Plasma Campesterol Is Positively Associated with Carotid Plaques in Asymptomatic Subjects by Valéria Sutti Nunes, Edite Vieira Silva de Campos, Jamal Baracat, Victor França, Érica Ivana Lázaro Gomes, Raissa Peres Coelho, Edna Regina Nakandakare, Vanessa Helena Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintão

“…Age, body mass index, systolic and diastolic blood pressure, total cholesterol, non-HDL-C, triglycerides, glucose, and lathosterol/sitosterol ratios correlated positively with cIMT (<i>p</i> ≤ 0.05). …”
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In Situ Water Quantification in Natural Deep Eutectic Solvents Using Portable Raman Spectroscopy by Suha Elderderi, Laura Wils, Charlotte Leman-Loubière, Hugh J. Byrne, Igor Chourpa, Cécile Enguehard-Gueiffier, Emilie Munnier, Abdalla A. Elbashir, Leslie Boudesocque-Delaye, Franck Bonnier

“…Three NADES systems, namely Betaine Glycerol (BG), Choline Chloride Glycerol (CCG) and Glucose Glycerol (GG), containing a range of water concentrations between 0% (<i>w</i>/<i>w</i>) and 28.5% (<i>w</i>/<i>w</i>), were studied. …”
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Antioxidant Polyphenols of <i>Antirhea borbonica</i> Medicinal Plant and Caffeic Acid Reduce Cerebrovascular, Inflammatory and Metabolic Disorders Aggravated by High-Fat Diet-Induc... by Janice Taïlé, Matthieu Bringart, Cynthia Planesse, Jessica Patché, Philippe Rondeau, Bryan Veeren, Patricia Clerc, Anne Gauvin-Bialecki, Steeve Bourane, Olivier Meilhac, David Couret, Marie-Paule Gonthier

“…This study evaluated the effects of the characterized polyphenol-rich extract of <i>Antirhea borbonica</i> medicinal plant and its major constituent caffeic acid on a high-fat diet (HFD)-induced obesity mouse model during ischemic stroke, and murine bEnd3 cerebral endothelial cells in high glucose condition. In vivo, polyphenols administered by oral gavage for 12 weeks attenuated insulin resistance, hyperglycemia, hyperinsulinemia and dyslipidemia caused by HFD-induced obesity. …”
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Correlation between Subclinical Left Ventricular Systolic Function and Diabetic Microvascular Complications in Patients with Type 2 Diabetes by CHEN Yanyan, SHI Min, WANG Yi, FU Jianfang, ZHANG Ying, LIU Xiangyang, ZHANG Weiqing, TA Shengjun, LIU Liwen, LI Zeping, ZHOU Jie, LI Xiaomiao

“…Logistic regression analysis showed that after adjustment for multiple factors of gender, age, duration of diabetes, hypertension, glycosylated hemoglobin, fasting glucose, blood creatinine, heart rate, urinary microalbumin, and LV fraction shortening, GLS was decreased in the T2DM+C (1) group〔OR=0.744, 95%CI (0.601, 0.920) 〕 and the T2DM+C (2 to 3) group〔OR=0.707, 95%CI (0.525, 0.952) 〕 compared with the T2DM alone group (P&lt;0.05). …”
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Bioengineered Carboxymethylcellulose–Peptide Hybrid Nanozyme Cascade for Targeted Intracellular Biocatalytic–Magnetothermal Therapy of Brain Cancer Cells by Alexandra A. P. Mansur, Sandhra M. Carvalho, Luiz Carlos A. Oliveira, Elaine Maria Souza-Fagundes, Zelia I. P. Lobato, Maria F. Leite, Herman S. Mansur

“…They confirmed dual-nanozyme cascade biocatalytic activity targeted by polymer–peptide conjugates (AuNP//Co-MION@CMC_iRGD, ZP = −29 ± 3 mV and D_H = 60 ± 4 nm) to kill brain cancer cells (i.e., bioenergy “<i>starvation</i>” by glucose deprivation and oxidative stress through reactive oxygen species generation), which was boosted by the magneto-hyperthermotherapy effect when submitted to the alternating magnetic field (i.e., induced local thermal stress by “<i>nanoheaters</i>”). …”
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Obstetric and perinatal outcomes of singleton pregnancies conceived via assisted reproductive technology complicated by gestational diabetes mellitus: a prospective cohort study by Azam Kouhkan, Mohammad E. Khamseh, Reihaneh Pirjani, Ashraf Moini, Arezoo Arabipoor, Saman Maroufizadeh, Roya Hosseini, Hamid Reza Baradaran

