Evidence of reduced recombination rate in human regulatory domains by Ernst, Jason, Liu, Yaping, Sarkar, Abhishek Kulshreshtha, Kheradpour, Pouya, Kellis, Manolis

“…Moreover, by using only the overlap of functional links and DNA methylation in germ cells, we are able to predict the recombination rate with high accuracy. …”
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Stage-Dependent Expression of Protein Gene Product 9.5 in Donkey Testes by Yeonju Choi, Youngwook Jung, Seongmin Kim, Junyoung Kim, Heejun Jung, Minjung Yoon

“…Molecular markers can be used to identify and isolate specific developmental stages of germ cells and Leydig cells. Protein gene product (PGP)9.5 expression in spermatogonia and Leydig cells has been reported in several species. …”
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Melatonin Alleviates BPA-Induced Testicular Apoptosis and Endoplasmic Reticulum Stress by Qi Qi, Lei Feng, Jingjing Liu, Da Xu, Guoqing Wang, Xiaoyan Pan

“…Results: Melatonin promoted the development of seminiferous tubules, restored the orderly arrangement of the germ cells, and increased epithelial layers in the seminiferous tubules in BPA-treated mice. …”
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Effects of Ocimum tenuiflorum on Induced Testicular Degeneration by Filgrastim in Wistar Rats by G. S Tuimah Alabedi, H. F AL-Baghdady, M. A Alahmer, G. S Bustani, A. M. B Al-Dhalimy

“…The results showed that filgrastim administration leads to the degeneration of spermatozoa and germ cells in the testicles of rats. The results of the current study showed that O. tenuiflorum has some ameliorating effects on the testicles and fertility of the rats which were treated with filgrastim. …”
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A Novel Non-Allelic Homologous Recombination Event in a Parent with an 11;22 Reciprocal Translocation Leading to 22q11.2 Deletion Syndrome by Steven Pastor, Oanh Tran, Daniel E. McGinn, T. Blaine Crowley, Elaine H. Zackai, Donna M. McDonald-McGinn, Beverly S. Emanuel

“…The ability to fully delineate an individual’s 22q11.2 regional structure will likely be important for studies designed to assess an unaffected individual’s risk for generating rearrangements in germ cells, potentially leading to offspring with 22q11.2DS. …”
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Protective Role of Peroxiredoxins against Reactive Oxygen Species in Neonatal Rat Testicular Gonocytes by Cristian O’Flaherty, Annie Boisvert, Gurpreet Manku, Martine Culty

“…Although PRDXs are abundant in the testis and spermatozoa, their potential role at different phases of spermatogenesis and in perinatal germ cells is unknown. Here, we examined the expression and role of PRDXs in isolated rat neonatal gonocytes, the precursors of spermatogonia, including spermatogonial stem cells. …”
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Stereological Study of Mouse Testicular Tissue Treated with Zinc Oxide Nanoparticles and N-Acetyl Cysteine by M Mahmoodi, N Darbandi, Z Khosravi

“…At the end of the treatment, mean weight and volume of testicles, length and diameter of seminiferous tubules, height of germinal epithelium and number of germ cells were evaluated. Findings: In the group of zinc oxide nanoparticles, a significant decrease was observed in volume (38.86±1.48), length (0.89±0.09), diameter (162.69±1.03), and height of germinal epithelium (41.06±1.73) of the seminiferous tubules, number of spermatogonia (4.15±0.11) ×106, spermatocytes (21.45±0.83) ×106, round spermatid (22.31±0.47) ×106, elongated spermatid (21.74±0.76) ×106 and Sertoli cell (3.08±0.10) ×106 and a significant increase was observed in interstitial tissue volume (18.04±1.84) compared to the control group (p<0.001). …”
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Aedes aegypti exhibits a distinctive mode of late ovarian development by Heng Zhang, Feng Guang Goh, Lee Ching Ng, Chun Hong Chen, Yu Cai

“…First, during larval stage, Ae. aegypti primordial germ cells (PGCs) undergo a cyst-like proliferation with synchronized divisions and incomplete cytokinesis, leading to the formation of one tightly packed “PGC mass” containing several interconnected cysts, different from D. melanogaster PGCs that divide individually. …”
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Effects of Anthropic Pollutants Identified in Pampas Lakes on the Development and Reproduction of Pejerrey Fish Odontesthes bonariensis by Leandro A. Miranda, Leandro A. Miranda, Gustavo M. Somoza, Gustavo M. Somoza

“…Moreover, in all cases pyknotic cells, corresponding to the degeneration of the germ cells, were observed in the testes of exposed fish. …”
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Expression of SPAG7 and its regulatory microRNAs in seminal plasma and seminal plasma-derived extracellular vesicles of patients with subfertility by Masood Abu-Halima, Lea Simone Becker, Mohammad A. Al Smadi, Lea Sophie Kunz, Laura Gröger, Eckart Meese

