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2141
GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo
Published 2021-03-01“…Following fertilization, the genomes of the germ cells are reprogrammed to form the totipotent embryo. …”
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Article -
2142
The Cellular Impact of the ZIKA Virus on Male Reproductive Tract Immunology and Physiology
Published 2020-04-01“…ZIKV can infect and persist in testicular somatic and germ cells, as well as spermatozoa, leading to cell death and testicular atrophy. …”
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Article -
2143
Immune cell dynamics in male reproductive health: orchestrating immune privilege and inflammatory responses
Published 2024-02-01“…The testis, an immune-privileged organ, possesses a specialized immune microenvironment that shields germ cells (GCs) from autoimmune attacks and orchestrates immune defenses against pathogens. …”
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Article -
2144
Heat stress and stallion fertility
Published 2023-07-01“…In this review, we emphasize upon the impact of heat stress on spermatogenesis and the somatic and germ cells and describe the subsequent testicular alterations. …”
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Article -
2145
Effects of DNA Methylation on Gene Expression and Phenotypic Traits in Cattle: A Review
Published 2023-07-01“…Studies have shown that methylation levels in bovine primordial germ cells, the rearrangement of methylation during embryonic development and abnormal methylation during placental development are all closely related to their reproductive processes. …”
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2146
MSCT of epithelial ovarian tumours : a pictorial illustration
Published 2011“…The classification of ovarian tumours is based on the presumed cell of origin either epithelial, germ cells or specialized gonadal stroma tumour. Among the malignant type of ovarian tumours, the epithelial type is the commonest comprising about 85% of cases. …”
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Proceeding Paper -
2147
Differences in gonadal tissue cryopreservation practices for differences of sex development across regions in the United States
Published 2023-01-01“…Gonads of individuals with DSD can contain germ cells and precursors and patients interested in future fertility preservation and hormonal restoration can participate in DSD-specific research protocols to cryopreserve this tissue. …”
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Article -
2148
Interdependent Transcription of a Natural Sense/Antisense Transcripts Pair (<em>SLC34A1/PFN3</em>)
Published 2022-02-01“…In germ cells, however, recent evidence suggests different biological roles for NATs that require RNA complementarity and double-stranded RNA formation.…”
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Article -
2149
Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos
Published 2023-07-01“…Shortened telomeres can be lengthened by the enzyme telomerase and alternative lengthening of telomeres in germ cells, early embryos, stem cells, and activated lymphocytes. …”
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Article -
2150
Assessment of Culture Condition and In Vitro Colonization Ability of Human Spermatogonial Stem Cells: A Review Article
Published 2013-06-01“…These stem cells, called spermatogonial stem cells (SSCs), are in the base of seminiferous tubules and have the ability of self-renewal and differentiation into functional germ cells. Due to this ability, SSCs can restore spermatogenesis after testicular damage caused by cytotoxic materials or following transplantation into an infertile recipient. …”
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Article -
2151
Description of the stages and scale of maturity for gonads of female pollock
Published 2017-09-01“…Three types of the filiform gonads are defined, containing whether male or female germ cells or connective tissue. The true synchronous type of hermaphroditism is determined for pollock.…”
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Article -
2152
THE ROLE OF MITOCHONDRIA IN THE FORMATION OF THE BIOPHYSICAL POTENTIAL OF THE BODY AND THE MANIFESTATION OF HETEROSIS
Published 2023-05-01“…A new hypothesis has been proposed, according to which heterosis is explained by the relationship between genetic heterozygosity and the high initial potential of free energy of germ cells, caused by increased work and reproduction of mitochondria. …”
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Article -
2153
Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Published 2016-01-01“…The MAGE (melanoma associated antigen) protein family are tumour-associated proteins normally present only in reproductive tissues such as germ cells of the testis. The human genome encodes over 60 MAGE genes of which one class (containing MAGE-A3 and MAGE-A4) are exclusively expressed in tumours, making them an attractive target for the development of targeted and immunotherapeutic cancer treatments. …”
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Article -
2154
Effect of cisplatin on pancreas and testes in Wistar rats: biochemical parameters and histology
Published 2019-08-01“…Histopathological sections of the pancreatic tissue showed marked vasoconstriction and micro infiltration were observed however testicular tissue showed degeneration in some somniferous tubules and also greatly depleted of germ cells in cisplatin treated group. Conclusion: These findings demonstrated that the cisplatin could be induced diabetes and testicular toxicity due to their free radical mediated oxidative stress.…”
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2155
Primary Retroperitoneal Carcinomas: New Insights into Pathogenesis and Clinical Management in Comparison with Ovarian Carcinomas and Carcinoma of Unknown Primary
Published 2023-09-01“…Mucinous carcinoma, which develops in both women and men, may originate in both primordial germ cells and Walthard cell nests that may be derived from the fallopian tube. …”
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Article -
2156
Recent Advances in the Genetic, Anatomical, and Environmental Regulation of the <i>C. elegans</i> Germ Line Progenitor Zone
Published 2020-07-01“…This review describes the recent progress that has been made in characterizing the undifferentiated germ cells and gonad anatomy, and presents open questions in the field and new directions for research to pursue.…”
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Article -
2157
Impact of Environmental Pollution on Female Reproduction
Published 2022-06-01“…Greater consequences are faced by the women as the number of germ cells present in the ovary is fixed during fetal life, and which are nonrenewable. …”
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2158
Canine and Feline Testicular Preservation
Published 2022-01-01“…Although advances have been achieved with the use of testicular fragments to obtain viable and functional germ cells, the establishment of protocols that can be used in clinical routine have not been concluded yet. …”
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Article -
2159
Epiblast ground state is controlled by canonical Wnt/β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells.
Published 2013-01-01“…Cell transplantation revealed that EpiSCs were able to contribute to primordial germ cells and descendants of all three germ layers in a host embryo, suggesting that they maintained pluripotency, even after prolonged culture with XAV939. …”
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Article -
2160
APC/C(Cdh1) enables removal of Shugoshin-2 from the arms of bivalent chromosomes by moderating Cyclin-Dependent Kinase Activity.
Published 2017“…In mammalian females, germ cells remain arrested as primordial follicles. …”
Journal article