“…All participants were enrolled after GDM screening through one-step oral glucose tolerance test (OGTT) and then grouped into GDM and non-GDM groups. …”
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The Effect of Probiotics (MCP^® BCMC^® Strains) on Hepatic Steatosis, Small Intestinal Mucosal Immune Function, and Intestinal Barrier in Patients with Non-Alco... by Mohamad Hizami Mohamad Nor, Nurainina Ayob, Norfilza M. Mokhtar, Raja Affendi Raja Ali, Geok Chin Tan, Zhiqin Wong, Nor Hamizah Shafiee, Yin Ping Wong, Muaatamarulain Mustangin, Khairul Najmi Muhammad Nawawi

“…Likewise, no significant changes were found for both groups for the following parameters: LiverFAST analysis (steatosis, fibrosis and inflammation scores), alanine aminotransferase, total cholesterol, triglycerides, and fasting glucose. In the immunohistochemistry (IHC) analysis, no significant expression changes were seen for CD4+ T lymphocytes in either group (probiotics: −0.33 ± 1.67, <i>p</i> = 0.35 vs. placebo: 0.35 ± 3.25, <i>p</i> = 0.63). …”
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Hyperlipidemia and lipid-lowering therapy in diabetic retinopathy (DR): A bibliometric study and visualization analysis in 1993–2023 by Haishan Tan, Xiangyu Fu, Yongjiang Chen, Yujiao Wang, Danian Chen

“…While the roles of blood glucose and blood pressure in the development of retinopathy have been extensively studied, the relationship between body fat and DR pathogenesis and the impact of lipid-reducing drugs on DR has just emerged as a research hotspot in DR study. …”
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Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study by Xingqi Cao, Xueqin Li, Jingyun Zhang, Xiaoyi Sun, Gan Yang, Yining Zhao, Shujuan Li, Emiel O Hoogendijk, Xiaofeng Wang, Yimin Zhu, Heather Allore, Thomas M Gill, Zuyun Liu

“… BackgroundCompared with adults with normal glucose metabolism, those with prediabetes tend to be frail. …”
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Correlation between Adiponectin and Free Testosterone Index and Insulin Resistance in Patients with Polycystic Ovary Syndrome by TANG Zixuan, LI Jing, HUANG Qi, ZHANG Ying, ZHANG Han, WANG Qian, ZHANG Lin, CHENG Yao, LIAO Xin

“…The general data of the research subjects were collected, and laboratory index examinations were conducted: on the 3rd to 5th day of the menstrual cycle of regular menstruation or when there was no dominant follicle in the B-ultrasound examination of irregular menstruation, and the patient&apos;s cubital venous blood was collected on an empty stomach after fasting for 12 hours to detect fasting blood glucose (FPG), fasting insulin (FINS), Glycated hemoglobin (HbA1c), triacylglycerol (TG), total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), follicle stimulating hormone (FSH), luteinizing hormone (LH), progesterone, testosterone (TEST), sex hormone binding globulin (SHGB), dehydroepiandrosterone sulfate (DHEA-S), ADPN. …”
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Transcriptomic comparison of seeds and silique walls from two rapeseed genotypes with contrasting seed oil content by Xupeng Guo, Xupeng Guo, Na Yan, Linpo Liu, Xiangzhen Yin, Yuhong Chen, Yanfeng Zhang, Jingqiao Wang, Guozhi Cao, Chengming Fan, Zanmin Hu, Zanmin Hu

“…During the silique development, silique walls contained more hexose and less sucrose than seeds, and glucose and fructose contents in seeds and silique walls of L192 were higher than that of A260 at 15 DAF, and sucrose content in the silique walls of L192 were lower than that of A260 at three time points. …”
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Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1<i>-iddm</i> Rat, an Animal Model of Human Type 1 Diabetes... by Svetlana Baskal, Stefanos A. Tsikas, Olga Begou, Alexander Bollenbach, Sigurd Lenzen, Anne Jörns, Dimitrios Tsikas

“…Previously, we have shown that combination with anti-TCR/anti-TNF-α antibody-based therapy re-established normoglycemia and increased proteinic arginine-dimethylation in the spleen, yet not in the pancreas. High blood glucose is often associated with elevated formation of advanced glycation end-products (AGEs) which act via their receptor (RAGE). …”
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Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC)—A Possible Role of Lactate Dehydrogenase in Metabolic Flexibility by Julia Brenmoehl, Elli Brosig, Nares Trakooljul, Christina Walz, Daniela Ohde, Antonia Noce, Michael Walz, Martina Langhammer, Stefan Petkov, Monika Röntgen, Steffen Maak, Christina E. Galuska, Beate Fuchs, Björn Kuhla, Siriluck Ponsuksili, Klaus Wimmers, Andreas Hoeflich

