RETRACTED ARTICLE: Extremely Active Nano-formulation of Resveratrol (XAR™) attenuates and reverses chemotherapy-induced damage in mice ovaries and testes by Sagar Chhabria, Vaishnavi Takle, Nripen Sharma, Prashant Kharkar, Kshama Pansare, Anish Tripathi, Ashish Tripathi, Deepa Bhartiya

“…Besides effect on numbers of primordial and growing follicles and spermatogenesis, the effect of XAR™ was also evaluated on the transcripts specific for ovarian/testicular stem/progenitor/germ cells, their proliferation, differentiation, meiosis, and the antioxidant indices. …”
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Sexual dimorphic regulation of recombination by the synaptonemal complex in C. elegans by Cori K Cahoon, Colette M Richter, Amelia E Dayton, Diana E Libuda

“…In sexually reproducing organisms, germ cells faithfully transmit the genome to the next generation by forming haploid gametes, such as eggs and sperm. …”
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Adverse effects of endocrine disruptors on the foetal testis development: focus on the phthalates. by Catherine Pairault, HervĂŠ Coffigny, Christine Levacher, Charlotte LĂŠcureuil, Romain Lambrot, Abdelali Lehraiki, Vincent Muczynski, RenĂŠ Habert, Delphine Moison, RenĂŠ Frydman, Virginie Rouiller-Fabre

“…In this system, addition of 10-4 M MEHP (mono-2-ethylhexyl phthalate), the most produced phthalate, had no effect on basal or LH-stimulated production of testosterone, but it reduced the number of germ cells by increasing their apoptosis, without modification of their proliferation. …”
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Transgenerational Transcriptomic and DNA Methylome Profiling of Mouse Fetal Testicular Germline and Somatic Cells after Exposure of Pregnant Mothers to Tributyltin, a Potent Obesog... by Keiko Shioda, Junko Odajima, Bruce Blumberg, Toshi Shioda

“…To address the effects of TBT exposure on germ cells, we exposed pregnant transgenic OG2 mouse dams (F0), which specifically express EGFP in germline cells, to an environmentally relevant dose of TBT or DMSO throughout gestation through drinking water. …”
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Features of the formation of pathogenetic changes of the placental complex on the background of intra-uteronomy infection by Alisa Hoshovska

“…Under the influence of various factors, namely infectious factors, which, depending on the biological specificity, negatively affect the germ cells of the parents, the development of the embryo, the formation of the trophoblast and the placenta, which in turn leads to a violation of the function of the placental complex and gestational complications during pregnancy. …”
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Effect of Folic Acid by injection and supplementary on growth and puberty of Karadi male lambs. by Ismael Othman Karim, Chowman Aladdin Omar

“…While using FA by supplementation and injection significantly (p>0.05) on the diameter and circumference of seminiferous tubules, germ cells thickness, and lumen diameters. …”
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Loss-of-function CFTR p.G970D missense mutation might cause congenital bilateral absence of the vas deferens and be associated with impaired spermatogenesis by Jian-Wen Hou, Xiao-Liang Li, Li Wang, Cong-Ling Dai, Na Li, Xiao-Hui Jiang, Yue-Qiu Tan, Er-Po Tian, Qin-Tong Li, Wen-Ming Xu

“…Thus, this study indicated that the CFTR p.G970D missense mutation might be a pathogenic mutation for CBAVD in Chinese males and associated with impaired spermatogenesis by affecting the proliferation of germ cells.…”
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The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice by Yaru Wang, Wen Zong, Wenli Sun, Chengyan Chen, Zhao-Qi Wang, Tangliang Li

“…Furthermore, <i>Mcph1</i>-Δe8 mice were sterile because of a loss of germ cells in the testis and ovary. The embryonic fibroblasts of <i>Mcph1</i>-Δe8 mice exhibited premature chromosome condensation (PCC). …”
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The Role of ZIP9 and Androgen Receptor in the Establishment of Tight Junctions between Adult Rat Sertoli Cells by Hassan Kabbesh, Ahmed Bulldan, Lutz Konrad, Georgios Scheiner-Bobis

“…This dynamic structure, which establishes an immune-privileged environment protecting haploid germ cells formed in puberty from cells of the innate immune system, protects male fertility. …”
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Mural granulosa cell gene expression associated with oocyte developmental competence by Jiang Jin-Yi, Xiong Huiling, Cao Mingju, Xia Xuhua, Sirard Marc-Andre, Tsang Benjamin K

“…Paracrine interactions between somatic and germ cells are critical for normal follicular development and oocyte maturation. …”
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The current state of the problem of in vitrogene pool preservation in poultry by Y. L. Silyukova, O. I. Stanishevskaya, N. V. Dementieva

“…The review reflects the results of recent research in the field of cryopreservation of female and male germ cells, embryonic cells, the search for new ways in the field of genetic diversity in vitro (the development of new cryoprotective media and new conservation technologies: freeze-drying). …”
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ZDHHC19 Is Dispensable for Spermatogenesis, but Is Essential for Sperm Functions in Mice by Shuai Wang, Hongjie Qiao, Pengxiang Wang, Yuan Wang, Danian Qin