“…Sperm-associated antigen 7 (SPAG 7) is expressed in male germ cells and plays a crucial role in several biological functions associated with sperm production and maturation. …”
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Characteristics of symptomatic epilepsy and other neurological disorders in children with lissencephaly by V. I. Guzeva, I. V. Ochrim, V. R. Kasumov, O. V. Guzeva, V. V. Guzeva, N. E. Maksimova

“…The probable cause of the deterioration is considered to be the “Transportation” function-specific astrocytes and radial glial fibers involved in the migration of germ cells. The absence of convolutions in the mature brain – morphological substrate is agyria full lissencephaly, the presence of only a single, rudimentary and thickened gyri (pachygyria) – incomplete lissencephaly. …”
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Characteristics of biochemical parameters of sperm production of carp sire when using hulled oats in feeding during the pre-spawning period by N. Syrovatka, I. Hrytsyniak, D. Syrovatka, I. Yaremchuk

“…Considering the increase in the productivity of fish sperm, in particular, the increase in the number of sperm with rectilinear motion, the decrease in the number of lifeless sperm and changes in the protein formula of germ cells, it was established that it is advisable to add hulled oats to the main diet in the amount of 30%. …”
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Neuroplastin Expression in Male Mice Is Essential for Fertility, Mating, and Adult Testosterone Levels by Juanjuan Chen, Xiao Lin, Soumee Bhattacharya, Caroline Wiesehöfer, Gunther Wennemuth, Karin Müller, Dirk Montag

“…Leydig, Sertoli, peritubular myoid, and germ cells express Np, but spermatogenesis and sperm number are not affected in <i>Nptn^−/−</i> males. …”
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Improving Interpretation of Biopsies During Microsurgical Testicular Sperm Exploration in Azoospermic Patients: Use of Davidson’s Fluid by Laurence AARON GALEA, Sue STURROCK, Sree APPU, Daniel LANTSBERG, Darren KATZ

“…Background: Histological interpretation of testicular biopsies in the investigation of infertility in men with azoospermia requires adequate tissue fixation to preserve the nuclear and cytoplasmic detail, as well as the architectural organisation of germ cells in different phases of maturation within seminiferous tubules. …”
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Protein Expression and Bioinformatics Study of Granulosa Cells of Polycystic Ovary Syndrome Expressed Under the Influence of DHEA by Pankaj Pant, Reema Sircar, Ritu Prasad, Hari Om Prasad, Havagiray R Chitme

“…Background: The reproductive system is heavily dependent on ovarian follicles, which are made up of germ cells (oocytes) and granulosa cells (GCs), including cumulus granulosa cells (CGCs) and mural granulosa cells (MGCs). …”
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mTORC1 signaling pathway regulates tooth repair by Honghong Liu, Yu Yue, Zhiyun Xu, Li Guo, Chuan Wu, Da Zhang, Lingfei Luo, Wenming Huang, Hong Chen, Deqin Yang

“…Taking advantage of the NTR/Mtz system, the dlx2b + tooth germ cells were depleted by Mtz effectively. The process of tooth germ repair was evaluated by antibody staining, in situ hybridization, EdU staining and alizarin red staining. …”
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Exposure to endosulfan can cause long term effects on general biology, including the reproductive system of mice by Anju Sharma, Arigesavan Kaninathan, Sumedha Dahal, Susmita Kumari, Bibha Choudhary, Sathees C. Raghavan

“…Endosulfan exposure induced DNA damage and mutations in germ cells at the molecular level. Interestingly, even after 8 months of endosulfan exposure, we observed increased DNA breaks in reproductive tissues. …”
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What the distribution of sperm size can tell about the stability of spermatogenesis in hybrid frogs Pelophylax esculentus by A. Fedorova, E. Pustovalova

“…Some males (8/24) even produced meiotic chromosomal plates with 26 bivalents (i.e. 4n germ cells) which may testify about the ability to produce diploid sperm. …”
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Gonadal Development in European Eel Populations of North Adriatic Lagoons at Different Silvering Stages by Laura Gentile, Antonio Casalini, Pietro Emmanuele, Riccardo Brusa, Annalisa Zaccaroni, Oliviero Mordenti

“…Histological observations of germ cells at the light microscopy level allowed for the characterization of six steps of oocyte maturation. …”
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Medaka factor in the germline alpha (figα) is indispensable for oogenesis but not for gonadal sex differentiation by Katsuyasu Kamimura, Masato Kinoshita, Akira Kanamori

“…Previous studies showed that medaka lacking germ cells have morphologically abnormal gonads and female to male sex reversal occurred. …”
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