Modulation of the Gut Microbiota by Fufang-Zhenzhu-Tiaozhi Capsule Attenuates Hypertension Induced by a High-Fructose and High-Salt Diet by Zhe Chen, Zhe Chen, Zhe Chen, Zhe Chen, Zhe Chen, Bin Yang, Bin Yang, Bin Yang, Bin Yang, Zhen Wang, Zhen Wang, Zhen Wang, Zhen Wang, Xianglu Rong, Xianglu Rong, Xianglu Rong, Xianglu Rong, Qing Zhu, Qing Zhu, Qing Zhu, Qing Zhu, Jiao Guo, Jiao Guo, Jiao Guo, Jiao Guo

“…Hypertension is frequently comorbid with the disorders of glucose and lipid metabolism. The increased intakes of fructose and salt contribute to the development of hypertension and related metabolic disorders, which are closely associated with gut dysbiosis. …”
Get full text

Evolution of Inflammatory and Oxidative Stress Markers in Romanian Obese Male Patients with Type 2 Diabetes Mellitus after Laparoscopic Sleeve Gastrectomy: One Year Follow-Up by Ariana Picu, Laura Petcu, Diana Simona Ştefan, Grațiela Grădișteanu Pîrcălăbioru, Manuela Mitu, Daiana Bajko, Daniela Lixandru, Cristian Guja, Octavian Savu, Anca Pantea Stoian, Alina Constantin, Bogdan Smeu, Cătălin Copăescu, Mariana Carmen Chifiriuc, Elena Ionica, Constantin Ionescu-Tîrgovişte

“…Glycated hemoglobin (HbA1c), blood glucose levels, BMI, weight, visceral fat level, HDL-cholesterol, incretin hormones, proinflammatory and the oxidative stress status were significantly improved in the LSG versus conventional treatment group. …”
Get full text

DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults by Mark A. Burton, Emma S. Garratt, Matthew O. Hewitt, Hanan Y. Sharkh, Elie Antoun, Leo D. Westbury, Elaine M. Dennison, Nicholas C. Harvey, Cyrus Cooper, Julia L. MacIsaac, Michael S. Kobor, Harnish P. Patel, Keith M. Godfrey, Karen A. Lillycrop

“…Abstract Background While ageing is associated with increased insulin resistance (IR), the molecular mechanisms underlying increased IR in the muscle, the primary organ for glucose clearance, have yet to be elucidated in older individuals. …”
Get full text

The relationship between coronary artery calcification and bone metabolic markers in maintenance hemodialysis patients by Lin Xiong, Qi-qi Chen, Yong Cheng, Yong-shu Lan, Jian-bo Yang, Xiang-qiong Wen, Xin Xie, Ting Kang, Wei-hua Wu, Santao Ou

“…Routine laboratory parameters, including triglycerides (TG), total cholesterol (TC), glucose (Glu), calcium (Ca), phosphorus (P), magnesium (Mg), etc., were measured. …”
Get full text

Ingestão de glutamina e maltodextrina duas horas no pré-operatório imediato melhora a sensibilidade à insulina pós-operatória: estudo aleatório, duplo-cego e controlado Ingestion o... by Diana Borges Dock-Nascimento, Jose Eduardo de Aguilar-Nascimento, Dan Linetzky Waitzberg

“…Postoperatively, all patients from the fasting group had abnormal glucose (> 110mg/dl), this abnormality being of 50% when compared to the CHO group (p = 0.14), and of 22.2% when compared to the GLN group (p = 0.01). …”
Get full text

Lean adolescents with increased risk for metabolic syndrome by Emperatriz Molero-Conejo, Luz Marina Morales, Virginia Fernández, Xiomara Raleigh, Maria Esther Gómez, Maritza Semprún-Fereira, Gilberto Campos, Elena Ryder

“…Biochemical measurements included fasting serum insulin, glucose, total cholesterol (TC), triglycerides (Tg), HDL-C, LDL-C and VLDL-C. …”
Get full text

Changes in the Metabolome and Nutritional Quality of Pulp from Three Types of Korla Fragrant Pears with Different Appearances as Revealed by Widely Targeted Metabolomics by Wei Jiang, Pan Yan, Qiangqing Zheng, Zhendong Wang, Qiling Chen, Yi Wang

“…The nutrient composition analysis showed that the fructose and glucose contents were not significantly different, and sucrose and vitamin C contents were significantly higher in SD fruits compared with CV and RS fruits. …”
Get full text

Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound by Ruchi Roy, Janet Zayas, Sunil K Singh, Kaylee Delgado, Stephen J Wood, Mohamed F Mohamed, Dulce M Frausto, Yasmeen A Albalawi, Thea P Price, Ricardo Estupinian, Eileena F Giurini, Timothy M Kuzel, Andrew Zloza, Jochen Reiser, Sasha H Shafikhani

“…Here, we report that exposure to glucose in diabetic range results in impaired chemotaxis signaling through the formyl peptide receptor (FPR) in neutrophils, culminating in reduced chemotaxis and delayed neutrophil trafficking in the wound of Leprdb (db/db) type two diabetic mice, rendering diabetic wound vulnerable to infection. …”
Get full text

Altering palmitic acid and stearic acid ratios in the diet of early-lactation Holsteins under heat stress: Feed intake, digestibility, feeding behavior, milk yield and composition,... by O. Ramezani Afarani, A. Zali, M. Dehghan-Banadaki, A. Kahyani, M. Asemi Esfahani, F. Ahmadi

“…A linear reduction in blood nonesterified fatty acids and glucose was detected as the ratio of PA to SA decreased. …”
Get full text

Sex-specific differences in atherosclerosis, thrombospondin-1, and smooth muscle cell differentiation in metabolic syndrome versus non-metabolic syndrome mice by Shreya Gupta, Shreya Gupta, Saugat Khanal, Saugat Khanal, Neha Bhavnani, Neha Bhavnani, Amy Mathias, Jason Lallo, Ariana Kiriakou, Jessica Ferrell, Jessica Ferrell, Priya Raman, Priya Raman

“…The goal of this study was to examine sex-specific differences in lesion progression in a model of combined MetS and atherosclerosis (KKAyApoE) and interrogate how these differences relate to TSP-1 expression.MethodsMale and female KKAy+/−ApoE–/– (with ectopic agouti gene expression) and age-matched non-agouti KKAy–/–ApoE–/– littermates were placed on a standard laboratory diet from 4 to 24 weeks age followed by blood and tissue harvests for biochemical, molecular, and aortic root morphometric studies.ResultsMetabolic profiling confirmed MetS phenotype of KKAy+/−ApoE–/–; however, only male genotypes were glucose intolerant with elevated VLDL-cholesterol and VLDL-triglyceride levels. …”
Get full text

Sleep quality in women with diabetes in pregnancy: a single-center retrospective study by Qizhen Wu, Zhaoyan Meng, Qing Liu, Lili Zhang, Baohong Mao, Cheng Wang, Min Zhou, Zhi Zhang, Dehua Yang, Ruirui Jin, Tongying Yi

“…Sleep disorders associated with diabetes in pregnancy can greatly endanger the health of both mothers and babies, and their hazards are strongly associated with blood glucose levels. This study explored the quality of sleep and sleep disorders in pregnant women with diabetes. …”
Get full text

Cardiac and Metabolic Impact of Functional Foods with Antioxidant Properties Based on Whey Derived Proteins Enriched with Hemp Seed Oil by Teresa Pasqua, Carmine Rocca, Francesca Romana Lupi, Noemi Baldino, Daniela Amelio, Ortensia Ilaria Parisi, Maria Concetta Granieri, Anna De Bartolo, Arturo Lauria, Marco Dattilo, Ida Daniela Perrotta, Francesco Puoci, Maria Carmela Cerra, Domenico Gabriele, Tommaso Angelone

“…All the supplementations did not induce significant changes in biochemical and metabolic variables, also in relation to glucose tolerance, and livers did not undergo morphological alteration and injury. …”
Get full text

Microbial Phenolic Metabolites in Urine Are Inversely Linked to Certain Features of Metabolic Syndrome in Spanish Adolescents by Emily P. Laveriano-Santos, Paola Quifer-Rada, María Marhuenda-Muñoz, Camila Arancibia-Riveros, Anna Vallverdú-Queralt, Anna Tresserra-Rimbau, Ana María Ruiz-León, Rosa Casas, Ramon Estruch, Patricia Bodega, Mercedes de Miguel, Amaya de Cos-Gandoy, Jesús Martínez-Gómez, Gloria Santos-Beneit, Juan M. Fernández-Alvira, Rodrigo Fernández-Jiménez, Rosa M. Lamuela-Raventós

“…Higher urolithin B levels were inversely associated with abdominal obesity (OR = 0.94, 95% CI: 0.89; 0.98) and high blood glucose (OR = 0.92, 95% CI:0.88; 0.96); (4) Conclusions: gallic acid, urolithin A and B were associated with lower odds of presenting MetS or some of its clinical features in adolescents. …”
Get full text

Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental va... by Fang Cheng, Jie Zhang, Pan Yang, Zufei Chen, Yinghao Fu, Jiajia Mi, Xingliang Xie, Sha Liu, Yanmei Sheng

