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Helicobacter pylori infection can affect energy modulating hormones and body weight in germ free mice
Published 2015“…To assess whether a H. pylori infection could affect growth in early life, we determined the expression levels of selected metabolic gut hormones in germ free (GF) and specific pathogen-free (SPF) mice with and without the presence of H. pylori. …”
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Journal Article -
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Metronidazole causes skeletal muscle atrophy and modulates muscle chronometabolism
Published 2018“…PPARγ and one of its important target genes, adiponectin, are also upregulated by metronidazole. Metronidazole in germ-free (GF) mice increases the expression of other core clock genes, such as Bmal1 and Per2, as well as the metabolic regulators FoxO1 and Pdk4, suggesting a microbiota-independent pharmacologic effect. …”
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Journal Article -
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The gut microbiota and developmental programming of the testis in mice
Published 2014“…Here we used specific pathogen free (SPF) mice and germ-free (GF) mice to explore whether gut microbiota and/or their metabolites can influence testis development and regulation of BTB. …”
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Journal Article