The hematological parameters in testicular cancer by Selahattin Çalışkan, Selçuk Kaba, Emrah Özsoy, Orhan Koca, Mehmet Akyüz, Metin İshak Öztürk

“…The area under curve was 0.645, 0.626, 0.578 for NLR, neutrophil and lymphocyte counts for the diagnosis of TCa. Mixed germ cell tumor was the most common histologic subtype with an incidence of 51.58%(n:65 patients) and seminomas were reported 37.30% (n:47 patients) of the patients. …”
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Ovarian teratoma in children: a plea for collaborative clinical study by Justyna Łuczak, Maciej Bagłaj

“…Abstract Background Although teratomas are the most common histologic subtype of childhood ovarian germ cell tumors, their appropriate treatment in this age group still remains unclear. …”
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CFTR mutations causing congenital unilateral absence of the vas deferens (CUAVD) and congenital absence of the uterus (CAU) in a consanguineous family by Mahdieh Daliri Ghouchanatigh, Ranjha Khan, Majid Mojarrad, Uzma Hameed, Muhammad Zubair, Ahmed Waqas, Mohsen Jalali, Mahmoudreza Kalantari, Ali Shamsa, Huan Zhang, Qing-Hua Shi

“…Testicular biopsy of one patient was performed, and hematoxylin and eosin (H and E) staining of testis sections displayed the presence of germ cell types ranging from spermatogonia to mature spermatids, indicating obstructive azoospermia. …”
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Y chromosome in Turner syndrome: review of the literature by Rose Mary Rocco de Oliveira, Ieda Therezinha do Nascimento Verreschi, Monica Vannucci Nunes Lipay, Lilian Piñero Eça, Alexis Dourado Guedes, Bianca Bianco

“…Even though gonadoblastoma is a benign tumor, it can undergo transformation into invasive dysgerminoma in 60% of the cases, and also into other, malignant forms of germ cell tumors. Although some authors have questioned the high incidence of gonadoblastoma (around 30%), the risk of developing any kind of gonadal lesion, whether tumoral or not, justifies investigation of Y-chromosome sequences by means of the polymerase chain reaction (PCR), a highly sensitive, low-cost and easy-to-perform technique. …”
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Chronic consumption of contaminated feed with 2,4-dichlorophenoxyacetic acid (2,4-D) herbicide in rodents: effects on male reproductive health by Jamile Silveira Tomizzi Simões, Douglas Gonçalves, Gisele Alborghetti Nai, Renata Calciolari Rossi, Ana Paula Favareto

“…There was a negative impact on sperm morphology and plasma membrane integrity in MCG and HCG, respectively. Germ cell exfoliation within the lumen of the seminiferous tubules and epithelial vacuolization in epididymis were found in the HCG. …”
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The histology and the proapoptotic control in the ipsilateral and the contralateral testes following unilateral vasectomy by Aydin Ismet Hazar, Basri Cakiroglu, Ertan Sakalli, Mustafa Bahadir Can Balci, Erkan Eyyupoglu, Tuncay Tas, Orhun Sinanoglu, Pinar Tuzlali, Nusret Can Cilesiz

“…Conclusion: The procedure causes destruction in the testicular structure by causing bilateral intratubular germ cell necrosis, unilateral obstruction, increase in the tubular pressure and processes that are aggravated by some probable autoimmune reactions.…”
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Propagation of human germ stem cells in long-term culture by Abbas Khodadadi, Akram Eidi, Mohammad Reza Sadeghi, Mahmood Jeddi-Tehrani, Arash Mohazzab, Mohammad Mehdi Akhondi, Zeinab Piravar

“…Background: Spermatogonial stem cells (SSCs), a subset of undifferentiated type A spermatogonia, are the foundation of complex process of spermatogenesis and could be propagated in vitro culture conditions for long time for germ cell transplantation and fertility preservation. …”
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Ubiquitin-Proteasome System–Regulated Protein Degradation in Spermatogenesis by Yi Xiong, Chao Yu, Qianting Zhang

“…Spermatogenesis is a prolonged and highly ordered physiological process that produces haploid male germ cells through more than 40 steps and experiences dramatic morphological and cellular transformations. …”
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PDCL2 is essential for spermiogenesis and male fertility in mice by Minyan Li, Yuxi Chen, Jianping Ou, Junjiu Huang, Xiya Zhang

“…As a member of the phosducin family, chaperonin-related Pdcl2, a germline-specific gene, may be involved in germ cell protein folding. Given that PDCL2 is highly conserved in evolution, it may be indispensable for mammalian spermiogenesis; however, the function of PDCL2 in higher mammalian species remains unknown. …”
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REV7 in Cancer Biology and Management by Yoshiki Murakumo, Yasutaka Sakurai, Takuya Kato, Hiroshi Hashimoto, Masaaki Ichinoe