“…The principal active ingredients and their optimal proportions in this combination have been identified through the oxygen and glucose deprivation (OGD) cell model, including astragaloside A, chlorogenic acid and scutellarin (ACS), and its efficacy in enhancing the survival of OGD PC12 cells surpasses that of the combination preparation. …”
Get full text

Yeast polysaccharide supplementation: impact on lactation, growth, immunity, and gut microbiota in Dezhou donkeys by Bingjian Huang, Bingjian Huang, Muhammad Zahoor Khan, Muhammad Zahoor Khan, Yinghui Chen, Yinghui Chen, Huili Liang, Xiyan Kou, Xinrui Wang, Wei Ren, Changfa Wang, Zhenwei Zhang

“…Additionally, YPS was associated with increased plasma glucose and creatinine concentrations in foals, while tending to decrease alkaline phosphatase, white blood cell count, red blood cell count, and hemoglobin levels (p < 0.10). …”
Get full text

Association between hemoglobin glycation index and 5-year major adverse cardiovascular events: the REACTION cohort study by Yuhan Wang, Hongzhou Liu, Xiaodong Hu, Anping Wang, Anning Wang, Shaoyang Kang, Lingjing Zhang, Weijun Gu, Jingtao Dou, Yiming Mu, Kang Chen, Weiqing Wang, Zhaohui Lyu, Xiuyuan Hao

“…The hemoglobin glycation index (HGI) was developed to quantify glucose metabolism and individual differences and proved to be a robust measure of individual glycosylated hemoglobin (HbA1c) bias. …”
Get full text

Effects of mid-to-late prepartum feed supplementation in Hanwoo beef cows on their performance, blood metabolites, and the carcass characteristics and metabolites of their neonatal... by Myung Sun Park, Borhan Shokrollahi, Borhan Shokrollahi, Ui Hyung Kim, Jeong Il Won, Soo-Hyun Cho, Shil Jin, Sung Sik Kang, Sung Jin Moon, Kyung-Hwan Um, Ki Suk Jang, Hyoun Ju Kim, Nam Young Kim, Sung Woo Kim, Sun Sik Jang, Hyun-Jeong Lee

“…Blood metabolite analysis for the cows revealed decreased levels of triglycerides (TGLate), non-esterified fatty acids (NEFALate), and progesterone (P4Late), with a notable increase in glucose (GluLate) levels (p <0.01). In the neonatal calves, anatomical metrics of the gastrointestinal tissues showed increased Omasum Width (OmasWdth) values in the supplemented group (p =0.053). …”
Get full text

Validation of the traditional Chinese version of the diabetes eating problem survey-revised and study of the prevalence of disordered eating patterns in Chinese patients with type... by Chi Wing Lok, Mei Cheung Wong, Kim Wai Yip, Wing Ka Ching, Edward Kwok Yiu Choi

“…There was a significant correlation of the C-DEPS-R with BMI, occurrence of DKA, use of a continuous glucose monitoring system and positive diagnosis by the CB-SCID-I/P module H (p < 0.05). …”
Get full text

Combining thermosonication microstress and pineapple peel extract addition to achieve quality and post-acidification control in yogurt fermentation by Xiaohui Zhang, Yuanrong Zheng, Changyu Zhou, Jinxuan Cao, Yifeng Zhang, Zhen Wu, Daodong Pan, Zhendong Cai, Qiang Xia

“…The results of targeted metabolomics indicated the proposed combination strategy significantly modified the microbial metabolism, leading to the delayed utilization of lactose and the inhibited conversion into glucose during post-fermentation, as well as the decreased lactic acid production and a notable shift towards the formation of relatively weak acids such as succinic acid and citric acid. …”
Get full text

Tyrosine phosphorylation of band 3 impairs the storage quality of suspended red blood cells in the Tibetan high-altitude polycythemia population by Xiaodong Wu, Zhijuan Liu, Doudou Hao, Qin Zhao, Wanjing Li, Maodi Xie, Xia Feng, Xia Liao, Siyuan Chen, Siyu Wang, Chaohua Zhou, Wenchun Long, Yajun Zhong, Shen Li, Ye Cao, Hong Wang, Aiping Wang, Yuehong Xu, Min Huang, Jiaxin Liu, Rui Zhong, Yunhong Wu, Zeng He

“…Overall, we found that tyrosine 21 phosphorylation activated glycolysis by releasing glycolytic enzymes from the cytosolic domain of band 3, thus increasing glucose consumption and lactate accumulation during storage, in the HAPC group. …”
Get full text