Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice by Longjie Sun, Zheng Lv, Xuexue Chen, Rong Ye, Shuang Tian, Chaofan Wang, Xiaomei Xie, Lu Yan, Xiaohong Yao, Yujing Shao, Sheng Cui, Juan Chen, Jiali Liu

“…Specific deletion of Srsf1 in mouse germ cells impairs homing of precursor SSCs leading to male infertility. …”
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Molding immortality from a plastic germline by Raz, Amelie A, Yamashita, Yukiko M

“…Germ cells are uniquely capable of maintaining cellular immortality, allowing them to give rise to new individuals in generation after generation. …”
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Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. by Arnold, S, Robertson, E

“…Recent advances have uncovered details of the molecular circuits that tightly control cell growth and differentiation in the mammalian embryo from the blastocyst stage, through the establishment of initial anterior-posterior polarity, to gastrulation, when the germ cells are set aside and the three primary germ layers are specified. …”

Concepts, History, Principles, and Application of Germplasm Cryopreservation Technology by Huiping Yang, Terrence R. Tiersch

“… Germplasm are living genetic resources that can serve as bearers of heredity, and include germ cells and their precursors, plant seeds and pollen, animal sperm, oocytes, embryos, and larvae. …”
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Research progress on the mechanism of mesenchymal stem cells therapy for premature ovarian failure by Bayalige, HAN Xia, YUN Sheng

“…The specific mechanism can be a direct differentiation into granulosa cells or inhibition of their apoptosis through the homing effect of MSCs or differentiate into primordial germ cells. Benefit of MSCs can also be attributed to ovarian angiogenesis promotion, immune regulation, reduce oxidative stress response and paracrine, all potentially promote recovery of ovarian function, and thus improve the fertility of women of childbearing age.…”
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Research progress on mitochondrial translocation of human telomerase reverse transcriptase by HU Wei-kai, LIU Rui-xia, YIN Cheng-hong

“…Human telomerase reverse transcriptase(hTERT) is mainly expressed in germ cells, embryonic stem cells and tumor cells, only a few expressed in normal cell. hTERT is mainly located in nucleus and also distributed in mitochondria. hTERT migration from nucleus into mitochondria is called the mitochondrial translocation of hTERT. …”
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Development of the internal reproductive organs in early nymphal stages of Archegozetes longisetosus Aoki (Acari, Oribatida, Trhypochthoniidae) as obtained by synchrotron X-ray mic... by Paavo Bergmann, Michael Heethoff

“…Volume increase of the ovary and a growing number of germ cells indicate proliferation of oogonia in the deutonymph. …”
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Cellular Reproduction / by Coates, Kasey, author 648753

“…Somatic cells, or normal diploid cells of the body, go through mitosis in order to reproduce themselves through cell division, whereas diploid germ cells (ie, primary spermatocytes and primary oocytes) go through meiosis in order to create haploid gametes (ie, sperm and ova) for the purpose of sexual reproduction.…”
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Sevoflurane inhibited reproductive function in male mice by reducing oxidative phosphorylation through inducing iron deficiency by Xue Zhang, Yong Zuo, Jianhua Zhang, Di Zhang, Muhammad Naeem, Yanzhong Chang, Zhenhua Shi

“…Iron levels also significantly reduced in germ cells which decrease the number of germ cells, including sperm, Sertoli cells, and primary spermatocyte. …”
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Two complementary approaches for efficient isolation of Sertoli cells for transcriptomic analysis by Jana Petrusová, Jasper Manning, Jan Kubovčiak, Michal Kolář, Dominik Filipp

“…They directly interact with and support the development of germ cells, thus have an indispensable role in the process of spermatogenesis. …”
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Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells by Qianqian Jiang, Qiannan Di, Dandan Shan, Qian Xu

“…SCs have a high aerobic glycolytic flux to ensure sufficient lactate for germ cells as central energy metabolite, and hypoxia-inducible factors 1alpha (HIF-1α) is a major regulator of glycolysis. …”
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Germline-related molecular phenotype in Metazoa: conservation and innovation highlighted by comparative transcriptomics by Giovanni Piccinini, Liliana Milani

“…The molecular toolkit expressed in germ cells has a high degree of conservation between species, and it also shares many components with the molecular phenotype of some animal totipotent cell lineages, like planarian neoblasts and sponge archaeocytes. …”
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Interdependent transcription of a natural sense/antisense transcripts pair (SLC34A1/PFN3) by Zinad, H, Sae-Lee, C, Ariza-Mateos, M, Adamson, G, Khazeem, M, Knox, A, Chung, G, Mann, J, Werner, A

“…In germ cells, however, recent evidence suggests different biological roles for NATs that require RNA complementarity and double-stranded RNA formation. …”

The Expression Patterns of Human Cancer-Testis Genes Are Induced through Epigenetic Drugs in Colon Cancer Cells by Mikhlid H. Almutairi, Turki M. Alrubie, Bader O. Almutairi, Abdullah M. Alamri, Abdulwahed F. Alrefaei, Maha M. Arafah, Mohammad Alanazi, Abdelhabib Semlali

“…Background: The expression of human germline genes is restricted to the germ cells of the gonads, which produce sperm and eggs. …”
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Primary retroperitoneal teratoma in a young woman: a case report by Nadeem Iqbal, Mahnoor Aitzaz Khan, Ibrahim Khalil, Adnan Ali, Haris Aleem, Nadeem Bin Nusrat

“…They originate from the germ cells that have failed to migrate to normal anatomical destinations. …”
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Cryopreservation of testicular tissue: an alternative to maintain the reproductive capacity in different animal species by David Baruc Cruvinel Lima, Lúcia Daniel Machado da Silva

“…In the last decade, significant progress has been made in obtaining viable and functional germ cells from testicular tissue. However, more research is needed to better establish protocols that can be used in clinical practice with various species.…”
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Sacrococcygeal spindle cell tumour: A case report by Zahra Khalaf, Saeed Al Hindi

“…Sacrococcygeal masses may arise from the axial skeleton, cartilaginous tissue, connective tissue nerve cells, germ cells, or plasma cells. The aid of clinical examinations, imaging, and collaboration with other disciplines is often needed. …”
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Genetic and Epigenetic Regulation of <i>Drosophila</i> Oocyte Determination by Brigite Cabrita, Rui Gonçalo Martinho

“…Primary oocyte determination occurs in many organisms within a germ line cyst, a multicellular structure composed of interconnected germ cells. However, the structure of the cyst is itself highly diverse, which raises intriguing questions about the benefits of this stereotypical multicellular environment for female gametogenesis. …”
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A Brief Overview of Radiation-Induced Effects on Spermatogenesis and Oncofertility by Hisanori Fukunaga, Akinari Yokoya, Kevin M. Prise

“…The genotoxicity of radiation on germ cells may be passed on to the next generation, thus its elucidation is not only a scientific issue but also an ethical, legal, and social issue in modern society. …”
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Pure ovarian choriocarcinoma - an aggressive and rare entity by Priyanka Narang, Shivani, Parveen Rana, Pinkey Lakra, Vijayata Sangwan, Kulvinder Singh

“…Pure ovarian choriocarcinomas are exceedingly rare cancers that develop from either the ovary's gestational tissue (ovarian ectopic pregnancy) or the ovary's pure germ cells. They are divided into two types: gestational ovarian choriocarcinoma (GCO) and non-gestational choriocarcinoma (NGC) based on their origin (NGCO). …”
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