“…Spermatogenesis was not disrupted in <i>Zdhhc19</i> knockout mice, in which properly developed TRA98+ germ cells, SYCP3+ spermatocytes, and TNP1+ spermatids/spermatozoa were detected in seminiferous tubules. …”
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Association of rs4648551 polymorphism in p73 gene in Iranian woman with idiopathic recurrent pregnancy loss by Somayeh Tabasi, Seyed Mostafa Hoseini

“…Regarding to the effective role of p73 gene in the process of primary blastocyst division and protection of germ cells, it seems that rs4648551 polymorphism in this p73 gene be associated with the occurrence of spontaneous abortion symptoms. …”
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Male infertility along with the era of coronavirus infection SARS-CoV-2 by N. G. Kulchenko, N. K. Druzhinina, G. I. Myandina

“…It is known that due to the high expression of ACE2 in spermatogonia, Leydig and Sertoli cells, the testicle, as an organ producing male germ cells, is a potential target for the COVID‑19 virus, which directly affects the reproductive health of men. …”
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Ontological differences in first compared to third trimester human fetal placental chorionic stem cells by Jones, G, Moschidou, D, Puga-Iglesias, T, Kuleszewicz, K, Vanleene, M, Shefelbine, S, Bou-Gharios, G, Fisk, N, David, A, De Coppi, P, Guillot, P

“…We showed that e-CSC shared a common phenotype with l-CSC, differentiating down the osteogenic, adipogenic and neurogenic pathways, and containing a subset of cells endogenously expressing NANOG, SOX2, c-MYC, and KLF4, as well as an array of genes expressed in pluripotent stem cells and primordial germ cells, including CD24, NANOG, SSEA4, SSEA3, TRA-1-60, TRA-1-81, STELLA, FRAGILIS, NANOS3, DAZL and SSEA1. …”

Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and... by Williams, K, McKinnell, C, Saunders, P, Walker, M, Fisher, J, Turner, K, Atanassova, N, Sharpe, M

“…The main findings were as follows: (i) all cell types that express AR also express one or both ERs at all stages of development; (ii) Sertoli cell expression of ERbeta occurs considerably earlier in development than does expression of AR; (iii) most germ cells, including fetal gonocytes, express ERbeta but not AR; (iv) treatment with high, but not low, doses of potent oestrogens such as DES and EE, induces widespread structural and cellular abnormalities of the testis and reproductive tract before puberty; (v) the latter changes are associated with loss of immunoexpression of AR in all affected tissues and a reduction in Leydig cell volume per testis; (vi) none of the effects in (iv) and (v) can be duplicated by treating with high-dose octylphenol or bisphenol A; (vi) none of the reproductive tract changes in (iv) and (v) can be induced by simply suppressing androgen production (GnRHa treatment) or action (flutamide treatment); and (vii) the adverse changes induced by high-dose DES (iv and v) can be largely prevented by co-administration of testosterone. …”

Smad-Independent BMP Signaling in Somatic Cells Limits the Size of the Germline Stem Cell Pool by Chen-Yuan Tseng, Yu-Han Su, Shun-Min Yang, Kun-Yang Lin, Chun-Ming Lai, Elham Rastegari, Oyundari Amartuvshin, Yueh Cho, Yu Cai, Hwei-Jan Hsu

“…BMP-Tkv signaling in the soma limits BMP signals within the GSC niche via Egfr and Hh signaling to ensure that germ cells outside of the niche undergo proper differentiation. …”
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A Z-Linked E3 Ubiquitin Ligase <i>Cs-rchy1</i> Is Involved in Gametogenesis in Chinese Tongue Sole, <i>Cynoglossus semilaevis</i> by Yuxuan Sun, Ying Zhu, Peng Cheng, Mengqian Zhang, Na Wang, Zhongkai Cui, Min Wei, Wenteng Xu

“…In situ hybridization showed that <i>Cs-rchy1</i> was mainly localized in germ cells, that is, spermatid and spermatozoa in testis and stage I, II and III oocytes in ovary. …”
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Proteomic analysis of the mouse sperm acrosome - towards an understanding of an organelle with diverse functionality by Tereza Otčenášková, Eliška Macíčková, Jana Vondráková, Michaela Frolíková, Katerina Komrskova, Romana Stopková, Pavel Stopka

“…Using an indirect immunofluorescence assay, we demonstrated that lipocalin 5 (LCN5) is expressed in the mouse germ cells, and after completing spermatogenesis, it remains localized in the sperm acrosome until the last step of the extratesticular maturation, the acrosome reaction. …”
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Expression profiles of meiotic genes in male vs. female gonads and gametes: Insights into fertility issues by Marília Körbes Rockenbach, Lucas Rosa Fraga, Lucas Rosa Fraga, Lucas Rosa Fraga, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Maria Teresa Vieira Sanseverino, Maria Teresa Vieira Sanseverino, Maria Teresa Vieira Sanseverino

“…Gametes are specialized cells that, at fertilization, give rise to a totipotent zygote capable of generating an entire organism. Female and male germ cells undergo meiosis to produce mature gametes; however, sex-specific events of oogenesis and spermatogenesis contribute to specific roles of gametes in reproductive issues. …”
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