A SLAF-based high-density genetic map construction and genetic architecture of thermotolerant traits in maize (Zea mays L.) by Tingting Wen, Tingting Wen, Xuefei Zhang, Jiaojiao Zhu, Susu Zhang, Mohammad Saidur Rhaman, Wei Zeng

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Construction of a high-density genetic map and dissection of genetic architecture of six agronomic traits in tobacco (Nicotiana tabacum L.) by Zhijun Tong, Manling Xu, Qixin Zhang, Feng Lin, Dunhuang Fang, Xuejun Chen, Tianneng Zhu, Yingchao Liu, Haiming Xu, Bingguang Xiao

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Large-Scale Whole Genome Sequencing Study Reveals Genetic Architecture and Key Variants for Breast Muscle Weight in Native Chickens by Xiaodong Tan, Lu Liu, Xiaojing Liu, Huanxian Cui, Ranran Liu, Guiping Zhao, Jie Wen

“…The Jingxing yellow chicken, including an original (without human-driven selection) line and a selected line (based on selection for increased intramuscular fat content), were used to dissect the genetic architecture and key variants associated with BrW. …”
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Investigating the shared genetic architecture between COVID-19 and obesity: a large-scale genome wide cross-trait analysis by Yanjing Chen, Chunhua Fan, Jun Liu, Jun Liu

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Genetic architecture of F2 and identified transgressive segregants for yield and its component traits in bread wheat (Triticum aestivum L.) by Parul Gupta1* , Ravindra Prasad1 and Mohit Sharma2

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The Genetic Architecture of the Root System during Seedling Emergence in <i>Populus euphratica</i> under Salt Stress and Control Environments by Zhou Liang, Huiying Gong, Kaiyan Lu, Xiaoyu Zhang

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Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds by Lingzhao Fang, Goutam Sahana, Peipei Ma, Guosheng Su, Ying Yu, Shengli Zhang, Mogens Sandø Lund, Peter Sørensen

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Genetic architecture of post-harvest tuber quality traits in bush yam (Dioscorea praehensilis Benth.) germplasm through association mapping by Adeyinka S. Adewumi, Adeyinka S. Adewumi, Paul A. Asare, Oluyemi Titilola Akintayo, Idris I. Adejumobi, Michael O. Adu, Kingsley J. Taah, Emmanuel Afutu, Vincent A. Opoku, Adekemi E. Stanley, Selorm Akaba, Jean M. Mondo, Hapson Mushoriwa, Paterne A. Agre

“…Limited information on the genetic architecture and its poor post-harvest tuber quality traits significantly hinder its use as food and source of income. …”
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Erratum: Integration of multiple-omics data to reveal the shared genetic architecture of educational attainment, intelligence, cognitive performance, and Alzheimer’s disease by Frontiers Production Office

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Identifying novel genetic loci associated with polycystic ovary syndrome based on its shared genetic architecture with type 2 diabetes by Xiaoyi Li, Han Xiao, Yujia Ma, Zechen Zhou, Dafang Chen

“…These findings provide a new understanding of the shared genetic architecture between PCOS and T2D and the underlying molecular genetic mechanism of PCOS.…”
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Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. by Felix Day, Tugce Karaderi, Michelle R Jones, Cindy Meun, Chunyan He, Alex Drong, Peter Kraft, Nan Lin, Hongyan Huang, Linda Broer, Reedik Magi, Richa Saxena, Triin Laisk, Margrit Urbanek, M Geoffrey Hayes, Gudmar Thorleifsson, Juan Fernandez-Tajes, Anubha Mahajan, Benjamin H Mullin, Bronwyn G A Stuckey, Timothy D Spector, Scott G Wilson, Mark O Goodarzi, Lea Davis, Barbara Obermayer-Pietsch, André G Uitterlinden, Verneri Anttila, Benjamin M Neale, Marjo-Riitta Jarvelin, Bart Fauser, Irina Kowalska, Jenny A Visser, Marianne Andersen, Ken Ong, Elisabet Stener-Victorin, David Ehrmann, Richard S Legro, Andres Salumets, Mark I McCarthy, Laure Morin-Papunen, Unnur Thorsteinsdottir, Kari Stefansson, 23andMe Research Team, Unnur Styrkarsdottir, John R B Perry, Andrea Dunaif, Joop Laven, Steve Franks, Cecilia M Lindgren, Corrine K Welt

