Association between systolic blood pressure variability and severity of cerebral amyloid angiopathy in incident intracerebral hemorrhage by Tom J. Moullaali, Tom J. Moullaali, Rachel Walters, Mark Rodrigues, Neshika Samarasekera, Jose Bernal, Jose Bernal, Xia Wang, Catherine Humphreys, Joanna M. Wardlaw, Andrew Farrall, Colin Smith, Craig S. Anderson, Craig S. Anderson, Rustam Al-Shahi Salman, Brian McKinstry

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Changes in Brain Lateralization in Patients with Mild Cognitive Impairment and Alzheimer’s Disease: A Resting-State Functional Magnetic Resonance Study from Alzheimer’s Disease Neu... by Hao Liu, Lele Zhang, Qian Xi, Xiaohu Zhao, Xiaohu Zhao, Fei Wang, Xiangbin Wang, Weiwei Men, Weiwei Men, Qixiang Lin

“…By directly comparing the patients with MCI with the patients with AD, an exclusive abnormal rightward laterality was observed in the patients with MCI within the 0.2 ≤ |iLI| < 0.4 threshold, and the normal leftward asymmetry vanished in the patients with AD within the |iLI| ≥ 0.8 threshold.ConclusionGlobal brain lateralization was different among three groups. …”
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Repeatability and Reproducibility of in-vivo Brain Temperature Measurements by Ayushe A. Sharma, Ayushe A. Sharma, Ayushe A. Sharma, Rodolphe Nenert, Rodolphe Nenert, Christina Mueller, Andrew A. Maudsley, Jarred W. Younger, Jerzy P. Szaflarski, Jerzy P. Szaflarski, Jerzy P. Szaflarski, Jerzy P. Szaflarski

“…For each region, the upper and lower bounds of Minimal Detectable Change (MDC) were established to characterize the typical range of TCRE values.Results: The mean global brain temperature over all subjects was 37.2°C with spatial variations across ROIs. …”
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Changes in Cyclin D1, cdk4, and Their Associated Molecules in Ischemic Pyramidal Neurons in Gerbil Hippocampus after Transient Ischemia and Neuroprotective Effects of Ischemic Prec... by Tae-Kyeong Lee, Dae Won Kim, Jae-Chul Lee, Cheol Woo Park, Hyejin Sim, Ji Hyeon Ahn, Joon Ha Park, Myoung Cheol Shin, Jun Hwi Cho, Choong-Hyun Lee, Moo-Ho Won, Soo Young Choi

“…Inadequate activation of cell cycle proteins including cyclin D1 and cdk4 is involved in neuronal cell death induced by diverse pathological stresses, including transient global brain ischemia. The neuroprotective effect of ischemic preconditioning is well-established, but the underlying mechanism is still unknown. …”
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Functional network alterations in young brain tumor patients with radiotherapy-induced memory impairments and vascular injury by Melanie A. Morrison, Sadie Walter, Sadie Walter, Sabine Mueller, Sabine Mueller, Erin Felton, Angela Jakary, Schuyler Stoller, Annette M. Molinaro, Annette M. Molinaro, Steve E. Braunstein, Christopher P. Hess, Christopher P. Hess, Janine M. Lupo

“…Here we use resting-state functional MRI (rsfMRI) to further investigate the complex mechanisms underlying memory impairment after RT.MethodsNineteen young patients previously treated with or without focal or whole-brain RT for a brain tumor underwent cognitive testing followed by 7T rsfMRI and susceptibility-weighted imaging for CMB detection. Global brain modularity and efficiency, and rsfMRI signal variability within the dorsal attention, salience, and frontoparietal networks were computed. …”
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Food-Approach Eating Behaviors and Brain Morphology: The Generation R Study by Olga Dmitrichenko, Olga Dmitrichenko, Olga Dmitrichenko, Olga Dmitrichenko, Yuchan Mou, Yuchan Mou, Trudy Voortman, Trudy Voortman, Tonya White, Tonya White, Pauline W. Jansen, Pauline W. Jansen

