Novel lentiviral vectors for gene therapy of sickle cell disease combining gene addition and gene silencing strategies by Mégane Brusson, Anne Chalumeau, Pierre Martinucci, Oriana Romano, Tristan Felix, Valentina Poletti, Samantha Scaramuzza, Sophie Ramadier, Cecile Masson, Giuliana Ferrari, Fulvio Mavilio, Marina Cavazzana, Mario Amendola, Annarita Miccio

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Search for genes gained by horizontal gene transfer in an entomopoxvirus, with special reference to the analysis of the transfer of an ABC transporter gene by Takafumi N Sugimoto, Akiya Jouraku, Wataru Mitsuhashi

“…Although it is generally believed that large DNA viruses capture genes by horizontal gene transfer (HGT), the detailed manner of such transfer has not been fully elucidated. …”
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Comparative GO: a web application for comparative gene ontology and gene ontology-based gene selection in bacteria. by Mario Fruzangohar, Esmaeil Ebrahimie, Abiodun D Ogunniyi, Layla K Mahdi, James C Paton, David L Adelson

“…The primary means of classifying new functions for genes and proteins relies on Gene Ontology (GO), which defines genes/proteins using a controlled vocabulary in terms of their Molecular Function, Biological Process and Cellular Component. …”
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Gene-gene interactions and prevalence of gene polymorphism associated with disorders of hemostasis and folate metabolism in patients with recurrent miscarriage by Nataly I Frolova, Tatiana E Belokrinitskaya, Nataliya N Strambovskaya, Evgeniya P Belozertseva

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Selection of Fusarium Trichothecene Toxin Genes for Molecular Detection Depends on TRI Gene Cluster Organization and Gene Function by Ria T. Villafana, Amanda C. Ramdass, Sephra N. Rampersad

“…Due to the challenges of inducing trichothecene production by Fusarium isolates in vitro for subsequent chemical analysis, PCR assays using gene-specific primers, either singly or in combination, designed against specific genes of the trichothecene gene cluster of multiple species of Fusarium have been developed. …”
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The natural history of class I primate alcohol dehydrogenases includes gene duplication, gene loss, and gene conversion. by Matthew A Carrigan, Oleg Uryasev, Ross P Davis, Lanmin Zhai, Thomas D Hurley, Steven A Benner

“…Gene duplication is a source of molecular innovation throughout evolution. …”
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Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions. by Manuguerra, M, Matullo, G, Veglia, F, Autrup, H, Dunning, A, Garte, S, Gormally, E, Malaveille, C, Guarrera, S, Polidoro, S, Saletta, F, Peluso, M, Airoldi, L, Overvad, K, Raaschou-Nielsen, O, Clavel-Chapelon, F, Linseisen, J, Boeing, H, Trichopoulos, D, Kalandidi, A, Palli, D, Krogh, V, Tumino, R, Panico, S, Bueno-De-Mesquita, H

“…We applied the multi-factor dimensionality reduction (MDR) method to a large cohort study on gene-environment and gene-gene interactions. The study (case-control nested in the EPIC cohort) was established to investigate molecular changes and genetic susceptibility in relation to air pollution and environmental tobacco smoke (ETS) in non-smokers. …”

Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions by Manuguerra, M, Matullo, G, Veglia, F, Autrup, H, Dunning, A, Garte, S, Gormally, E, Malaveille, C, Guarrera, S, Polidoro, S, Saletta, F, Peluso, M, Airoldi, L, Overvad, K, Raaschou-Nielsen, O, Clavel-Chapelon, F, Linseisen, J, Boeing, H, Trichopoulos, D, Kalandidi, A, Palli, D, Krogh, V, Tumino, R, Panico, S, Bueno-De-Mesquita, H

“…We applied the multi-factor dimensionality reduction (MDR) method to a large cohort study on gene-environment and gene-gene interactions. The study (case-control nested in the EPIC cohort) was established to investigate molecular changes and genetic susceptibility in relation to air pollution and environmental tobacco smoke (ETS) in non-smokers. …”

