Showing 21 - 40 results of 361,384 for search '"genes"', query time: 0.81s Refine Results
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    Gene-gene interactions in breast cancer susceptibility by Turnbull, C, Seal, S, Renwick, A, Warren-perry, M, Hughes, D, Elliott, A, Pernet, D, Peock, S, Adlard, J, Barwell, J, Berg, J, Brady, A, Brewer, C, Brice, G, Chapman, C, Cook, J, Davidson, R, Donaldson, A, Douglas, F, Greenhalgh, L, Henderson, A, Izatt, L, Kumar, A, Lalloo, F, Miedzybrodzka, Z

    Published 2012
    “…There have been few definitive examples of gene-gene interactions in humans. Through mutational analyses in 7325 individuals, we report four interactions (defined as departures from a multiplicative model) between mutations in the breast cancer susceptibility genes ATM and CHEK2 with BRCA1 and BRCA2 (case-only interaction between ATM and BRCA1/BRCA2 combined, P = 5.9 × 10 -4; ATM and BRCA1, P= 0.01; ATM and BRCA2, P= 0.02; CHEK2 and BRCA1/BRCA2 combined, P = 2.1 × 10 =4; CHEK2 and BRCA1, P= 0.01; CHEK2 and BRCA2, P= 0.01). …”
    Journal article
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    Gene-gene interactions in breast cancer susceptibility. by Turnbull, C, Seal, S, Renwick, A, Warren-Perry, M, Hughes, D, Elliott, A, Pernet, D, Peock, S, Adlard, J, Barwell, J, Berg, J, Brady, A, Brewer, C, Brice, G, Chapman, C, Cook, J, Davidson, R, Donaldson, A, Douglas, F, Greenhalgh, L, Henderson, A, Izatt, L, Kumar, A, Lalloo, F, Miedzybrodzka, Z

    Published 2012
    “…There have been few definitive examples of gene-gene interactions in humans. Through mutational analyses in 7325 individuals, we report four interactions (defined as departures from a multiplicative model) between mutations in the breast cancer susceptibility genes ATM and CHEK2 with BRCA1 and BRCA2 (case-only interaction between ATM and BRCA1/BRCA2 combined, P = 5.9 × 10(-4); ATM and BRCA1, P= 0.01; ATM and BRCA2, P= 0.02; CHEK2 and BRCA1/BRCA2 combined, P = 2.1 × 10(-4); CHEK2 and BRCA1, P= 0.01; CHEK2 and BRCA2, P= 0.01). …”
    Journal article
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    Programmed gene rearrangements altering gene expression. by Borst, P, Greaves, D

    Published 1987
    “…Programmed gene rearrangements are used in nature to to alter gene copy number (gene amplification and deletion), to create diversity by reassorting gene segments (as in the formation of mammalian immunoglobulin genes), or to control the expression of a set of genes that code for the same function (such as surface antigens). …”
    Journal article
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    Perinatal Gene-Gene and Gene-Environment Interactions on IgE Production and Asthma Development by Jen-Chieh Chang, Lin Wang, Rong-Fu Chen, Chieh-An Liu

    Published 2012-01-01
    “…This paper reviews and summarizes how gene-gene and gene-environment interactions affect IgE production and the development of atopic asthma in prenatal and childhood stages. …”
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    Article
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    Genes VIII / by 441264 Lewin, Benjamin

    Published 2004
    Subjects:
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    Powerful Tukey's One Degree-of-Freedom Test for Detecting Gene-Gene and Gene-Environment Interactions by Yaping Wang, Donghui Li, Peng Wei

    Published 2015-01-01
    “…This “missing heritability” problem has been partly attributed to the yet-to-be-identified gene-gene (G × G) and gene-environment (G × E) interactions. …”
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    Article
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    Association, Haplotype, and Gene-Gene Interactions of the HPA Axis Genes with Suicidal Behaviour in Affective Disorders by Anna Leszczyńska-Rodziewicz, Aleksandra Szczepankiewicz, Joanna Pawlak, Monika Dmitrzak-Weglarz, Joanna Hauser

    Published 2013-01-01
    “…Therefore, we found it interesting to study polymorphisms of genes involved in the HPA axis (CRHR1, NR3C1, and AVPBR1). …”
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    Article
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    The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex. by Nylenna, O, Naper, C, Vaage, J, Woon, P, Gauguier, D, Dissen, E, Ryan, J, Fossum, S

    Published 2005
    “…We here report the cDNA sequences of 11 new rat Ly49 genes with full and three with incomplete open reading frames. …”
    Journal article