Developing a genetic engineering method for Acetobacterium wieringae to expand one-carbon valorization pathways by João P. C. Moreira, John T. Heap, Joana I. Alves, Lucília Domingues

“…The species A. wieringae has not been genetically modified, therefore developing a genetic engineering method is important for expanding its product portfolio from gas fermentation and overall improving the characteristics of this acetogen for industrial demands. …”
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Brain-Wide Transgene Expression in Mice by Systemic Injection of Genetically Engineered Exosomes: CAP-Exosomes by Saumyendra N. Sarkar, Deborah Corbin, James W. Simpkins

“…In this manuscript, we describe, for the first time, the development of a workflow to generate a novel brain-targeted drug delivery system that involves the generation of genetically engineered exosomes by first selecting various functional AAV capsid-specific peptides (collectively called CAPs) known to be involved in brain-targeted high-expression gene delivery, and then expressing the CAPs in frame with lysosome-associated membrane glycoprotein (Lamp2b) followed by expressing CAP-Lamp2b fusion protein on the surface of mesenchymal stem cell-derived exosomes, thus generating CAP-exosomes. …”
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Construction of Eicosatetraenoic Acid Producing Cell Factory by Genetic Engineering of <i>Mucor circinelloides</i> by Chen Wu, Junhuan Yang, Shaoqi Li, Wenyue Shi, Futing Xue, Qing Liu, Tahira Naz, Hassan Mohamed, Yuanda Song

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Multifaceted Role of Nanomaterials in Modulating In Vitro Seed Germination, Plant Morphogenesis, Metabolism and Genetic Engineering by Ashutosh Pathak, Shamshadul Haq, Neelam Meena, Pratibha Dwivedi, Shanker Lal Kothari, Sumita Kachhwaha

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Genetically engineered mouse models of cancer reveal new insights about the antitumor immune response by DuPage, Michel J., Jacks, Tyler E.

“…Cells of the immune system are critical components of this extrinsic network of cancer regulators, contributing significantly to the microenvironment of most cancers and either promoting or inhibiting the initiation and progression of this disease. Genetically engineered mouse (GEM) mouse models of spontaneous cancer are starting to shape our understanding of how antitumor T cells may act to prevent or inhibit cancer progression in some settings and not others. …”
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Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma by Politi, Katerina, Song, Xiaoling, Pirun, Mono, Kim-Kiselak, Caroline, Platt, James T., Lee, Emily, Hodges, Emily, Rosebrock, Adam P., Bronson, Roderick T., Socci, Nicholas D., Hannon, Gregory J., Varmus, Harold, McFadden, David Glenn, Bhutkar, Arjun, Chen, Frances K., Santiago, Philip M., Jacks, Tyler E.

“…Genetically engineered mouse models (GEMMs) of cancer are increasingly being used to assess putative driver mutations identified by large-scale sequencing of human cancer genomes. …”
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Genetically Engineered Alginate Lyase-PEG Conjugates Exhibit Enhanced Catalytic Function and Reduced Immunoreactivity by Lamppa, John W., Ackerman, Margaret E., Lai, Jennifer I., Scanlon, Thomas C., Griswold, Karl E.

“…To effectively deimmunize one therapeutic candidate while maintaining high level catalytic proficiency, a combined genetic engineering-PEGylation strategy was implemented. …”
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A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families by Vyas, Valmik K., Barrasa, M. Inmaculada, Fink, Gerald R

“…The lack of meiosis coupled with the absence of plasmids makes genetic engineering cumbersome, especially for essential functions and gene families. …”
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Genetic engineering of shewanella oneidensis MR-1 for boosting electricity output in microbial fuel cells by A, Maria Margret

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Genetic engineering of tomato fruit for sustained accumulation of polyamines during ripening to study their physiological role(s) by Mattoo, A, Cassol, T, Mehta, R, Ali, N, Abdul-Baki, A, Handa, A

Genetically engineered metal ion binding sites on the outside of a Channel's transmembrane beta-barrel. by Kasianowicz, J, Burden, D, Han, L, Cheley, S, Bayley, H

“…We are exploring the ability of genetically engineered versions of the Staphylococcus aureus alpha-hemolysin (alphaHL) ion channel to serve as rationally designed sensor components for analytes including divalent cations. …”

The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation by Jones, J, O'Hare, E, Wong, L

An asymptotic analysis of the malonyl-CoA route to 3-hydroxypropionic acid in genetically engineered microbes by Dalwadi, M, King, J

Suppression subtractive hybridization versus next-generation sequencing in plant genetic engineering: challenges and perspectives by Sahebi, Mahbod, Musa, Mohamed Hanafi, Azizi, Parisa, Hakim, Md. Abdul, Ashkani, Sadegh, Abiri, Rambod

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Engineering the farm : the social and ethical aspects of agricultural biotechnology/ by Bailey, Britt, Lappe', Marc

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Exploring the High Performance Computing-Enablement of a Suite of Gene-Knockout Based Genetic Engineering Applications by Li, Zhenya, Sinnott, Richard O., Choon, Yee Wen, Sjaugi, Muhammad Farhan, Mohd Saberi, Mohamad, Safaai, Deris, Suhaimi, Napis, Omatu, Sigeru, Corchado, Juan Manuel, Zuwairie, Ibrahim, Zulkifli, Md. Yusof

“…Genetic engineering provides methods to modify the genes of microorganisms to achieve desired effects. …”
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Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology by Damien Lemoine, Sarah Mondoloni, Jérome Tange, Bertrand Lambolez, Philippe Faure, Antoine Taly, Ludovic Tricoire, Alexandre Mourot

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Genetically engineered IgG1 and nanobody oligomers acquire strong intrinsic CD40 agonism by Nienke Hesen, Mohamed Anany, Andre Freidel, Mediya Baker, Daniela Siegmund, Olena Zaitseva, Harald Wajant, Isabell Lang

“…We proved here the hypothesis that oligomeric and oligovalent anti-CD40 antibody variants generated by genetic engineering display high intrinsic, thus FcγR-independent, agonistic activity. …”
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Development of a Genetically Engineered Bivalent Vaccine against Porcine Epidemic Diarrhea Virus and Porcine Rotavirus by Wan Li, Mingkai Lei, Zhuofei Li, Huimin Li, Zheng Liu, Qigai He, Rui Luo

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Giant cell arteritis. Part III. New trends in its treatment (role of genetically engineered drugs) by Azamat Makhmudovich Satybaldyev

“…The evidence supporting the use of methotrexate, as well as genetically engineered agents (GEAs), infliximab, etanercept) as steroid-sparing agents is discussed. …”
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