“…Only one locus differed significantly in its association by diagnostic criteria; otherwise the genetic architecture was similar between PCOS diagnosed by self-report and PCOS diagnosed by NIH or non-NIH Rotterdam criteria across common variants at 13 loci. …”
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Dissecting the genetic architecture of leaf morphology traits in mungbean (Vigna radiata (L.) Wizcek) using genome‐wide association study by Kevin O. Chiteri, Shivani Chiranjeevi, Talukder Zaki Jubery, Ashlyn Rairdin, Somak Dutta, Baskar Ganapathysubramanian, Arti Singh

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Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility by Landi, MT, Bishop, DT, MacGregor, S, Hunter, D

“…These findings provide insights into cutaneous melanoma genetic architecture, reinforcing the importance of nevogenesis, pigmentation and telomere maintenance, together with identifying potential new pathways for cutaneous melanoma pathogenesis.…”

Novel method for combined linkage and genome-wide association analysis finds evidence of distinct genetic architecture for two subtypes of autism. by Vieland, V, Hallmayer, J, Huang, Y, Pagnamenta, A, Pinto, D, Khan, H, Monaco, A, Paterson, A, Scherer, S, Sutcliffe, J, Szatmari, P

“…Our analysis also allowed for potential differences in genetic architecture for ASD in the presence or absence of lower IQ, an important clinical indicator of ASD subtypes. …”

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. by Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Luan, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Völzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, van der Velde, N, Groot, LCPGMD, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, Heemst, DV, Kleber, ME, März, W, de Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaëlsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Broer, L, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimäki, T, Lyytikäinen, L-P, Kähönen, M, Raitakari, OT, Mikkilä, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hyppönen, E, Kraft, P, Kiel, DP

GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture by Stevelink, R, Campbell, C, Chen, S, Kariuki, S

“…Subtype analysis revealed markedly different genetic architectures between focal and generalized epilepsies. …”

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria by Day, F, Karaderi, T, Jones, MR, Meun, C, He, C, Drong, A, Kraft, P, Lin, N, Huang, H, Broer, L, Magi, R, Saxena, R, Laisk, T, Urbanek, M, Hayes, MG, Thorleifsson, G, Fernandez-Tajes, J, Mahajan, A, Mullin, BH, Stuckey, BGA, Spector, TD, Wilson, SG, Goodarzi, MO, Davis, L, Obermayer-Pietsch, B, Uitterlinden, AG, Anttila, V, Neale, BM, Jarvelin, M-R, Fauser, B, Kowalska, I, Visser, JA, Andersen, M, Ong, K, Stener-Victorin, E, Ehrmann, D, Legro, RS, Salumets, A, McCarthy, MI, Morin-Papunen, L, Thorsteinsdottir, U, Stefansson, K, 23Andme Research Team, Styrkarsdottir, U, Perry, JRB, Dunaif, A, Laven, J, Franks, S, Lindgren, CM, Welt, CK

“…Only one locus differed significantly in its association by diagnostic criteria; otherwise the genetic architecture was similar between PCOS diagnosed by self-report and PCOS diagnosed by NIH or non-NIH Rotterdam criteria across common variants at 13 loci. …”

Novel method for combined linkage and genome-wide association analysis finds evidence of distinct genetic architecture for two subtypes of autism by Vieland, V, Hallmayer, J, Huang, Y, Pagnamenta, A, Pinto, D, Khan, H, Monaco, A, Paterson, A, Scherer, S, Sutcliffe, J, Szatmari, P

“…Our analysis also allowed for potential differences in genetic architecture for ASD in the presence or absence of lower IQ, an important clinical indicator of ASD subtypes. …”

The genetic architecture of socially-affected traits: a GWAS for direct and indirect genetic effects on survival time in laying hens showing cannibalism by Tessa Brinker, Piter Bijma, Addie Vereijken, Esther D. Ellen

“…Conclusions This is one of the first large studies investigating the genetic architecture of a socially-affected trait. The power to detect SNP associations was relatively low and thus we expect that many effects on DGE and IGE remained undetected. …”
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Underlying genetic architecture of resistance to mastitis in dairy cattle: A systematic review and gene prioritization analysis of genome-wide association studies by Saranya G. Narayana, Ellen de Jong, Flavio S. Schenkel, Pablo A.S. Fonseca, Tatiane C.S. Chud, Diana Powell, Garrett Wachoski-Dark, Paul E. Ronksley, Filippo Miglior, Karin Orsel, Herman W. Barkema

“…Genome-wide association studies have been widely used to identify genomic variants associated with complex traits, including resistance to mastitis, to elucidate the underlying genetic architecture of the trait. However, no systematic review and gene prioritization analysis have been conducted to date on GWAS results for resistance to mastitis in dairy cattle. …”
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