“…However, in response to physical exercise, glucose and fatty acid oxidation were stimulated, lactate dehydrogenase activity was reduced, and lactate formation was inhibited in the marathon mice compared with trained control mice. …”
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The Associations of Perceived and Oxidative Stress with Hypertension in a Cohort of Police Officers by Janczura M, Rosa R, Dropinski J, Gielicz A, Stanisz A, Kotula-Horowitz K, Domagala T

“…Out of the MetS components, the effect of waist circumference (OR=1.138, 95% CI [1.064&ndash; 1.218], p=0.0001) and glucose (B=2.696, 95% CI [1.081&ndash; 6.725], p=0.03) were also encountered. …”
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Impact of an integrated care program on glycemic control and cardiovascular risk factors in patients with type 2 diabetes in Saudi Arabia: an interventional parallel-group controll... by Ayla M. Tourkmani, Osama Abdelhay, Hesham I. Alkhashan, Aboud F. Alaboud, Ahmed Bakhit, Tarek Elsaid, Ahmed Alawad, Aljohara Alobaikan, Hala Alqahtani, Abdulaziz Alqahtani, Adel Mishriky, Abdulaziz bin Rsheed, Turki J. Alharbi

“…Glycated hemoglobin (HbA1c), fasting blood glucose (FBG), lipid profiles, and blood pressure (BP) were measured. …”
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Exopolysaccharide from the yeast Papiliotrema terrestris PT22AV for skin wound healing by Masoud Hamidi, Oseweuba Valentine Okoro, Giuseppe Ianiri, Hafez Jafari, Khodabakhsh Rashidi, Saeed Ghasemi, Raffaello Castoria, Davide Palmieri, Cédric Delattre, Guillaume Pierre, Mahta Mirzaei, Lei Nie, Hadi Samadian, Amin Shavandi

“…Results: The obtained EPS was water-soluble and revealed an average molecular weight (Mw) of 202 kDa. Mannose and glucose with 97% and 3% molar percentages, respectively, constituted the EPS. …”
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Molecular Determination of mirRNA-126 rs4636297, Phosphoinositide-3-Kinase Regulatory Subunit 1-Gene Variability rs7713645, rs706713 (Tyr73Tyr), rs3730089 (Met326Ile) and Their Ass... by Rashid Mir, Imadeldin Elfaki, Faisel M. Abu Duhier, Maeidh A. Alotaibi, Adel Ibrahim AlAlawy, Jameel Barnawi, Abdullatif Taha Babakr, Mohammad Muzaffar Mir, Hyder Mirghani, Abdullah Hamadi, Pradeep Kumar Dabla

“…The phosphoinositide 3-kinase (PI3K) is important for insulin signaling and glucose uptake. The genome wide association studies have identified the association of certain loci with diseases including T2D. …”
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社区水平的多学科综合管理对脑梗死患者二级预防效果研究 Effect of Multidisciplinary Management in Community on Secondary Prevention of Cerebral Infarction by 王文科，王志强，袁伟红，于彦，赵琳，王颖，柳德元，鹿月惠

“…The primary observation indictor was ischemic stroke recurrence, the secondary indictors included statin use, antiplatelet therapy, hypertension and diabetes treatment, the control rate of LDL-C, blood pressure and blood glucose, the NIHSS score and moderate-to-severity disability, post-stroke depression occurrence and the awareness rate of health education knowledge. …”
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Clam challenges high concentrations of algae diet environment: Growth performance, metabolism physiology, and related gene expression characteristics by Sishao Fan, Senlei Feng, Shusheng Gan, Siting Wang, Xiafei Liang, Meimei Liu, Zhiguo Dong

“…Furthermore, transcriptome results showed that the expression levels of G6P, IGFBP, CHI3L1, FAS, MyHC, and other genes related to glucose, protein, and fatty acid metabolism of C. sinensis were significantly downregulated in the Diet T3 and Diet T5 groups. …”
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N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1 by Yunhong Shi, Yidan Liu, Caiqing Wu, Xiuxing Liu, Wenfei Hu, Zhenlan Yang, Zhidong Li, Yangyang Li, Caibin Deng, Kun Wei, Chenyang Gu, Xuhao Chen, Wenru Su, Yehong Zhuo

“…Methods Single-cell RNA sequencing (scRNA-seq), molecular docking, and transfection assay were used to explore the effectiveness and pathogenesis of N,N-dimethyl-3β-hydroxycholenamide (DMHCA)-treated mice with RIR injury and DMHCA-treated microglia after oxygen and glucose deprivation/reoxygenation (OGD/R). Results DMHCA could suppress inflammatory gene expression and attenuate neuronal lesions, restoring the retinal structure in vivo. …”
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