. …”
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Safety of ashitaba sap as a Novel food pursuant to Regulation (EU) 2015/2283 by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Miguel Prieto Maradona, Monika Neuhäuser‐Berthold, Morten Poulsen, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Maria Glymenaki, Eirini Kouloura, Helle Katrine Knutsen

“…The principal constituents of the sap with regard to the safety assessment are chalcones (1%–2.25%) and furanocoumarins (< 0.01%). The applicant proposed to use the NF in food supplements at a maximum dose of 780 mg per day. …”
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STUDY OF THE CHEMICAL COMPOSITION OF THE ESSENTIAL OIL RECEIVED FROM HERBAL DRUG PRODUCTS OF SHIZANDRA CHINESIS’ SEEDS (<i>SCHISÁNDRA CHINÉNSIS </i>BAILL.) BY THE CHROMATOMASS-SPEC... by N. V. Kartashova, I. A. Samylina, A. V. Strelyaeva, R. M. Kuznetsov

“…The following groups of biologically active substances were found in the essential oil from the Shizandra сhinesis' seeds: terpenoids, phenylpropanoids, triterpene saponins, glycosides, carbohydrates, lignans, amino acids and furanocoumarins.…”
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Characterization of the endophytic bacterial community of Bituminaria bituminosa plant grown in vitro and its interaction with the plant extract by Carolina Chiellini, Marinella De Leo, Marinella De Leo, Vincenzo Longo, Ylenia Pieracci, Laura Pistelli, Laura Pistelli

“…IntroductionBituminaria bituminosa is a medicinal plant recognized for its phytochemicals, such as furanocoumarins, pterocarpans, and flavonoids. Since the secondary metabolism is influenced by the plant-endophyte interactions, the endophytic bacterial community of B. bituminosa was explored and the possible interactions with the plant were described.Materials and methodsDifferent bacterial strains were isolated from different organs of in vitro plants as shoots, roots, and seeds. …”
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Biological importance of bioactive phytochemical ‘Cimifugin’ as potential active pharmaceutical ingredients against human disorders: A natural phytochemical for new therapeutic alt... by Dinesh Kumar Patel

“…The biological importance of furanocoumarins and coumarins has also been discussed in the present work in order to understand the biological importance of cimifugin. …”
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Methoxyfuranocoumarins of Natural Origin–Updating Biological Activity Research and Searching for New Directions—A Review by Magdalena Bartnik

“…Plant secondary metabolites, including furanocoumarins, have attracted attention for decades as active molecules with therapeutic potential, especially those occurring in a limited number of species as evolutionarily specific and chemotaxonomically important. …”
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Studies on the Accumulation of Secondary Metabolites and Evaluation of Biological Activity of In Vitro Cultures of <i>Ruta montana</i> L. in Temporary Immersion Bioreactors by Agnieszka Szewczyk, Andreana Marino, Maria Fernanda Taviano, Lucia Cambria, Federica Davì, Monika Trepa, Mariusz Grabowski, Natalizia Miceli

“…High-performance liquid chromatography analysis was performed to characterize furanocoumarins, furoquinoline alkaloids, phenolic acids, and catechins. …”
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The Effect of Hydroalcoholic Extract of Dorema Aucheri on CD40 Protein Expression in Thoracic Aorta of Male White Rabbits Fed with Hypercholesterolemic Diet by Gholam Reza Dashti, Ahmad Teimourinejad, Mansour Salehi, Seyyed Ebrahim Sajadi, Nakisa Torabinia

“…This property might be due to the presence of flavonoids, antioxidants and other compounds such as furanocoumarins that have been identified in the plant extract.…”
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An Overview of Potential Natural Photosensitizers in Cancer Photodynamic Therapy by Bushra Aziz, Iffat Aziz, Ahmat Khurshid, Ehsan Raoufi, Fahime Nasr Esfahani, Zahra Jalilian, M. R. Mozafari, Elham Taghavi, Masroor Ikram

“…In this review, we highlight the current research regarding several photoactive phytocompound classes (furanocoumarins, alkaloids, poly-acetylenes and thiophenes, curcumins, flavonoids, anthraquinones, and natural extracts) and their photoactive potential to encourage researchers to focus on studies of natural agents and their use as a potent PS to enhance the efficiency of PDT.…”
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<i>Ducrosia</i> spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review by Javad Mottaghipisheh, Anahita Boveiri Dehsheikh, Mohammad Mahmoodi Sourestani, Tivadar Kiss, Judit Hohmann, Dezső Csupor

“…Among the 49 non-volatile secondary metabolites identified from <i>D. anethifolia</i> and <i>D. ismaelis</i>, 17 linear furanocoumarins and 8 flavonoids have been characterized. …”
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Analysis of Characteristic Ion Reactions and Mechanism Exploration of Active Ingredients in Traditional Chinese Medicine by Direct Analysis in Real-Time Mass Spectrometry by LIU Xin1;HOU Yu-zhu1;YANG Tong-tong1;LI Na1;LIU Shu-ying1;ZHANG Zhe1;SU Rui

“…The oxidation mechanisms of furanocoumarins and the dehydrogenation mechanisms of dihydroflavonoids were deduced according to the tandem mass spectrometry of the characteristic ion products and the proposed fragmentation pathways. …”
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A Biochemometric Approach for the Identification of In Vitro Anti-Inflammatory Constituents in Masterwort by Julia Zwirchmayr, Ulrike Grienke, Scarlet Hummelbrunner, Jacqueline Seigner, Rainer de Martin, Verena M. Dirsch, Judith M. Rollinger

“…In this way, four furanocoumarins (imperatorin, ostruthol, saxalin, and 2’-O-acetyloxypeucedanin), one coumarin (ostruthin), and one chromone (peucenin) were identified as NF-κB inhibiting constituents of PO-E contributing to the observed NF-ĸB inhibitory activity. …”
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Pomelo juice–Drug interactions: A word of caution by Greeshma V Shetty, P N Girish, K P Gopalakrishna Rao, Ashok Menon

“…Pomelo is closely related to grapefruit and extensively studied and contains furanocoumarins which have been identified as inhibitors of cytochrome P450 3A4 in grapefruit juice in vitro. …”
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Preparation, Characterization, and Pharmacokinetic Evaluation of Imperatorin Lipid Microspheres and Their Effect on the Proliferation of MDA-MB-231 Cells by Xinli Liang, Xulong Chen, Guowei Zhao, Tao Tang, Wei Dong, Chunyan Wang, Jing Zhang, Zhenggen Liao

“…Imperatorin is a chemical compound belonging to the linear furanocoumarins. Imperatorin is attracting considerable attention because of its antitumor, antibacterial, anti-inflammatory, and anticoagulant activities, inhibition of myocardial hypertrophy, and other pharmacological efficacies. …”
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