“…Although REV7 principally functions in the fields of DNA repair and cell cycle regulation, many binding partners of REV7 have been identified using comprehensive analyses in the past decade, and the significance of REV7 is expanding in various other biological fields, such as gene transcription, epigenetics, primordial germ cell survival, neurogenesis, intracellular signaling, and microbial infection. …”
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Alpha-fetoprotein-elevated postpubertal testicular teratoma with retroperitoneal metastasis on 18F-FDG PET/CT: case report and literature review by Hao Jiao, Yongkang Qiu, Wenpeng Huang, Yongbai Zhang, Zhao Chen, Aixiang Wang, Lei Kang

“…However, the patient had a significantly increased level of AFP, and 18F-FDG PET/CT showed the retroperitoneal metastasis had increased FDG uptake, with a SUVmax of 15.6, suggesting the coexistence of other germ cell tumor components, and the patient might have a poor prognosis. …”
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The Study of the Expression of <i>CGB1</i> and <i>CGB2</i> in Human Cancer Tissues by Piotr Białas, Aleksandra Śliwa, Anna Szczerba, Anna Jankowska

“…Even though the protein products of these genes have not yet been identified, based on The Cancer Genome Atlas (TCGA) database analysis we showed that the mutual presence of <i>CGB1</i> and <i>CGB2</i> transcripts is a characteristic feature of cancers of different origin, including bladder urothelial carcinoma, cervical squamous cell carcinoma, esophageal carcinoma, head and neck squamous cell carcinoma, ovarian serous cystadenocarcinoma, lung squamous cell carcinoma, pancreatic adenocarcinoma, rectum adenocacinoma, testis germ cell tumors, thymoma, uterine corpus endometrial carcinoma and uterine carcinosarcoma.…”
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JAK Inhibition Prevents DNA Damage and Apoptosis in Testicular Ischemia-Reperfusion Injury via Modulation of the ATM/ATR/Chk Pathway by Farah Khashab, Farah Al-Saleh, Nora Al-Kandari, Fatemah Fadel, May Al-Maghrebi

“…Testicular ischemia reperfusion injury (tIRI) causes oxidative stress-induced DNA damage leading to germ cell apoptosis (GCA). The aim of the study is to establish a direct link between JAK2 activation and the DNA damage response (DDR) signaling pathways and their role in tIRI-induced GCA using AG490, a JAK2 specific inhibitor. …”
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Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature by Negar Safaei, Hooman Kamran, Mohammad Hossein Anbardar, Mohammadreza Bordbar, Omid Reza Zekavat, Mehdi Forooghi

“…Teratoma is a type of germ cell tumor layer that appears in the gonadal, sacrococcygeal, mediastinal, and retroperitoneal regions. …”
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Down-Regulation of Neogenin Decreases Proliferation and Differentiation of Spermatogonia during the Early Phase of Spermatogenesis by Jin Woo Park, Yu Jin Kim, Sang Jin Lee, Jung Jae Ko, Dae Keun Kim, Jae Ho Lee

“…We analyzed the expression profiles of germ cell factors by RT-PCR and Western blotting. Neogenin localized mainly to spermatogonia in seminiferous tubules of mouse testes. …”
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Sarcomatoid (Spindle Cell) Carcinoma Arising in Mature Cystic Teratoma as a Mural Nodule: A Case Report by Renu Sukumaran, Suchetha Sambasivan

“…Mature cystic teratomas are the most common ovarian germ cell tumours.Malignant transformation is rare in mature cystic teratoma. …”
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Prognostic Gene Expression, Stemness and Immune Microenvironment in Pediatric Tumors by David Stahl, Rainer Knoll, Andrew J. Gentles, Christian Vokuhl, Andreas Buness, Ines Gütgemann

“…A high stemness score (mRNAsi) correlates with clinical and morphologic subtype in Wilms tumors, neuroblastomas, synovial sarcomas, atypical teratoid rhabdoid tumors and germ cell tumors. In neuroblastomas, a high mRNAsi is associated with shortened overall survival. …”
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A conserved role of bam in maintaining metabolic homeostasis via regulating intestinal microbiota in Drosophila by Jiale Wang, Yangyang Zhu, Chao Zhang, Renjie Duan, Fanrui Kong, Xianrui Zheng, Yongzhi Hua

“…Background Previous studies have proven that bag-of-marbles (bam) plays a pivotal role in promoting early germ cell differentiation in Drosophila ovary. However, whether it functions in regulating the metabolic state of the host remains largely unknown. …”
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Neck Dermoid Cyst with Rare Imaging Appearance on Ultrasound, Elastography, and Computed Tomography by Vadlamudi Nagendra, Suresh Vasant Phatak, Prerna Anup Patwa, Suhasini Pattabiraman, Ghanta Prashanti

“…Dermoid cyst is a type of inclusion cyst and a benign cystic teratoma containing two or more germ cell layers. It can show variable appearance on ultrasound and Computed Tomography (CT) as it is derived from squamous cell epithelium (ectoderm) and contains dermal-derived elements such as skin appendages, hair follicles, sebaceous and sweat glands. …”
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Chicken Testicular Stem Cells by Pavel Trefil, Jitka Mucksová, Jiri Kalina

“…Transplantation of male germ cells into sterilized recipients in chicken opened a new approach for chicken transgenesis as well as for preservation of endangered bird species. …”
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