Developmental brain changes during puberty and associations with mental health problems by Niousha Dehestani, Sarah Whittle, Nandita Vijayakumar, Timothy J. Silk

“…Mixed-effects models were used to investigate associations between pubertal timing and regional and global brain development. Mediation models were used to investigate the indirect effect of pubertal timing on mental health problems via brain development. …”
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Impact of functional MRI data preprocessing pipeline on default-mode network detectability in patients with disorders of consciousness by Adrian eAndronache, Cristina eRosazza, Davide eSattin, Matilde eLeonardi, Ludovico eD'Incerti, Ludovico eMinati

“…Starting from a standard preprocessing pipeline, additional steps were gradually inserted, namely band-pass filtering, removal of co-variance with the movement vectors, removal of co-variance with the global brain parenchyma signal, rejection of realignment outlier volumes and ventricle masking. …”
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Measuring acute effects of subanesthetic ketamine on cerebrovascular hemodynamics in humans using TD-fNIRS by Adelaida Castillo, Julien Dubois, Ryan M. Field, Frank Fishburn, Andrew Gundran, Wilson C. Ho, Sami Jawhar, Julian Kates-Harbeck, Zahra M. Aghajan, Naomi Miller, Katherine L. Perdue, Jake Phillips, Wesley C. Ryan, Mahdi Shafiei, Felix Scholkmann, Moriah Taylor

“…Furthermore, ketamine led to a brain-wide reduction in the fractional amplitude of low frequency fluctuations, and a decrease in the global brain connectivity of the prefrontal region. Lastly, we provide preliminary evidence that a combination of neural and physiological metrics may serve as predictors of subjective mystical experiences and reductions in depressive symptomatology. …”
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A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes by Blaise Robert, Eyal Y Kimchi, Yurika Watanabe, Tatenda Chakoma, Miao Jing, Yulong Li, Daniel B Polley

“…Rostral BFCNs in the horizontal limb of the diagonal band were more responsive to reward omission, more accurately classified behavioral outcomes, and more closely tracked fluctuations in pupil-indexed global brain state. Caudal tail BFCNs in globus pallidus and substantia innominata were more responsive to unconditioned auditory stimuli, orofacial movements, aversive reinforcement, and showed robust associative plasticity for punishment-predicting cues. …”
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An extensive basal ganglia hemorrhage in a preexisting neonatal asphyxiated lesion after mRNA-based SARS-CoV-2 vaccination: A fatal adult case of cerebral palsy by Tomoyuki Takano, Masahiro Ito

“…Urgent brain computed tomography (CT) revealed extensive left basal ganglia hemorrhage with global brain edema and downward herniation of the brainstem. …”
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Discourse-Level Information Recall in Early and Late Bilinguals: Evidence From Single-Language and Cross-Linguistic Tasks by Isabelle Chou, Jiehui Hu, Edinson Muñoz, Adolfo M. García, Adolfo M. García, Adolfo M. García, Adolfo M. García, Adolfo M. García

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Evidence for Structural and Functional Alterations of Frontal-Executive and Corticolimbic Circuits in Late-Life Depression and Relationship to Mild Cognitive Impairment and Dementi... by Neda Rashidi-Ranjbar, Neda Rashidi-Ranjbar, Dayton Miranda, Meryl A. Butters, Benoit H. Mulsant, Benoit H. Mulsant, Aristotle N. Voineskos, Aristotle N. Voineskos

“…Our data synthesis revealed that in some but not all studies, impairment of both frontal-executive and corticolimbic circuits, as well as impairment of global brain topology was present in LLD, MCI, and LLD+MCI vs. …”
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Alterations in white matter microstructure in neurofibromatosis-1. by Katherine H Karlsgodt, Tena Rosser, Evan S Lutkenhoff, Tyrone D Cannon, Alcino Silva, Carrie E Bearden

“…Prior neuroimaging findings indicate global brain volume increases, consistent with neural over-proliferation. …”
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Predicting Post-Stroke Somatosensory Function from Resting-State Functional Connectivity: A Feasibility Study by Xiaoyun Liang, Chia-Lin Koh, Chun-Hung Yeh, Peter Goodin, Gemma Lamp, Alan Connelly, Leeanne M. Carey

“…Functional connectivity was employed to model the global brain function. Behavioral measures and MRI were collected at the same timepoint. …”
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Large-scale brain networks and intra-axial tumor surgery: a narrative review of functional mapping techniques, critical needs, and scientific opportunities by Timothy F. Boerger, Peter Pahapill, Alissa M. Butts, Alissa M. Butts, Elsa Arocho-Quinones, Manoj Raghavan, Max O. Krucoff, Max O. Krucoff

