The Beginning of Meiosis in Mammalian Female Germ Cells: A Never-Ending Story of Intrinsic and Extrinsic Factors by Donatella Farini, Massimo De Felici

“…Meiosis is the unique division of germ cells resulting in the recombination of the maternal and paternal genomes and the production of haploid gametes. …”
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A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes by Carmell, Michelle A, Dokshin, Gregoriy A, Skaletsky, Helen, Hu, Yueh-Chiang, van Wolfswinkel, Josien C, Igarashi, Kyomi J, Bellott, Daniel W, Nefedov, Michael, Enders, George C, Uversky, Vladimir N, Mello, Craig C, Reddien, Peter, Page, David C

“…We report an ancient family of GCNA (germ cell nuclear antigen) proteins that arose in the earliest eukaryotes, and feature a rapidly evolving intrinsically disordered region (IDR). …”
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Genetic dissection of germ cell migration and the distinction between gonadal mesoderm and fat body development in drosophila by Moore, Lisa A. (Lisa Anne), 1969-

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Dppa3 / Pgc7 / stellais a maternal factor and is not required for germ cell specification in mice by Bortvin, Alex, Goodheart, Mary L., Liao, Michelle, Page, David C.

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Mir-290–295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects by Medeiros, Lea Ann, Dennis, Lucas M., Gill, Mark E., Houbaviy, Hristo, Markoulaki, Styliani, Fu, Dongdong, White, Amy C., Kirak, Oktay, Sharp, Phillip A., Jaenisch, Rudolf, Page, David C

“…Male mir-290–295−/− mice, due to the extended proliferative lifespan of their germ cells, are able to recover from this initial germ cell loss and are fertile. …”
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The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells by Okumura, Leah M., Lesch, Bluma J., Page, David C.

“…In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. …”
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Periodic retinoic acid–STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis by Endo, Tsutomu, Romer, Katherine A., Anderson, Ericka L., Baltus, Andrew E., de Rooij, Dirk G., Page, David C

“…Competencies for both transitions begin while RA levels are low, so that the germ cells respond as soon as RA levels rise. Together with other findings, our results demonstrate that periodic RA–STRA8 signaling intersects with periodic germ-cell competencies to regulate two distinct, cell-type-specific responses: spermatogonial differentiation and meiotic initiation. …”
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Suprasellar germ cell tumours: specific problems and the evolution of optimal management with a combined chemoradiotherapy regimen. by Janmohamed, S, Grossman, AB, Metcalfe, K, Lowe, D, Wood, D, Chew, S, Monson, J, Besser, G, Plowman, P

“…OBJECTIVE: Suprasellar germ cell tumours are rare, and there are few series of patients outlining the problems in diagnosis and management, and providing clear guidelines for optimal therapy. …”

Nut directs p300-dependent, genome-wide H4 hyperacetylation in male germ cells by Shiota, H, Barral, S, Buchou, T, Tan, M, Couté, Y, Charbonnier, G, Reynoird, N, Boussouar, F, Gérard, M, Zhu, M, Bargier, L, Puthier, D, Chuffart, F, Bourova-Flin, E, Picaud, S, Filippakopoulos, P, Goudarzi, A, Ibrahim, Z, Panne, D, Rousseaux, S, Zhao, Y, Khochbin, S

“…Shiota et al. show the oncogenic factor Nut is expressed in post-meiotic male germ cells, where it recruits p300 and/or CBP and enhances histone H4K5 and H4K8 acetylation, leading to histone-to-protamine replacement.…”

Paternal age effect mutations in germ cell development: pathological correlates in normal testis and testicular tumours by Lim, J

“…Recently, spermatocytic seminoma (SS; a rare testicular germ cell tumour that occurs mainly in older men) has emerged as a key link between the processes of somatic and germline mutation (Goriely <em>et al, Nat Genet.…”

Development of a best-practice clinical guideline for the use of bleomycin in the treatment of germ cell tumours in the UK by Watson, R, De La Peña, H, Tsakok, M, Joseph, J, Stoneham, S, Shamash, J, Joffe, J, Mazhar, D, Traill, Z, Ho, L, Brand, S, Protheroe, A

“…Bleomycin, a cytotoxic chemotherapy agent, forms a key component of curative regimens for lymphoma and germ cell tumours. It can be associated with severe toxicity, long-term complications and even death in extreme cases. …”

Ribosome Synthesis and MAPK Activity Modulate Ionizing Radiation-Induced Germ Cell Apoptosis in Caenorhabditis elegans by Eberhard, R, Stergiou, L, Hofmann, E, Hofmann, J, Haenni, S, Teo, Y, Furger, A, Hengartner, M

“…In parallel, rpoa-2(op259) leads to reduced Ras/MAPK pathway activity, which is required for germ cell progression and physiological germ cell death. …”

Actions and Roles of FSH in Germinative Cells by Kaiana Recchia, Amanda Soares Jorge, Laís Vicari de Figueiredo Pessôa, Ramon Cesar Botigelli, Vanessa Cristiane Zugaib, Aline Fernanda de Souza, Daniele dos Santos Martins, Carlos Eduardo Ambrósio, Fabiana Fernandes Bressan, Naira Caroline Godoy Pieri

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Testicular tumors by Giovanni Rosti, Ornella Carminati, Claudia Casanova, Giorgio Papiani

Subjects: “…Testicle - Seminoma - Germ cell tumors…”
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Metastatic Mature Teratoma Presented with Massive Intraabdominal Bleeding: A Case Report by Oktay Büyükaşık, A.Oğuz Hasdemir, H.Ali Kılıçgün

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Toxic Effects of Nonylphenol on Neonatal Testicular Development in Mouse Organ Culture by Hyun-Jung Park, Mingtian Zhang, Won-Young Lee, Kwon-Ho Hong, Jeong Tae Do, Chankyu Park, Hyuk Song

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Mature teratoma of liver in an adult male patient by Firdos Saba, Tahira Hamid, Hamzeh Younes M Alrawashdeh, Mohammad Shahid Iqbal, Aisha Tabassum

Subjects: “…germ cell tumor…”
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Testicular tumors by Giovanni Rosti, Ornella Carminati, Claudia Casanova, Giorgio Papiani

Subjects: “…Testicle - Seminoma - Germ cell tumors…”
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Growing Teratoma Syndrome—A Clinicoradiological Series by Sheena Prineethi, Aparna Irodi, Anu Eapen, Sharon Milton, Anjana Joel

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Effects of CRISPR/Cas9-mediated dnd1 knockout impairs gonadal development in striped catfish by Kunlanan Booncherd, Somkiat Sreebun, Pailin Pasomboon, Surintorn Boonanuntanasarn

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