“…Lastly, we did not observe significant associations of binge-eating symptoms with global brain measurements and a priori-defined regions of interest, including the right frontal operculum, insular and orbitofrontal cortex. …”
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Associations of body mass index and sarcopenia with screen-detected mild cognitive impairment in older adults in Colombia by Gary O’Donovan, Gary O’Donovan, Olga L. Sarmiento, Philipp Hessel, Philipp Hessel, Graciela Muniz-Terrera, Graciela Muniz-Terrera, Claudia Duran-Aniotz, Claudia Duran-Aniotz, Agustín Ibáñez, Agustín Ibáñez, Agustín Ibáñez, Agustín Ibáñez, Agustín Ibáñez

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An observational treatment study of metacognition in anxious-depression by Celine Ann Fox, Chi Tak Lee, Anna Kathleen Hanlon, Tricia XF Seow, Kevin Lynch, Siobhán Harty, Derek Richards, Jorge Palacios, Veronica O'Keane, Klaas Enno Stephan, Claire M Gillan

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The World Health Organization Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders and the headache revolution: from headache burden to a global action pla... by Matilde Leonardi, Paolo Martelletti, Rami Burstein, Arianna Fornari, Licia Grazzi, Alla Guekht, Richard B. Lipton, Dimos Dimitrios Mitsikostas, Jes Olesen, Mayowa Ojo Owolabi, Elena Ruiz De la Torre, Simona Sacco, Timothy J. Steiner, Nirmal Surya, Takao Takeshima, Cristina Tassorelli, Shuu-Jiun Wang, Tissa Wijeratne, Shengyuan Yu, Alberto Raggi

“…Reducing the burden of headache disorders will not only improve the quality of life and wellbeing of people with headache but also reduce the burden of neurological disorders increasing global brain health and, thus, global population health.…”
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SENSE-Cog Asia: A Feasibility Study of a Hearing Intervention to Improve Outcomes in People With Dementia by Saima Sheikh, Sehrish Tofique, Nosheen Zehra, Rabia Amjad, Maham Rasheed, Maria Usman, Shanker Lal, Emma Hooper, Emma Hooper, Jahanara Miah, Nusrat Husain, Hussain Jafri, Hussain Jafri, Nasim Chaudhry, Iracema Leroi

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Depressive Symptomatology in Early Retirees Associated With Reason for Retirement—Results From the Population-Based LIFE-Adult-Study by Andrea E. Zuelke, Susanne Roehr, Susanne Roehr, Matthias L. Schroeter, Matthias L. Schroeter, A. Veronica Witte, Andreas Hinz, Heide Glaesmer, Christoph Engel, Cornelia Enzenbach, Silke Zachariae, Samira Zeynalova, Markus Loeffler, Arno Villringer, Arno Villringer, Steffi G. Riedel-Heller

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Vast Parameter Space Exploration of the Virtual Brain: A Modular Framework for Accelerating the Multi-Scale Simulation of Human Brain Dynamics by Michiel van der Vlag, Lionel Kusch, Alain Destexhe, Viktor Jirsa, Sandra Diaz-Pier, Jennifer S. Goldman

“…Multi-scale models of brain function have begun to directly link the emergence of global brain dynamics in conscious and unconscious brain states with microscopic changes at the level of cells. …”
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Get Moving! Increases in Physical Activity Are Associated With Increasing Functional Connectivity Trajectories in Typically Aging Adults by Karen A. Dorsman, Karen A. Dorsman, Sophia Weiner-Light, Adam M. Staffaroni, Jesse A. Brown, Amy Wolf, Yann Cobigo, Samantha Walters, Joel H. Kramer, Joel H. Kramer, Kaitlin B. Casaletto

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Linking objective measures of physical activity and capability with brain structure in healthy community dwelling older adults by Anne-Marthe Sanders, Geneviève Richard, Knut Kolskår, Kristine M. Ulrichsen, Tobias Kaufmann, Dag Alnæs, Dani Beck, Erlend S. Dørum, Ann-Marie G. de Lange, Jan Egil Nordvik, Lars T. Westlye