Transcriptional Profiling of the Effect of <i>Coleus amboinicus</i> L. Essential Oil against <i>Salmonella</i> Typhimurium Biofilm Formation by Arpron Leesombun, Sivapong Sungpradit, Ladawan Sariya, Jarupha Taowan, Sookruetai Boonmasawai

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Evolutionary signatures amongst disease genes permit novel methods for gene prioritization and construction of informative gene-based networks. by Nolan Priedigkeit, Nicholas Wolfe, Nathan L Clark

“…Genes involved in the same function tend to have similar evolutionary histories, in that their rates of evolution covary over time. …”
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Differentially Expressed Genes in Atopic Dermatitis: Bioinformatics analysis of pooled microarray gene expression datasets in Gene Expression Omnibus by Danna Jia, Wenqiang Chen, Bin Li

“…Using bioinformatics methods, candidate genes and biological pathways involved in AD pathogenesis were identified based on gene expression profiles in the Gene Expression Omnibus (GEO) database. …”
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EHBP1, TUBB, and WWOX SNPs, Gene-Gene and Gene-Environment Interactions on Coronary Artery Disease and Ischemic Stroke by Chun-Xiao Liu, Rui-Xing Yin, Xiao-Li Cao, Zong-Hu Shi, Feng Huang, Bi-Liu Wei, Guo-Xiong Deng, Peng-Fei Zheng, Yao-Zong Guan

“…This study aimed to detect the associations of these SNPs, gene-gene and gene-environment interactions and CAD and IS in the Guangxi Han population. …”
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Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes by Carlos G. Urzúa-Traslaviña, Tijs van Lieshout, Floranne Boulogne, Kevin Domanegg, Mahmoud Zidan, Olivier B. Bakker, Annique Claringbould, Jeroen de Ridder, Wilbert Zwart, Harm-Jan Westra, Patrick Deelen, Lude Franke

Subjects: “…Cancer susceptibility genes…”
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A versatile site-directed gene trap strategy to manipulate gene activity and control gene expression in Caenorhabditis elegans. by Haania Khan, Xinyu Huang, Vishnu Raj, Han Wang

“…The ability to manipulate gene activity and control transgene expression is essential to study gene function. …”
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TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens by Muellner, M, Duernberger, G, Ganglberger, F, Kerzendorfer, C, Uras, I, Schoenegger, A, Bagienski, K, Colinge, J, Nijman, S

“… <p style="text-align:justify;"> <b>Background:</b> Measuring the impact of combinations of genetic or chemical perturbations on cellular fitness, sometimes referred to as synthetic lethal screening, is a powerful method for obtaining novel insights into gene function and drug action. Especially when performed at large scales, gene-gene or gene-drug interaction screens can reveal complex genetic interactions or drug mechanism of action or even identify novel therapeutics for the treatment of diseases.…”

Gene therapy protocols : production and in vivo applications of gene transfer vectors / by LeDoux, Joseph

Subjects: “…Gene therapy…”

GUS protocols : using the GUS gene as a reporter of gene expression / by Gallagher, Sean R.

Subjects: “…Beta-glucuronidase genes…”

Divergence of gene body DNA methylation and evolution of plant duplicate genes. by Jun Wang, Nicholas C Marowsky, Chuanzhu Fan

“…It has been shown that gene body DNA methylation is associated with gene expression. …”
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Construction of an Insertion Vector for Gene Targeting of Chicken Lens-specific Gene by Yuji Fukushima, Masaharu Sato, Haruo Matsuda, Shuichi Furusawa, Hiroyuki Horiuchi

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The IRX3 Gene; the Missing Link between the FTO Gene and Obesity by Saeid Doaei, Maryam Gholamalizadeh, Alireza Mousavi Jarrahi, Marjan Badakhanian, Rahim Najafi

Subjects: “…irx3 gene, the fto gene, obesity…”
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