“…We then explore how brain tumors might teach us more about mechanisms of global brain dysfunction and recovery through pre- and postoperative longitudinal connectomic and behavioral analyses.…”
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Increased Stability and Breakdown of Brain Effective Connectivity During Slow-Wave Sleep: Mechanistic Insights from Whole-Brain Computational Modelling by Beatrice M. Jobst, Rikkert Hindriks, Helmut Laufs, Enzo Tagliazucchi, Gerald Hahn, Adrián Ponce-Alvarez, Angus B. A. Stevner, Morten L. Kringelbach, Gustavo Deco

“…We used whole-brain computational modelling to study the differences in global brain functional connectivity and synchrony of fMRI activity in healthy humans during wakefulness and slow-wave sleep. …”
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Testing the feasibility of a primary-care exercise intervention to prevent and reverse early frailty and build resilience in community-dwelling older adults by John Travers, Roman Romero-Ortuno, Marie-Therese Cooney

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Alteration of the Oligodendrocyte Lineage Varies According to the Systemic Inflammatory Stimulus in Animal Models That Mimic the Encephalopathy of Prematurity by Geraldine Favrais, Geraldine Favrais, Cindy Bokobza, Elie Saliba, Sylvie Chalon, Pierre Gressens

“…These white matter abnormalities are embedded in more global brain damage defining the encephalopathy of prematurity (EoP). …”
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Navigating the multiple dimensions of the creativity-mental disorder link: a Convergence Mental Health perspective by David G. Angeler, Erin Smith, Michael Berk, Agustín Ibáñez, Harris A. Eyre

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Loss of 'small-world' networks in Alzheimer's disease: graph analysis of FMRI resting-state functional connectivity. by Ernesto J Sanz-Arigita, Menno M Schoonheim, Jessica S Damoiseaux, Serge A R B Rombouts, Erik Maris, Frederik Barkhof, Philip Scheltens, Cornelis J Stam

“…<h4>Conclusions/significance</h4>We present evidence of AD-induced changes in global brain functional connectivity specifically affecting long-distance connectivity. …”
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Short-term mechanisms influencing volumetric brain dynamics by Nikki Dieleman, Huiberdina L. Koek, Jeroen Hendrikse

“…Mechanisms that decrease global brain volume are: fluid restriction, evening MRI measurements, corticosteroids, antipsychotics and short-term effects of pathological processes like Alzheimer's disease, hypertension and Diabetes mellitus type II. …”
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Experimental Pharmacology in Transgenic Rodent Models of Alzheimer’s Disease by A. Claudio Cuello, A. Claudio Cuello, A. Claudio Cuello, Hélène Hall, Sonia Do Carmo

“…The application of SAM was intended to revert the global brain DNA hypomethylation unleashed by the intraneuronal accumulation of amyloid-β-immunoreactive material, an intervention that restored levels of DNA methylation including of the bace1 gene. …”
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Cellular and neurochemical basis of sleep stages in the thalamocortical network by Giri P Krishnan, Sylvain Chauvette, Isaac Shamie, Sara Soltani, Igor Timofeev, Sydney S Cash, Eric Halgren, Maxim Bazhenov

“…The link between the combined action of neuromodulators in the brain and global brain states remains a mystery. In this study, using biophysically realistic models of the thalamocortical network, we identified the critical intrinsic and synaptic mechanisms, associated with the putative action of acetylcholine (ACh), GABA and monoamines, which lead to transitions between primary brain vigilance states (waking, non-rapid eye movement sleep [NREM] and REM sleep) within an ultradian cycle. …”
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The relationship between isolated hypertension with brain volumes in UK Biobank by Danielle Newby, Laura Winchester, William Sproviero, Marco Fernandes, Upamanyu Ghose, Donald Lyall, Lenore J. Launer, Alejo J. Nevado‐Holgado

“…In this study, we compared a variety of global brain measures between participants with isolated hypertension to those with normal blood pressure (BP) or systolic‐diastolic hypertension using the largest cohort of healthy individuals. …”
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Connectomic Insights into Topologically Centralized Network Edges and Relevant Motifs in the Human Brain by Mingrui eXia, Qixiang eLin, Yanchao eBi, Yong eHe

“…However, the topological roles of WM tracts in global brain communications and their underlying microstructural basis remain poorly understood. …”
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