“…We used a multimodal brain imaging approach offering complementary structural MRI based indicators of brain health: global white matter fractional anisotropy (FA) and mean diffusivity (MD) based on diffusion tensor imaging, and subcortical and global brain age based on brain morphology inferred from T1-weighted MRI data. …”
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Apathy, Executive Function, and Emotion Recognition Are the Main Drivers of Functional Impairment in Behavioral Variant of Frontotemporal Dementia by Gada Musa Salech, Gada Musa Salech, Patricia Lillo, Patricia Lillo, Patricia Lillo, Karin van der Hiele, Carolina Méndez-Orellana, Agustín Ibáñez, Agustín Ibáñez, Agustín Ibáñez, Agustín Ibáñez, Andrea Slachevsky, Andrea Slachevsky, Andrea Slachevsky, Andrea Slachevsky

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Alteration of brain network centrality in CTN patients after a single triggering pain by Xiuhong Ge, Xiuhong Ge, Luoyu Wang, Luoyu Wang, Mengze Wang, Mengze Wang, Lei Pan, Haiqi Ye, Xiaofen Zhu, Sandra Fan, Qi Feng, Quan Du, Yu Wenhua, Zhongxiang Ding, Zhongxiang Ding

“…The brain regions which the sDC and dDC values were changing reflect the global brain function of CTN patients, and provides a basis for further exploration of the central mechanism of CTN.…”
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A Novel BrainHealth Index Prototype Improved by Telehealth-Delivered Training During COVID-19 by Sandra Bond Chapman, Julie M. Fratantoni, Ian H. Robertson, Ian H. Robertson, Mark D'Esposito, Geoffrey S. F. Ling, Jennifer Zientz, Stacy Vernon, Erin Venza, Lori G. Cook, Aaron Tate, Jeffrey S. Spence

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Peripheral inflammation levels associated with degree of advanced brain aging in schizophrenia by Federica Klaus, Federica Klaus, Tanya T. Nguyen, Tanya T. Nguyen, Michael L. Thomas, Sharon C. Liou, Benchawanna Soontornniyomkij, Kyle Mitchell, Rebecca Daly, Rebecca Daly, Ashley N. Sutherland, Ashley N. Sutherland, Dilip V. Jeste, Dilip V. Jeste, Dilip V. Jeste, Lisa T. Eyler, Lisa T. Eyler

“…Furthermore, SZ is associated with accelerated global brain aging, as measured by brain structure-based brain predicted age difference (Brain-PAD). …”
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Reduced structural connectivity in cortico-striatal-thalamic network in neonates with congenital heart disease by Megan Ní Bhroin, Samy Abo Seada, Alexandra F. Bonthrone, Christopher J. Kelly, Daan Christiaens, Andreas Schuh, Maximilian Pietsch, Jana Hutter, J-Donald Tournier, Lucillio Cordero-Grande, Daniel Rueckert, Joseph V. Hajnal, Kuberan Pushparajah, John Simpson, A. David Edwards, Mary A. Rutherford, Serena J. Counsell, Dafnis Batalle

“…We performed graph theoretical analyses and network-based statistics (NBS) to assess global brain network topology and identify subnetworks of altered connectivity in infants with CHD prior to cardiac surgery. …”
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Time- and sex-dependent efficacy of magnesium sulfate to prevent behavioral impairments and cerebral damage in a mouse model of cerebral palsy by Ismaël Daher, Bérénice Le Dieu-Lugon, Maryline Lecointre, Nicolas Dupré, Caroline Voisin, Philippe Leroux, Nathalie Dourmap, Bruno J. Gonzalez, Stéphane Marret, Isabelle Leroux-Nicollet, Carine Cleren

“…MgSO4 tended to prevent these motor and cognitive deficits only in females, while it prevented global brain tissue damage in both sexes. Moreover, interindividual and intersexual differences appeared regarding the lesion size and neuroprotection by MgSO4 in a region-specific manner. …”
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