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1441
Effects of pharmacological doses of niacin on subacute glucocorticoid‐induced testicular damage in rats
Published 2023-10-01“…Hypospermatogenesis, germ cell degeneration and depletion, epithelial vacuolization, and degenerated Leydig cells were observed in PC rats. …”
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1442
Cooperative cell–cell actin network remodeling to perform Gap junction endocytosis
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1443
Increased collective migration correlates with germline stem cell competition in a basal chordate.
Published 2023-01-01“…Often the donor GSCs win, and completely replace the gametes of the recipient- a process called germ cell parasitism (gcp). gcp is a heritable trait, and winner and loser genotypes can be found in nature and reared in the lab. …”
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1444
Ovarian cell aggregate culture in teleost, marine medaka (Oryzias dancena): basic culture conditions and characterization
Published 2024-03-01“…Moreover, they were able to maintain minimal ovarian function such as germ cell maintenance and E2 synthesis for a short period. …”
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1445
Characterization of rare histological subtypes of ovarian cancer based on molecular profiling
Published 2023-01-01“…This study aimed to perform the molecular profiling of rare malignant ovarian tumors, including non‐epithelial tumors (NETs; germ cell tumors and sex cord tumors) and clear cell carcinoma (CCC), to determine how they differ from the major HGSCs. …”
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1446
Pure testicular choriocarcinoma with gastrointestinal metastasis and paraneoplastic symptoms: a case report
Published 2023-06-01“…Abstract Background Pure testicular choriocarcinoma is a rare type of non-seminomatous germ cell tumor extremely poor prognostic with the tendency to bleed at the metastatic site. …”
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1447
Evaluation of human bone marrow mesenchymal stem cells in the treatment of non obstructive azoospermia
Published 2024-03-01“…Such patients usually have testicular biopsy of germ cell aplasia or spermatogenic arrest. In recent decades, Mesenchymal Stem Cells (MSCs) had been studied thoroughly and proved safe and effective regarding their capability for trans-differentiation into different cell types. …”
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1448
SETDB1 Regulates Porcine Spermatogonial Adhesion and Proliferation through Modulating <i>MMP3/10</i> Transcription
Published 2022-01-01“…These results illustrate the significance of SETDB1 in modulating early male germ cell development.…”
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1449
Seasonal Expression of Gonadotropin Genes in the Pituitary and Testes of Male Plateau Zokor (<i>Eospalax baileyi</i>)
Published 2022-03-01“…During the non-breeding season (September), the relative testes weight and the seminiferous tubule diameter were significantly reduced. All germ cell types were observed during the breeding season (May), whereas only spermatogonia were observed during the non-breeding season. …”
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1450
Testis Sparing Surgery in Pediatric Testicular Tumors
Published 2020-10-01“…The majority of pediatric patients with benign germ cell tumors (GCTs) (mean age: 3.7 years) and sex cord-stromal tumors (SCSTs) (mean age: 6.6 years) were treated with TSS, 61.9% and 61.2%, respectively. …”
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1451
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.
Published 2013-01-01“…We found that inactivation of Wt1 resulted in massive germ cell death and only SCs were present in most of the seminiferous tubules which was very similar to NOA in humans. …”
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1452
Anti-N-methyl-D-aspartate receptor encephalitis: A paraneoplastic syndrome in an Indian adolescent girl
Published 2023-01-01“…A right adnexal cystic solid mass was identified in the abdominal ultrasound with the radiological appearance of an ovarian teratoma or germ cell tumor on MRI. Alpha-fetoprotein levels were raised. …”
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1453
Dysregulation of Immature Sertoli Cell Functions by Exposure to Acetaminophen and Genistein in Rodent Cell Models
Published 2023-07-01“…Sertoli cells are essential for germ cell development and function. Their disruption by endocrine disrupting chemicals (EDCs) or drugs could jeopardize spermatogenesis, contributing to male infertility. …”
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1454
Distribution of Ovarian Tumors in Zonguldak Karaelmas University Hospital. Between 2001 and 2007
Published 2008-04-01“…Distribution of 123 ovarian tumors: 73.2% (90) were benign, 7.3% (9) were borderline tumors and 19.5% (24) were malignant. 68 of the cases (55.3%) were surface epithelial-stromal tumor; 34 of the cases (27.7%) were germ cell tumors; 10 of the cases (8.1%) were sex cord-stromal tumors; one of the cases (0.8%) was vascular tumor and 10 of the cases (8.1%) were metastatic tumors. …”
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1455
Mast cell hyperactivity as the factor in the pathogenesis of male infertility
Published 2022-03-01“…Moreover, in severe spermatogenesis disorders (Sertoli cell-only syndrome, Germ cell aplasia), mast cells were found both in the peritubular space and in the lumen of the convoluted seminiferous tubules. …”
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1456
Defensive Role of Vitamin E Against Nitrosamine-Induced Harm to Testicular Tissues in Male BALB/C Albino Mice
Published 2023-12-01“…Additionally, severe necrosis and germ cell erosion were observed. In contrast, results from the vitamin E-treated animals exhibited favorable changes in the testicular and epididymis tissues when compared to the nitrosamine-exposed group and the control group. …”
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1457
JAK-STAT-dependent contact between follicle cells and the oocyte controls Drosophila anterior-posterior polarity and germline development
Published 2024-02-01“…Abstract The number of embryonic primordial germ cells in Drosophila is determined by the quantity of germ plasm, whose assembly starts in the posterior region of the oocyte during oogenesis. …”
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1458
Formation of ovarian reserve
Published 2018-09-01“…The size of the ovarian reserve depends on the genes involved in proliferation and differentiation of germ cells, sexual differentiation, meiosis, germ cell degeneration, the formation of primary follicles, and the potential mechanism for self-renewal of embryonic stem cells. …”
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1459
Primary endodermal sinus tumor originating from the sacral ligament: a case report and review of the literature
Published 2023-07-01“…Conclusion Extra-gonadal germ cell tumors are rarely reported. When young teenagers complain of acute lower abdominal pain with elevated AFP, but there was no lesion in bilateral ovaries and fallopian tubes, we must think about the possibility of endodermal sinus tumors. …”
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1460
Effect of Varicocelectomy on Restoration of Spermatogenesis in Patients with Non-obstructive Azoospermia
Published 2019-06-01“…As a result of pathological evaluation, hypospermatogenesis, maturation arrest and germ cell aplasia were found in 34.4%, 31.2% and 34.4% of patients, respectively. …”
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