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2841
The effect of the alpha-specific PI3K inhibitor alpelisib combined with anti-HER2 therapy in HER2+/PIK3CA mutant breast cancer
Published 2023-07-01“…Here, we investigated the in vitro and in vivo antitumor efficacy of the alpha-specific PI3K inhibitor alpelisib alone or in combination with anti-HER2 therapy using a panel of HER2+ BC cell lines. We also generated models of acquired resistance to alpelisib to investigate the mechanisms underlying resistance to alpha-specific PI3K inhibition.Materials and methodsPIK3CA mutant (HCC1954, KPL4 and JMT1) and wild-type (BT474 and SKBR3) HER2+ BC cell lines were used. …”
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2842
Advanced topics in weakly supervised learning
Published 2021“…We propose the first generation model of partially labeled data, and develop two novel partial-label learning methods that are guaranteed to be provably consistent, i.e., one is risk-consistent and the other is classifier-consistent. …”
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Thesis-Doctor of Philosophy -
2843
Towards humanized open-domain conversational agents
Published 2021“…We then incorporate commonsense into emotional CAs and propose a conversational emotion recognition model and a commonsense-aware emotional response generation model. Experimental results show that both emotion and commonsense improve response quality and human ratings. …”
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Thesis-Doctor of Philosophy -
2844
Context-aware mobile image recognition and annotation
Published 2013“…For mobile image recognition, we proposed several approaches based on content analysis with possible incorporation of context information: 1) A new approach for scene image recognition is proposed by combining generative models and discriminative models. A new image signature is proposed based on Gaussian Mixture Model (GMM), and its soft relevance value is incorporated into training of Fuzzy Support Vector Machine (FSVM). …”
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Thesis -
2845
Bridging images and natural language with deep learning
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Thesis -
2846
Three essays in inequality and health economics
Published 2019“…In the third essay, we build an overlapping generation model to examine the reason why developed countries with similar background have implemented different social health insurance systems. …”
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Thesis -
2847
Flexible estimation of temporal point processes and graphs
Published 2023“…Graphs are typical examples of non-Euclidean data, where adequate distance measures, similarity functions, and generative models need to be formalised. In the deep learning community, graphs have become particularly popular within the field of <i>geometric deep learning</i>.…”
Thesis -
2848
Scalable Bayesian regression utilising marginal information
Published 2017“…The model introduced in Chapter 3 is applied in the context of subgroup analysis, providing a Bayesian nonparametric analogue to this approach: where inference is based only on the order of the data, circumventing the requirement to specify a full data-generating model. Both approaches to subgroup analysis are applied to data from an AIDS Clinical Trial.…”
Thesis -
2849
Integration of object-based image analysis and data mining techniques for detailes urban mapping using remote sensing
Published 2015“…The rulebased classification of the first study site obtained an overall accuracy of 87.90%. Finally, the generated model was validated in the second study site to prove that its performance was reproducible and applicable to an area with a wider geographic coverage. …”
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Thesis -
2850
Estimation of ground level PM₂.₅ concentration using aerosol optical thickness from modis images in Peninsular Malaysia
Published 2019“…Subsequently, a comparison of strengths and weaknesses was held between the various generated models. Lastly, an assessment of the accuracy of PM2.5 estimation has been conducted on the MODIS spatial models. …”
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Thesis -
2851
The Regional Aerosol Model Intercomparison Project (RAMIP)
Published 2023-08-01“…All experiments are based on the shared socioeconomic pathways and are intended to be performed with 6th Climate Model Intercomparison Project (CMIP6) generation models, initialised from the CMIP6 historical experiments, to facilitate comparisons with existing projections. …”
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Article -
2852
An Innovative Telemedical Network to Improve Infectious Disease Management in Critically Ill Patients and Outpatients (TELnet@NRW): Stepped-Wedge Cluster Randomized Controlled Tria...
Published 2022-03-01“…For the other recommendations, we found no significant effects, or we had too few observations to generate models. The key limitations of our study include selection effects due to the applied on-site triage of patients as well as the limited possibilities to control for secular effects. …”
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2853
The Phase Transition Analysis for the Random Regular Exact 2-(<i>d</i>, <i>k</i>)-SAT Problem
Published 2021-07-01“…This paper introduces the (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>d</mi><mo>,</mo><mi>k</mi></mrow></semantics></math></inline-formula>)-SAT instance generation model, constructs the solution space, and employs the method of the first and second moments to present the phase transition point <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>d</mi><mo>*</mo></msup></semantics></math></inline-formula> of the 2-(<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>d</mi><mo>,</mo><mi>k</mi></mrow></semantics></math></inline-formula>)-SAT instance with only positive literals. …”
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2854
Scale-Free Random SAT Instances
Published 2022-06-01“…We provide a different generation model of SAT instances, called <i>scale-free random SAT instances.…”
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2855
Chemistry, Transport and Function of Ionic Phases in the Solid Electrolyte Interphase on Lithium Metal Anodes
Published 2023“…In the first part of this thesis, single-component SEI of lithium oxide (Li2O) was synthesized directly onto Li foils by controlled metal-gas reactions, generating model Li2O SEI with nanoscale thicknesses (20–100 nm) commensurate with the native SEI derived from electrolytes. …”
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Thesis -
2856
From foreign aid to domestic debt: essays on government financing in developing economies
Published 2014“…We employ an overlapping generations model featuring credit constraints to study the real effects of such free lunch expectations in a small open economy, drawing contrasts with the standard tax and money finance closure rules. …”
Thesis -
2857
Disinfection of rice using ozone treatment
Published 2009“…The glass condenser was connected to an ozone generator (Model OM-1, Top Ozone,Malaysia) in which ozone was produced from the ambient air. …”
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Thesis -
2858
Architecture and algorithm development for generative adversarial networks
Published 2020“…Generative Adversarial Networks (GANs) are recently invented generative models which can produce highly realistic samples such as images. …”
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Thesis-Doctor of Philosophy -
2859
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2860